Abstract: A descaling arrangement for a dishwasher and an associated apparatus are provided. The dishwasher has a tub portion adapted to receive dishware therein, and a fluid circulation system configured to circulate dishwashing fluid about the dishware within the tub portion. A descale system is in fluid communication with the fluid circulation system. The descale system is configured to selectively introduce a descaling substance into dishwashing fluid circulated within the fluid circulation system such that the descaling substance is distributed to at least one of the tub portion and the fluid circulation system for descaling thereof. An associated method is also provided.

Abstract: The invention relates to compounds of formula (I) wherein R represents aryl or heteroaryl, X is a bond, a carbonyl group, a derivative of a carbonyl group, an ethylene group or an ethylenecarbonyl group, R1 is optionally substituted amino or hydroxy, and the substituents R2 to R6 have the meanings given in the specification, to methods of synthesis of such compounds, to pharmaceutical compositions containing compounds of formula (I), to intermediates, to the use of a compounds of formula (I) as a medicament and for the preparation of a pharmaceutical composition for the treatment of neoplastic and autoimmune diseases, and to methods of treatment of neoplastic and autoimmune diseases using such compounds of formula (I) or of pharmaceutical compositions containing same.

Abstract: An amplifier circuit for amplifying a differential input signal includes a first feedback resistance, a second feedback resistance, first transconductance circuitry, and second transconductance circuitry. The first feedback resistance is connected between a first input node and a first output node of the amplifier circuit. The second feedback resistance is connected between a second input node and a second output node of the amplifier circuit. The first transconductance circuitry is arranged to inject a transconductance current at a point along the first feedback resistance, and is configurable to vary the point along the first feedback resistance where the transconductance current is injected. The second transconductance circuitry is arranged to inject another transconductance current at a point along the second feedback resistance, and is configurable to vary the point along the second feedback resistance where the another transconductance current is injected.

Abstract: Rubber-reinforced vinyl aromatic polymers having a strictly bimodal morphology, comprising from 55 to 90% by weight of a rigid polymeric matrix and from 10 to 45% by weight of a rubbery phase dispersed inside said rigid polymeric matrix, in the form of grafted and occluded particles and wherein said rubber particles consist of from 60 to 99% by weight of particles with a capsule or “core-shell” morphology and from 1 to 40% by weight of particles with a “salami” morphology, said percentages being measured on the basis of the weight of the rubber particles only.

Abstract: A method is provided for determining an index representing the crank angle at which a given fuel mass fraction has been burnt in a cylinder of the engine during an engine cycle. The method includes, but is not limited to sampling the pressure within the cylinder during the engine cycle, using the pressure samples for determining the heat release rate curve during the engine cycle, using the heat release rate curve for determining the cumulative heat release curve during the engine cycle, determining a minimum value and a maximum value of thee cumulative heat release curve, using the given fuel mass fraction for calculating a target value of the cumulative heat release between the minimum and maximum values, finding a goal point of the cumulative heat release curve that corresponds to the target value, assuming the crank angle corresponding to the goal point as the index.

Abstract: A method is provided for estimating a pressure in an exhaust manifold of an internal combustion engine, the internal combustion engine having a combustion chamber with an associated exhaust valve, the method includes, but is not limited to acquiring pressure values within the combustion chamber during an acquisition period (AP) chosen within the time interval when the exhaust valve is open, and averaging the pressure values to obtain a single pressure value which is representative for the pressure in the exhaust manifold.

Abstract: The invention relates to a process for enzymatically catalyzed esterification of prostaglandins or analogues thereof.

Abstract: The authors describe an expression system for the correct, stable and effective expression in mammalian cells of a siRNA comprising: a) a polymerase II RNA-dependent promoter derived from the U1 RNA gene; downstream from the sequence b) suitable restriction sites for the cloning of the sequence transcribing the pre-siRNA; downstream from these sites c) sequences derived from the sequences at 3? of the gene for U1 snRNA that are necessary and sufficient for the correct formation of 3? of the presiRNA.

Abstract: A tile cutting machine includes a tub for receiving water and a tile to be cut therein. A cutting head assembly having a motor driven blade is positioned above a tile supporting surface located in the tub and is movable with respect thereto. A laser projects a line of light from the cutting head assembly down onto the tile supporting surface to provide a visual representation of a cutting path of the blade. A scale permits measurement of a tile to be cut. The laser may be used with the scale to allow a user to quickly determine cutting widths without the need to manually mark the object to be cut. A light source, such as an LED, may be incorporated in the cutting head to illuminate an interior of the tub during operation of the tile cutting machine.

