Patents by Inventor Alban Gaultier

Alban Gaultier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR REGULATING INFLAMMATION
    Publication number: 20220023291
    Abstract: Provided are methods for treating inflammation in subject in need thereof. In some embodiments, the methods include administering to the subject an effective amount of a Sigma-1 receptor (S1R) activity modulator to thereby treat inflammation in the subject. Also provided are pharmaceutical compositions that include an effective amount of a Sigma-1 receptor (S1R) activity modulator and uses of the pharmaceutical compositions to treat inflammation in a subject in need thereof.
    Type: Application
    Filed: December 5, 2019
    Publication date: January 27, 2022
    Applicant: University of Virginia Patent Foundation
    Inventors: Dorian A. Rosen, Alban Gaultier
  • METHODS OF PROMOTING CNS NEURONAL REPAIR BY INHIBITING LRP-1
    Publication number: 20210284708
    Abstract: This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
    Type: Application
    Filed: November 5, 2020
    Publication date: September 16, 2021
    Applicant: The J. David Gladstone Institutes
    Inventors: Steven L. Gonias, Travis Stiles, Alban Gaultier, Wendy M. Campana, Katerina Akassoglou
  • COMPOSITIONS AND METHODS FOR REGULATING MYELINATION
    Publication number: 20210269808
    Abstract: Relapsing remitting multiple sclerosis (RRMS) is the most common form of multiple sclerosis, affecting more than 80% of MS patients. RRMS is comprised of two phases: the auto-inflammatory episodes, in which the immune system is actively destroying myelin, alternate with remission phases. Currently there is no cure for this devastating disease. The present disclosure provides compositions and methods useful for inducing remyelination. The methods are useful for promoting remyelination to treat diseases and disorders such as MS. The present disclosure describes compositions and methods useful for inhibiting LRP1 activity. In one aspect, a siRNA against LRP1 can be used. It is disclosed that myelination can be regulated by inhibiting the interaction of LRP1 and p75NTR and that it inhibits activation of Rho-A.
    Type: Application
    Filed: March 21, 2017
    Publication date: September 2, 2021
    Applicant: University of Virginia Patent Foundation
    Inventors: Alban Gaultier, Anthony Fernandez-Castaneda
  • Methods of promoting CNS neuronal repair by inhibiting LRP-1
    Patent number: 10829536
    Abstract: This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: November 10, 2020
    Assignee: The Regents of the University of California
    Inventors: Steven L. Gonias, Travis Stiles, Alban Gaultier, Wendy M. Campana, Katerina Akassoglou
  • METHODS OF PROMOTING CNS NEURONAL REPAIR BY INHIBITING LRP-1
    Publication number: 20190284254
    Abstract: This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
    Type: Application
    Filed: June 22, 2016
    Publication date: September 19, 2019
    Applicant: The J. David Gladstone Institutes
    Inventors: Steven L. Gonias, Travis Stiles, Alban Gaultier, Wendy M. Campana, Katerina Akassoglou
  • Methods of promoting CNS neuronal repair by inhibiting LRP-1
    Patent number: 9376481
    Abstract: This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
    Type: Grant
    Filed: April 26, 2012
    Date of Patent: June 28, 2016
    Assignees: The Regents of the University of California, J. David Gladsone Institutes
    Inventors: Steven L. Gonias, Travis Stiles, Alban Gaultier, Wendy M. Campana, Katerina Akassoglou
  • METHODS OF PROMOTING CNS NEURONAL REPAIR BY INHIBITING LRP-1
    Publication number: 20140161807
    Abstract: This invention provides methods for promoting and/or restoring neurite outgrowth and neuronal regeneration by contacting an injured neuron with an inhibitor of low density lipoprotein receptor-related protein-1 (LRP-1).
    Type: Application
    Filed: April 26, 2012
    Publication date: June 12, 2014
    Applicant: The Regents of The University of California
    Inventors: Steven L. Gonias, Travis Stiles, Alban Gaultier, Wendy M. Campana, Katerina Akassoglou