Patents by Inventor Alexander Langereis
Alexander Langereis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240058436Abstract: The present invention regards recombinant HVT (rHVT) constructs, useful as multivalent vector vaccine for poultry. The rHVT comprise 4 heterologous genes from poultry pathogens: the VP2 gene from IBDV, the F gene from NDV, and the gD and gI genes from ILTV. The VP2 and F genes are inserted in the Us genome region of the rHVT. The gD-gI genes are inserted in the UL genome region, either between UL44 and UL45, or between UL45 and UL46. The rHVTs proved to be genetically stable in vitro and in vivo, and expressed all inserted genes well enough to induce protective immunity in vaccinated poultry against IBDV, NDV, and ILTV.Type: ApplicationFiled: December 23, 2021Publication date: February 22, 2024Applicant: Intervet Inc.Inventors: Martijn Alexander Langereis, Iwan Verstegen
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Publication number: 20240024456Abstract: The present invention relates to vaccines against influenza virus infection or disease for targets with pre-existing antibodies against influenza virus HA head domain. The invention regards a recombinant vector expressing a HA stem polypeptide, a vaccine comprising the vector or a host cell with said vector, uses of the vector, the host cell, or the vaccine, and methods for reducing influenza virus infection or disease. The recombinant vector can be a nucleic acid such as a eukaryotic expression plasmid or an RNA, a virus, or a replicon particle (RP). This vaccination allows for the induction of an early- and effective immune-response against Influenza virus induced infection or disease, not hindered by pre-existing anti-HA head domain antibodies.Type: ApplicationFiled: September 6, 2021Publication date: January 25, 2024Applicant: Intervet Inc.Inventors: Martijn Alexander Langereis, Iwan Verstegen, Maria Alexander Cornelis De Haan
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Publication number: 20240000920Abstract: The present invention provides recombinant vectors encoding a chimeric coronavirus spike protein. The present invention further provides new immunogenic compositions and vaccines comprising these recombinant vectors. Methods of administering these immunogenic compositions and vaccines to animal subjects, including humans, felines, and avians, to protect them against coronaviruses also are included. Methods of making the immunogenic compositions and vaccines alone or in combinations with other protective agents are provided too.Type: ApplicationFiled: November 11, 2021Publication date: January 4, 2024Applicant: Intervet Inc.Inventors: Martijn Alexander Langereis, Ad De Groof, Paul Vermeij, Berend Jan Bosch
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Publication number: 20230031097Abstract: The present invention describes a recombinant herpesvirus of turkeys (rHVT) that can be used as a vector vaccine for poultry against infection and disease from multiple poultry pathogens. Specifically the rHVT expresses an infectious bursal disease virus (IBDV) viral protein 2 (VP2) gene and a Newcastle disease virus (NDV) fusion (F) protein gene from a first and a second expression cassette inserted in the unique small (Us) region, and expresses an avian influenza vims (AIV) haemagglutinin (HA) gene from a third expression cassette inserted in the unique long (UL) region of the genome of said rHVT either between the UL40 and UL41 genes, or between the UL44 and UL45 genes. This rHVT can be used to vaccinate poultry against MDV, IBDV, NDV and AIV.Type: ApplicationFiled: December 18, 2020Publication date: February 2, 2023Applicant: Intervet Inc.Inventors: Martijn Alexander Langereis, Iwan Verstegen
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Patent number: 11412523Abstract: Methods, apparatus and computer programs for controlling the output of a transmission point. A method for controlling the output of a transmission point for a wireless communications network. The method comprises: determining an average output power of the transmission point over a period of time; comparing the average output power to an output power reference value; and allocating data, to be transmitted by the transmission point to one or more wireless devices, to a pool of radio resources. The pool of radio resources is adjusted as a function of the comparison between the average output power and the output power reference value.Type: GrantFiled: December 20, 2018Date of Patent: August 9, 2022Assignee: Telefonaktiebolaget LM Ericsson (publ)Inventors: Torbjörn Wigren, Billy Hogan, Alexander Langereis, Yali Pei, Yuan Wang, Christer Törnevik