Abstract: The voltage regulator receives power in A.C. from a permanent magnet voltage generator, having phase windings with a configurable connection, to supply power in D.C. to a battery. The voltage regulator comprises a plurality of semi-bridge rectifiers connected between the terminals of the phase windings of the voltage generator, and a battery power supply terminal; it also comprises a control circuit designed to change over the connection of the phase windings between two different configurations, for example star and delta, in relation to the charging voltage of the battery upon exceeding a threshold value of the phase frequency of the voltage generator.

Abstract: Flow in a data network is policed by determining a measure of greediness of a flow through a node, comparing the measure of greediness with a measure indicative of acceptable greediness dependent on the expected greediness of a compliant flow experiencing substantially similar path conditions, and designating the flow for possible sanction in the event that the greediness is not in accordance with the acceptable greediness. Such allows for the policing of a data network when one or more fields in a data packet that carry information relating to a characterization of an end-to-end path and/or a downstream path of the data packet are used in order to police the data network.

Abstract: A caliper for a fixed twin rotor disc brake includes a relatively fixed body, two yokes movable axially with respect to the body, formations defined on the yokes for receiving four brake pads for respective application to rotor sides, and an actuator adapted to urge the yokes relatively axially. One of the yokes is operable to urge two of the four brake pads in a first axial direction, the other of the yokes is operable to urge the other two of the four brake pads in a second, opposite axial direction. The four brake pads are positioned on a first side of the actuator in the first axial direction.

Abstract: A method is disclosed for locating a terminal in a local wireless telecommunications network adapted to provide an estimated position of the terminal depending on a set of configuration data and a set of measuring data indicating whether the terminal belongs to a subset of said coverage areas and acquired from the terminal or network. The set of configuration data has a plurality of data bases of configurations, each one having a respective weight function, and the set of measuring data has a plurality of measuring types, depending on the type of terminal. A method for associating, to every combination of a data base of configurations and a measuring type, a respective locating procedure corresponding to an accuracy value of the locating estimation and actuating the locating procedure related to a combination selected by executing a related processing program. A processing system and a processing program or group of programs can be executed by the system and arranged to perform the above method.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: In one or more of the disclosed embodiments, a punch-through disturb effect in a memory device can be reduced by biasing a selected word line at a program voltage to program a selected memory cell, biasing word lines on the drain side of the series string with a Vpass voltage, turning off an adjacent memory cell to the selected memory cell, and biasing remaining word lines on the source side of the turned-off memory cell with a Vlow voltage that is less than Vpass.

Abstract: The invention relates to aryl-sulphonamido compounds endowed with affinity against metallo proteases MMP, having formula (I) below wherein R, R1, R2, R3, G and n have the meanings reported in the specification, properly labelled with diagnostic imaging moieties or even radiotherapeutic moieties. The invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as diagnostic imaging agents or radiotherapeutic agents.

Abstract: The present invention relates to a process for the preparation of Brinzolamide, or 2H-thieno[3,2-e]-1, 2-thiazin-6-sulfonamide, 4-(ethyl amino)-3, 4-dihydro-2-(3-methoxypropyl)-, 1,1-dioxide,(4R)- via intermediates 2,3-dihydro-4H-thieno[3,2-e]-1, 2-thiazin-4-ones, 1,1-dioxide. Further objects of the present invention are the intermediates mentioned above and other intermediates of the synthesis.

Abstract: Selected fused imidazole or triazole derivatives are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: In a method and a device for determining the fluorescence of a sample, wherein the sample (40) is irradiated by light (25) of a wavelength which is suitable to excite fluorescent light (27, 28) in the sample and the fluorescent light (28) emitted by the sample is received in a receiver (24) and converted into a measurement signal, wherein reference light (32) in particular for compensating for ambient influences is additionally fed to the receiver (24) and likewise converted into a reference measurement signal, provision is made for the optical path of the excitation light (25) entering the sample (40) and fluorescent light (27, 28) leaving the sample (40) to be separated from the optical path (32) of the reference light having the same wavelength as the excitation light between light sources (21, 31) and receiver (24), by means of which a more precise evaluation of the fluorescent light emitted by a sample (40) can be achieved in addition to a simplified design complexity.

Abstract: Assemblies or MEA devices (Membrane Electrode Assembly) comprising a membrane and two electrocatalytic layers on each side thereof, wherein: the area of each of the two electrocatalytic layers is lower than that of the membrane; on each of the two sides of the ionomeric membrane there is at least one subgasket, applied on the MEA non catalyzed area; the edges of the ionomeric membranes being enclosed among said subgaskets.