Patents by Inventor Alessandro Nencioni

Alessandro Nencioni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10646586
    Abstract: The present invention concerns the preparation and the therapeutic use of aqueous solutions of Progesterone or Testosterone, complexed with hydroxypropyl-3-cyclodextrin (HP?CD) that are suitable for oral administration. The solutions are characterised by a specific molar ratio between HP?CD and the hormones such as to ensure high hormone plasma levels, following oral administration, thanks to the optimisation of their solubility, permeability, metabolic stability and ultimately, bio availability. The formulation object of the present patent makes it possible to achieve effective plasma concentrations following oral administration of lower doses of hormone with respect to oral formulations currently on the market (e.g. Prometrium, Andriol) to the advantage of greater safety and compliance of the patients.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: May 12, 2020
    Assignee: ALTERGON S.A.
    Inventors: Alberto Bernareggi, Nadia Puppini, Alessandro Nencioni
  • Publication number: 20150297752
    Abstract: The present invention concerns the preparation and the therapeutic use of aqueous solutions of Progesterone or Testosterone, complexed with hydroxypropyl-3-cyclodextrin (HP?CD) that are suitable for oral administration. The solutions are characterised by a specific molar ratio between HP?CD and the hormones such as to ensure high hormone plasma levels, following oral administration, thanks to the optimisation of their solubility, permeability, metabolic stability and ultimately, bio availability. The formulation object of the present patent makes it possible to achieve effective plasma concentrations following oral administration of lower doses of hormone with respect to oral formulations currently on the market (e.g. Prometrium, Andriol) to the advantage of greater safety and compliance of the patients.
    Type: Application
    Filed: November 22, 2013
    Publication date: October 22, 2015
    Inventors: Alberto BERNAREGGI, Nadia PUPPINI, Alessandro NENCIONI
  • Patent number: 7790490
    Abstract: The invention concerns a manufacturing process, and the related micromachined capacitive ultra-acoustic transducer, that uses commercial silicon wafer 8 already covered on at least one or, more preferably, on both faces by an upper layer 9 and by a lower layer 9? of silicon nitride deposited with low pressure chemical vapour deposition technique, or deposition LPCVD deposition. One of the two layers 9 or 9? of silicon nitride, of optimal quality, covering the wafer 8 is used as emitting membrane of the transducer. As a consequence, the micro-cell array 6 forming the CMUT transducer is grown onto one of the two layers of silicon nitride, i.e. it is grown at the back of the transducer with a sequence of steps that is reversed with respect to the classical technology.
    Type: Grant
    Filed: March 2, 2006
    Date of Patent: September 7, 2010
    Assignees: Consiglio Nazionale Delle Ricerche, Esaote S.p.A.
    Inventors: Giosuè Caliano, Alessandro Caronti, Vittorio Foglietti, Elena Cianci, Antonio Minotti, Alessandro Nencioni, Massimo Pappalardo
  • Publication number: 20080212407
    Abstract: The invention concerns a manufacturing process, and the related micromachined capacitive ultra-acoustic transducer, that uses commercial silicon wafer 8 already covered on at least one or, more preferably, on both faces by an upper layer 9 and by a lower layer 9? of silicon nitride deposited with low pressure chemical vapour deposition technique, or deposition LPCVD deposition. One of the two layers 9 or 9? of silicon nitride, of optimal quality, covering the wafer 8 is used as emitting membrane of the transducer. As a consequence, the micro-cell array 6 forming the CMUT transducer is grown onto one of the two layers of silicon nitride, i.e. it is grown at the back of the transducer with a sequence of steps that is reversed with respect to the classical technology.
    Type: Application
    Filed: March 2, 2006
    Publication date: September 4, 2008
    Applicants: CONSIGLIO NAZIONALE DELLE RICERCHE, ESAOTE S.P.A.
    Inventors: Giosue Caliano, Alessandro Caronti, Vittorio Foglietti, Elena Cianci, Antonio Minotti, Alessandro Nencioni, Massimo Pappalardo