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Publication number: 20210337559Abstract: Methods, apparatus and computer programs for controlling the output of a transmission point. A method for controlling the output of a transmission point for a wireless communications network. The method comprises: determining an average output power of the transmission point over a period of time; comparing the average output power to an output power reference value; and allocating data, to be transmitted by the transmission point to one or more wireless devices, to a pool of radio resources. The pool of radio resources is adjusted as a function of the comparison between the average output power and the output power reference value.Type: ApplicationFiled: December 20, 2018Publication date: October 28, 2021Inventors: Torbjörn WIGREN, Billy HOGAN, Alexander LANGEREIS, Yali PEI, Yuan WANG, Christer TÖRNEVIK
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Patent number: 10925012Abstract: Embodiments include methods of operating a user equipment (UE) in a serving cell provided by a base station in a cellular communications network. These embodiments include establishing a Radio Resource Control (RRC) connection with the base station, such that the UE is operating in an RRC Connected state according to a first value of a parameter (e.g., a time alignment timer value) affecting the UE's uplink synchronization with the serving cell. These embodiments also include initiating a reconfiguration of the RRC connection towards the base station and, in response to initiating the reconfiguration, receiving from the base station a second value of the parameter affecting the UE's uplink synchronization with the serving cell. These embodiments also include operating in an RRC Connected state according to the second value of the parameter. Other embodiments include UEs configured to perform operations corresponding to these methods.Type: GrantFiled: July 31, 2019Date of Patent: February 16, 2021Assignee: Telefonaktiebolaget LM Ericsson (publ)Inventor: Alexander Langereis
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Patent number: 10841883Abstract: Embodiments herein relate to a method, performed by a network node, for handling of specific power reduction for a User Equipment (UE). The network node receives a message from the UE comprising an identification of a specific type of the UE. The network node obtains a reduced power applied by the UE corresponding to the received identification. The network node selects an allocation for transmissions from the UE, based on the reduced power applied by the UE. Embodiments herein further relate to a network node for performing the method for handling of specific power reduction for a UE.Type: GrantFiled: May 10, 2016Date of Patent: November 17, 2020Assignee: Telefonaktiebolaget LM Ericsson (publ) StockholmInventors: Alexander Langereis, Magnus Finne, Mikael Jonsson, Magnus Hurd, Liping Wang, Jing Rao, Stéphane Tessier, Jianwei Zhang
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Publication number: 20190357163Abstract: Embodiments include methods of operating a user equipment (UE) in a serving cell provided by a base station in a cellular communications network. These embodiments include establishing a Radio Resource Control (RRC) connection with the base station, such that the UE is operating in an RRC Connected state according to a first value of a parameter (e.g., a time alignment timer value) affecting the UE's uplink synchronization with the serving cell. These embodiments also include initiating a reconfiguration of the RRC connection towards the base station and, in response to initiating the reconfiguration, receiving from the base station a second value of the parameter affecting the UE's uplink synchronization with the serving cell. These embodiments also include operating in an RRC Connected state according to the second value of the parameter. Other embodiments include UEs configured to perform operations corresponding to these methods.Type: ApplicationFiled: July 31, 2019Publication date: November 21, 2019Inventor: Alexander Langereis
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Patent number: 10420046Abstract: A method of operating a base station in a cellular communications network, in which Radio Resource Control (RRC) connected user equipment devices can be kept synchronized with the cell on the uplink or become unsynchronized. The method comprises determining whether a specified condition within a cell served by the base station is fulfilled, and, in response to determining whether the specified condition is fulfilled, determining whether RRC connected user equipment devices should be kept uplink synchronized with the cell, or whether RRC connected user equipment devices should be allowed to become uplink unsynchronized. Signals are transmitted to RRC connected user equipment devices to affect whether or not such devices are kept uplink synchronized with the cell, in response to determining whether RRC connected user equipment devices should be kept uplink synchronized with the cell, or whether RRC connected user equipment devices should be allowed to become unsynchronized on the uplink.Type: GrantFiled: February 26, 2018Date of Patent: September 17, 2019Assignee: Telefonaktiebolaget LM Ericsson (publ)Inventor: Alexander Langereis
