Patents by Inventor Alessandro Fraldi

Alessandro Fraldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITION OF LIPOFUSCIN AGGREGATION BY MOLECULAR TWEEZERS
    Publication number: 20210069217
    Abstract: In various embodiments methods for the treatment and/or prophylaxis of lipofuscin-related disorders are provided. In certain embodiments the methods involve administration of an effective amount of a molecular tweezers to a subject in need thereof.
    Type: Application
    Filed: April 25, 2019
    Publication date: March 11, 2021
    Inventors: Gal Bitan, Alessandro Fraldi, Alberto Auricchio, Antonio Monaco
  • TREATMENT OF LYSOSOMAL STORAGE DISORDERS
    Publication number: 20210052611
    Abstract: In various embodiments methods are provided for the treatment or prophylaxis of liposomal storage diseases. In certain embodiments the methods involve administering to a subject in need thereof one or more molecular tweezers that inhibit protein aggregation.
    Type: Application
    Filed: April 25, 2019
    Publication date: February 25, 2021
    Applicants: The Regents of the University of California, Fondazione Telethon, Fondazione Telethon
    Inventors: Gal Bitan, Alessandro Fraldi, Irene Sambri, Antonio Monaco
  • Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
    Patent number: 9487766
    Abstract: The invention provides for nucleotide sequences encoding for a chimeric sulfatase, viral vectors expressing such sequences for gene therapy and pharmaceutical uses of the chimeric expressed protein. The invention is particularly applied in the therapy of mucopolysaccharidosis, preferably type IIIA.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 8, 2016
    Assignee: FOND AZIONE TELETHON
    Inventors: Andrea Ballabio, Alessandro Fraldi
  • THERAPEUTIC STRATEGIES TO TREAT CNS PATHOLOGY IN MUCOPOLYSACCHARIDOSES
    Publication number: 20160122731
    Abstract: The invention provides for nucleotide sequences encoding for a chimeric sulfatase, viral vectors expressing such sequences for gene therapy and pharmaceutical uses of the chimeric expressed protein. The invention is particularly applied in the therapy of mucopolysaccharidosis, preferably type IIIA.
    Type: Application
    Filed: November 12, 2015
    Publication date: May 5, 2016
    Inventors: Andrea BALLABIO, Alessandro FRALDI
  • Therapeutic strategies to treat CNS pathology in mucopolysaccharidoses
    Patent number: 9206401
    Abstract: The invention provides for nucleotide sequences encoding for a chimeric sulfatase, viral vectors expressing such sequences for gene therapy and pharmaceutical uses of the chimeric expressed protein. The invention is particularly applied in the therapy of mucopolysaccharidosis, preferably type IIIA.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: December 8, 2015
    Assignee: FONDAZIONE TELETHON
    Inventors: Andrea Ballabio, Alessandro Fraldi
  • THERAPEUTIC STRATEGIES TO TREAT CNS PATHOLOGY IN MUCOPOLYSACCHARIDOSES
    Publication number: 20130302308
    Abstract: The invention refers to nucleotide sequence encoding for a chimeric sulfatase, viral vectors expressing such sequences for gene therapy and pharmaceutical uses of the chimeric expressed protein. The invention is particularly applied in the therapy of mucopolysaccharidosis, preferably type IIIA.
    Type: Application
    Filed: December 22, 2010
    Publication date: November 14, 2013
    Applicant: FONDAZIONE TELETHON
    Inventors: Andrea Ballabio, Alessandro Fraldi