Patents by Inventor Alexander Alisch

Alexander Alisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STIRRER SYSTEM
    Publication number: 20180187138
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: November 1, 2017
    Publication date: July 5, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius
  • STIRRER SYSTEM
    Publication number: 20150175952
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: November 26, 2014
    Publication date: June 25, 2015
    Applicant: HOFFMANN-LA ROCHE INC.
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius
  • STIRRER SYSTEM
    Publication number: 20120135464
    Abstract: The present invention concerns a stirrer system for animal cell culture consisting of a combination of at least one radially-conveying stirrer element and at least one axially-conveying stirrer element, wherein at least three stirrer elements must be present and the uppermost stirrer element is an axially-conveying stirrer element. The stirrer elements are arranged at a certain distance above one another on a stirrer shaft. A particular embodiment is a multiple stirrer system consisting of two disk stirrers as radially-conveying stirrer elements and an inclined-blade stirrer as an axially-conveying stirrer element wherein the inclined-blade stirrer is arranged above the disk stirrer on the stirrer shaft. The stirrer system according to the invention achieves among others a gentler and better intermixing in the culture of shear-sensitive mammalian cells in cell cultures.
    Type: Application
    Filed: July 23, 2010
    Publication date: May 31, 2012
    Inventors: Alexander Alisch, Marco Jenzsch, Michael Pohlscheidt, Joerg Thiele, Claus Wallerius