Patents by Inventor Albert G. Caldwell

Albert G. Caldwell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of 3-(arylmethyleneamino)-1-aryl-2-pyrazolines in the prophylaxis and treatment of inflammation, pain, pyresis, and asthma
    Patent number: 4572913
    Abstract: Compounds of formula (I) ##STR1## inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid oxygenation and are useful in medicine as, e.g., anti-inflammatory and anti-asthmatic agents.The compounds may be administered as the raw chemical or in association with a carrier as a pharmaceutical formulation.The compounds may be prepared by methods analogous to those known in the art, e.g., by the method of Duffin and Kendall in J. Chem. Soc. (1954), 408-415, or by other methods.
    Type: Grant
    Filed: December 15, 1981
    Date of Patent: February 25, 1986
    Assignee: Burroughs Wellcome Co.
    Inventors: Frederick C. Copp, Albert G. Caldwell, David Collard
  • 3-Amino-1-phenyl-2-pyrazolines
    Patent number: 4564684
    Abstract: Heterocyclic compounds of formula (I) and acid addition salts thereof inhibit arachidonic acid oxygenation and are useful in medicine, for example as anti-inflammatory agents. ##STR1## The compounds of formula (I) may be prepared by any method analogous to those known in the art, for example by the method of G. F. Duffin and J. D. Kendall in J. Chem. Soc. (1954), 408-415. When used in medicine, the compounds of formula (I) may be administered as the compound alone or as a pharmaceutical formulation together with a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: May 23, 1984
    Date of Patent: January 14, 1986
    Inventors: Frederick C. Copp, Albert G. Caldwell, David Collard
  • Hydantoin derivatives and pharmaceutical use
    Patent number: 4486443
    Abstract: Hydantoins of formula (I) ##STR1## have biological properties related to those of naturally occurring prostaglandins and may be used in medicine, for example in the treatment of thrombosis.
    Type: Grant
    Filed: March 10, 1980
    Date of Patent: December 4, 1984
    Assignee: Burroughs Wellcome Co.
    Inventors: Albert G. Caldwell, Norman Whittaker
  • Antiinflammatory pyrazole thioureas
    Patent number: 4465685
    Abstract: Compounds of formula (I) ##STR1## inhibit both the cyclo-oxygenase and lipoxygenase pathways of arachidonic acid oxygenation and are useful in medicine as, e.g., anti-inflammatory and anti-asthmatic agents.The compounds may be administered as the raw chemical or in association with a carrier as a pharmaceutical formulation.The compounds may be prepared by methods analogous to those known in the art, e.g. by the method of Duffin and Kendall in J. Chem. Soc. (1954), 408-415, or by other methods.
    Type: Grant
    Filed: December 15, 1981
    Date of Patent: August 14, 1984
    Assignee: Burroughs Wellcome Co.
    Inventors: Frederick C. Copp, Albert G. Caldwell, David Collard
  • Hydantoin derivatives, pharmaceutical compounds and methods of use
    Patent number: 4337262
    Abstract: Hydantoins of formula (I) ##STR1## have biological properties related to those of naturally occurring prostaglandins and may be used in medicine, for example in the treatment of thrombosis.
    Type: Grant
    Filed: November 30, 1978
    Date of Patent: June 29, 1982
    Assignee: Burroughs Wellcome Co.
    Inventors: Norman Whittaker, Albert G. Caldwell
  • Nitrogen heterocycles
    Patent number: 4289707
    Abstract: 1,3,6-Trisubstituted piperazine-2,5-diones having biological properties related to those of the natural prostaglandins, their synthesis, compositions containing them, and their use in medicine.
    Type: Grant
    Filed: March 21, 1978
    Date of Patent: September 15, 1981
    Assignee: Burroughs Wellcome Co.
    Inventors: Albert G. Caldwell, Norman Whittaker
  • Nitrogen heterocycles
    Patent number: 4262128
    Abstract: Hydantoins of formula (I) ##STR1## ps have biological properties related to those of naturally occurring prostaglandins and may be used in medicine, for example in the treatment of thrombosis.
    Type: Grant
    Filed: May 31, 1978
    Date of Patent: April 14, 1981
    Assignee: Burroughs Wellcome Co.
    Inventors: Albert G. Caldwell, Norman Whittaker
  • Nitrogen heterocycles
    Patent number: 4204068
    Abstract: Hydantoins and N-alkylhydantoins of formula (I) ##STR1## have biological properties related to those of naturally occurring prostaglandins and maybe used in medicine, for example in the treatment of thrombosis.
    Type: Grant
    Filed: June 2, 1977
    Date of Patent: May 20, 1980
    Assignee: Burroughs Wellcome Co.
    Inventors: Albert G. Caldwell, Norman Whittaker