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Patent number: 10412597Abstract: Systems and methods for selectively enabling Robust Header Compression (RoHC) for Voice over Internet Protocol (VoIP) calls in a cellular communications network are disclosed. In one embodiment, a data radio bearer for a VoIP call is established between a base station and a mobile terminal. During the VoIP call, a radio frequency parameter for the data radio bearer is monitored. When the radio frequency parameter for the data radio bearer satisfies a predefined coverage-based condition, the base station enables RoHC for the VoIP call. In one preferred embodiment, the radio frequency parameter is a Signal-to-Interference-plus-Noise Ratio (SINR) for the data radio bearer for the VoIP call, and the predefined coverage-based condition is a predefined SINR threshold below which the base station enables RoHC. By enabling RoHC in this manner, RoHC resources are selectively made available for those VoIP calls that will benefit most from increased cell coverage provided by RoHC.Type: GrantFiled: August 7, 2018Date of Patent: September 10, 2019Assignee: Telefonaktiebolaget L M Ericsson (publ)Inventors: Jayson Chan, Alexander Langereis, Eva Englund
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Patent number: 10349439Abstract: It is presented a method for releasing semi-persistent scheduling, SPS, for a wireless device. The method is performed in a network node and comprising the steps of: transmitting an SPS release message to the wireless device to release uplink SPS; starting a timer; when a first condition is true, transmitting a grant for uplink transmission to the wireless device, the first condition being true when the timer expires and/or a scheduling request has been received from the wireless device; receiving a data type indication from the wireless device; and determining that an SPS release message has been correctly received by the wireless device when a scheduling request has been received from the wireless device, the grant has been transmitted and the data type indication indicates only voice over internet protocol, VoIP, data from the wireless device.Type: GrantFiled: January 23, 2014Date of Patent: July 9, 2019Assignee: Telefonaktiebolaget LM Ericsson (publ)Inventors: Alexander Langereis, Saad Naveed Ahmed, Don Corry, David Sandberg
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Patent number: 10342015Abstract: A network node identifies a fixed periodic pattern to be used for scheduling a half-duplex (HD) user equipment (UE), the fixed periodic pattern defining a sequence of at least one downlink (DL) subframe, then at least one guard period, and then at least one uplink (UL) subframe. The network node then performs DL assignments for the network node according to the fixed periodic pattern and transmits UL grants to the UE according to the fixed periodic pattern.Type: GrantFiled: August 19, 2016Date of Patent: July 2, 2019Assignee: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)Inventors: Alexander Langereis, Prabaharan Kanesalingam, Björn Nordström
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Publication number: 20190150101Abstract: Embodiments herein relate to a method, performed by a network node, for handling of specific power reduction for a User Equipment (UE). The network node receives a message from the UE comprising an identification of a specific type of the UE. The network node obtains a reduced power applied by the UE corresponding to the received identification. The network node selects an allocation for transmissions from the UE, based on the reduced power applied by the UE. Embodiments herein further relate to a network node for performing the method for handling of specific power reduction for a UE.Type: ApplicationFiled: May 10, 2016Publication date: May 16, 2019Inventors: Alexander Langereis, Magnus Finne, Mikael Jonsson, Magnus Hurd, Liping Wang, Jing Rao, Stéphane Tessier, Jianwei Zhang
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Patent number: 10159109Abstract: A node and method for extending a wake up time of a wireless user equipment (UE) are provided. The node includes a memory. The memory is configured to store data to be transmitted to the UE. The node includes a processor configured to determine if the memory is storing data to be transmitted to the UE, determine if the wake up time of the UE coincides with a periodic subframe, the periodic subframe occurring with a periodicity and cause transmission of a message for a grant to the UE if the determination is made that the memory is storing data to be transmitted to the UE and the wake up time of the UE coincides with the periodic subframe.Type: GrantFiled: July 18, 2014Date of Patent: December 18, 2018Assignee: TELEFONAKTIEBOLAGET LM ERICSSON (PUBL)Inventors: Prabaharan Kanesalingam, Chandra Sekhar Bontu, Alexander Langereis, Patrick Lie Chin Cheong
