Patents by Inventor Albert Po-Fu Chen

Albert Po-Fu Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190025387
    Abstract: A cooling system is provided. The cooling system is associated with a dynamic nuclear polarization system and configured to cool a sample to a temperature suitable for dynamic nuclear polarization to be carried out on the sample while the sample is in the cooling system. The cooling system includes a cryogenic chamber that includes a cryogenic fluid. The cooling system also includes a removable sample sleeve insertable within a portion of the cryogenic chamber. The removable sample sleeve is configured to define a sample path for the sample within the cryogenic chamber that is isolated from other parts of the cooling system.
    Type: Application
    Filed: July 24, 2017
    Publication date: January 24, 2019
    Inventors: Ernst Wolfang Stautner, Jan Henrik Ardenkjaer-Larsen, Patrick L. Padgett, Jonathan Alan Murray, Rui Chen, James Richard Trigger, Arnaud Comment, Albert Po-Fu Chen
  • Patent number: 9283317
    Abstract: Disclosed embodiments for assessing brown adipose tissue use imaging of metabolic contrast agents. For example, activated brown adipose tissue may be assessed by evaluating a difference in production of the hyperpolarized 13C metabolic contrast agent from a pre-polarized 13C metabolic contrast agent precursor before and after exposure of the subject to an activating event or agent. In one embodiment, the subject is given a dose of norepinephrine, and the production of the hyperpolarized 13C metabolic contrast agent before and after the dose is assessed.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 15, 2016
    Assignee: General Electric Company
    Inventors: Angus Zoen Lau, Albert Po-Fu Chen, Charles H. Cunningham
  • Patent number: 8933697
    Abstract: The use of selective RF excitation is discussed. A spectrally selective, large tip angle RF pulse is used to detect a weak signal from a first chemical species. A non-selective, small tip angle pulse is used in measuring a signal from a second chemical species in exchange with the first chemical species. The acquired resonance data provides maybe used to measure the ratio of the spectrally distinct species in exchange.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: January 13, 2015
    Assignee: General Electric Company
    Inventors: Albert Po-Fu Chen, Ralph Eugene Hurd
  • Publication number: 20140275969
    Abstract: Disclosed embodiments for assessing brown adipose tissue use imaging of metabolic contrast agents. For example, activated brown adipose tissue may be assessed by evaluating a difference in production of the hyperpolarized 13C metabolic contrast agent from a pre-polarized 13C metabolic contrast agent precursor before and after exposure of the subject to an activating event or agent. In one embodiment, the subject is given a dose of norepinephrine, and the production of the hyperpolarized 13C metabolic contrast agent before and after the dose is assessed.
    Type: Application
    Filed: March 15, 2013
    Publication date: September 18, 2014
    Applicant: General Electric Company
    Inventors: Angus Zoen Lau, Albert Po-Fu Chen, Charles H. Cunningham
  • Publication number: 20130154637
    Abstract: The use of selective RF excitation is discussed. A spectrally selective, large tip angle RF pulse is used to detect a weak signal from a first chemical species. A non-selective, small tip angle pulse is used in measuring a signal from a second chemical species in exchange with the first chemical species. The acquired resonance data provides maybe used to measure the ratio of the spectrally distinct species in exchange.
    Type: Application
    Filed: December 19, 2011
    Publication date: June 20, 2013
    Applicant: General Electric Company
    Inventors: Albert Po-Fu Chen, Ralph Eugene Hurd