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Publication number: 20180343569Abstract: Systems and methods for selectively enabling Robust Header Compression (RoHC) for Voice over Internet Protocol (VoIP) calls in a cellular communications network are disclosed. In one embodiment, a data radio bearer for a VoIP call is established between a base station and a mobile terminal. During the VoIP call, a radio frequency parameter for the data radio bearer is monitored. When the radio frequency parameter for the data radio bearer satisfies a predefined coverage-based condition, the base station enables RoHC for the VoIP call. In one preferred embodiment, the radio frequency parameter is a Signal-to-Interference-plus-Noise Ratio (SINR) for the data radio bearer for the VoIP call, and the predefined coverage-based condition is a predefined SINR threshold below which the base station enables RoHC. By enabling RoHC in this manner, RoHC resources are selectively made available for those VoIP calls that will benefit most from increased cell coverage provided by RoHC.Type: ApplicationFiled: August 7, 2018Publication date: November 29, 2018Inventors: Jayson Chan, Alexander Langereis, Eva Englund
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Patent number: 10085156Abstract: Systems and methods for selectively enabling Robust Header Compression (RoHC) for Voice over Internet Protocol (VoIP) calls in a cellular communications network are disclosed. In one embodiment, a data radio bearer for a VoIP call is established between a base station and a mobile terminal. During the VoIP call, a radio frequency parameter for the data radio bearer is monitored. When the radio frequency parameter for the data radio bearer satisfies a predefined coverage-based condition, the base station enables RoHC for the VoIP call. In one preferred embodiment, the radio frequency parameter is a Signal-to-Interference-plus-Noise Ratio (SINR) for the data radio bearer for the VoIP call, and the predefined coverage-based condition is a predefined SINR threshold below which the base station enables RoHC. By enabling RoHC in this manner, RoHC resources are selectively made available for those VoIP calls that will benefit most from increased cell coverage provided by RoHC.Type: GrantFiled: October 11, 2016Date of Patent: September 25, 2018Assignee: Telefonaktiebolaget L M Ericsson (publ)Inventors: Jayson Chan, Alexander Langereis, Eva Englund
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Publication number: 20180255549Abstract: A network node identifies a fixed periodic pattern to be used for scheduling a half-duplex (HD) user equipment (UE), the fixed periodic pattern defining a sequence of at least one downlink (DL) subframe, then at least one guard period, and then at least one uplink (UL) subframe. The network node then performs DL assignments for the network node according to the fixed periodic pattern and transmits UL grants to the UE according to the fixed periodic pattern.Type: ApplicationFiled: August 19, 2016Publication date: September 6, 2018Inventors: Alexander LANGEREIS, Prabaharan KANESALINGAM, Björn NORDSTRÖM
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Publication number: 20180192388Abstract: A method of operating a base station in a cellular communications network, in which Radio Resource Control (RRC) connected user equipment devices can be kept synchronized with the cell on the uplink or become unsynchronized. The method comprises determining whether a specified condition within a cell served by the base station is fulfilled, and, in response to determining whether the specified condition is fulfilled, determining whether RRC connected user equipment devices should be kept uplink synchronized with the cell, or whether RRC connected user equipment devices should be allowed to become uplink unsynchronized. Signals are transmitted to RRC connected user equipment devices to affect whether or not such devices are kept uplink synchronized with the cell, in response to determining whether RRC connected user equipment devices should be kept uplink synchronized with the cell, or whether RRC connected user equipment devices should be allowed to become unsynchronized on the uplink.Type: ApplicationFiled: February 26, 2018Publication date: July 5, 2018Inventor: Alexander Langereis
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Patent number: 9949222Abstract: A method of operation of a base station in a cellular communications network, in which user equipment devices in a cell served by the base station need to be synchronized with the cell on the uplink in order to transmit data, and in which Radio Resource Control, RRC, connected user equipment devices can be kept synchronized with the cell on the uplink or not synchronized. The method comprises making a determination as to whether a specified condition within the cell served by the base station is fulfilled, and, in response to the determination as to whether the specified condition within the cell is fulfilled, determining whether RRC connected user equipment devices should be kept uplink synchronized with the cell, or whether RRC connected user equipment devices should be allowed to become not synchronized on the uplink.Type: GrantFiled: September 2, 2014Date of Patent: April 17, 2018Assignee: Telefonaktiebolaget LM Ericsson (publ)Inventor: Alexander Langereis