Patents by Inventor Alexander M. Schobel
Alexander M. Schobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150190476Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.Type: ApplicationFiled: February 9, 2015Publication date: July 9, 2015Inventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
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Publication number: 20150157717Abstract: A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and release the taste masked active agent. The disintegrable film includes at least one water soluble polymer and a taste masked ketoprofen active. Also provided are methods for preparing the solid dosage form and for using the solid dosage to administer an effective dosage of an active agent, such as ketoprofen, into the oral cavity for absorption.Type: ApplicationFiled: February 17, 2015Publication date: June 11, 2015Inventors: Alexander M. Schobel, Shyam S. Vangala
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Patent number: 8986735Abstract: A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and release the taste masked active agent. The disintegrable film includes at least one water soluble polymer and a taste masked ketoprofen active. Also provided are methods for preparing the solid dosage form and for using the solid dosage to administer an effective dosage of an active agent, such as ketoprofen, into the oral cavity for absorption.Type: GrantFiled: March 15, 2007Date of Patent: March 24, 2015Assignee: Novartis AGInventors: Alexander M Schobel, Shyam S Vangala
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Patent number: 8974826Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.Type: GrantFiled: June 10, 2011Date of Patent: March 10, 2015Assignees: Monosol RX, LLC, Midatech LimitedInventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
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Publication number: 20120009260Abstract: A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform a therapeutic or bioeffecting function.Type: ApplicationFiled: June 10, 2011Publication date: January 12, 2012Inventors: Alexander M. Schobel, Garry L. Myers, Keith Joseph Kendall, Thomas Rademacher, Jan Mous, Justin N. W. Barry, Phillip Williams, Africa Garcia Barrientos
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Patent number: 5681577Abstract: A chewable cold/sinus preparation comprising a bitter tasting mixture of a decongestant such as pseudoephedrine and an antihistamine such as diphenhydramine and/or chlorpheniramine maleate is made with no bitter, metallic taste or unpleasant mouthfeel by adsorbing the active drug mixture using a wet granulation process onto a silicon dioxide carrier which comprises from about 50 to about 85% of total weight of the adsorbate composition. A truly multi-symptom relief formula is prepared through the optional addition of an antitussive such as dextromethorphan hydrobromide and/or an analgesic such as meclofenamic acid, aspirin or ibuprofen. Additional excipients such as flavors, sweeteners, lubricants and bulk fillers are added for better taste, improved mouthfeel and as an aid to the tabletting process.Type: GrantFiled: September 19, 1995Date of Patent: October 28, 1997Assignee: Warner-Lambert CompanyInventors: Stanley Lech, Alexander M. Schobel, John Denick, Jr.
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Patent number: 5093387Abstract: A denture adhesive base composition comprises a substantially anhydrous mixture of a cationic derivatives of guar gum, a mixed Na/Ca salt of methyl vinyl ether-maleic anhydride and sodium carboxymethylcellulose. A denture adhesive composition including this base composition is provided, as well as a method for formulating the novel adhesives of the invention. Upon hydration, the denture adhesives of the invention form denture adhesive compositions exhibiting improved denture holding and adhesive duration properties.Type: GrantFiled: December 21, 1989Date of Patent: March 3, 1992Assignee: Warner-Lambert CompanyInventors: Alexander M. Schobel, Lori D. Kumar
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Patent number: 5006571Abstract: A denture adhesive base composition comprising a substantially anhydrous mixture of a mixed Na/Ca salt of methyl vinyl ether-maleic acid, sodium carboxymethylcellulose, and a trivalent cation. A denture adhesive composition including this base composition is provided, as well as a method for formulating the novel adhesives of the invention.Type: GrantFiled: December 21, 1989Date of Patent: April 9, 1991Assignee: Warner-Lambert CompanyInventors: Lori D. Kumar, Alexander M. Schobel
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Patent number: 4980391Abstract: The present invention pertains to denture adhesive compositions comprising a substantially anhydrous mixture, in percentages by weight, of an adhesive component comprised of a mixture of (a) from about 29 to about 34% of a mixed, partial calcium/sodium salt of a methyl vinyl ether-maleic anhydride-type copolymer, and (b) from about 22 to about 26% sodium carboxymethylcellulose; a vehicle component comprises of a mixture of (c) from about 20 to about 26% petrolatum and from about 15 to about 24% mineral oil; and a hydration and tackifier component comprised of (d) from about 0.5 to about 2% silicon dioxide and (e) from about 1 to about 3% poly(ethylene oxide) homopolymer. The present invention also pertains to methods by which these denture adhesive compositions may be prepared.Type: GrantFiled: October 27, 1988Date of Patent: December 25, 1990Assignee: Warner-Lambert CompanyInventors: Lori D. Kumar, Alexander M. Schobel
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Patent number: 4911934Abstract: The present invention comprises a chewing gum composition having extended sweetness release including a chewing gum base, an extended release encapsulated sweetening agent in a coating material including a hydrophobic polymer and a hydrophobic plasticizer. The chewing gum composition has sweeteness release of up to 30 minutes during mastication.Type: GrantFiled: December 19, 1986Date of Patent: March 27, 1990Assignee: Warner-Lambert CompanyInventors: Robert K. Yang, Alexander M. Schobel
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Patent number: 4824681Abstract: The present invention comprises the encapsulation of a sweetening agent in a coating material including a hydrophobic polymer and a hydrophobic plasticizer. The encapsulated sweetening agent is protected from deterioration due to moisture and provides controlled release of sweetener in products intended to be chewed during consumption.Type: GrantFiled: December 19, 1986Date of Patent: April 25, 1989Assignee: Warner-Lambert CompanyInventors: Alexander M. Schobel, Robert K. Yang
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Patent number: 4719181Abstract: A test reagent system and method for detecting the presence of peroxidase-like activity is provided by the present invention. The reagent system comprises a free-flowing granular indicator material comprising a granular substrate such as sorbitol or mannitol having coated thereon gum guaiac and an aqueous organic reagent solution containing water, an organic solvent, an oxidizing agent being capable of oxidizing the indicator material in the presence of peroxidase-like activity, and a buffer.Type: GrantFiled: December 20, 1985Date of Patent: January 12, 1988Assignee: Warner-Lambert CompanyInventors: Alexander M. Schobel, Raymond L. Mohrle
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Patent number: 4687662Abstract: Effervescent compositions in the form of tablets or powders comprising a therapeutic agent, a granulating agent, a microparticulate effervescent component and an effervescent system which dissolve rapidly in water to yield an effervescent solution containing a completely dissolved therapeutic agent and a process for their preparation.Type: GrantFiled: January 15, 1986Date of Patent: August 18, 1987Assignee: Warner-Lambert CompanyInventor: Alexander M. Schobel
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Patent number: 4671972Abstract: A denture cleansing composition of the hypochlorite type is rendered substantially free of hypochlorite chlorine odor by incorporating into the composition a hypochlorite deactivator. The deactivator is released into the cleansing solution at a controlled rate to optimize cleansing efficacy at a reduced hypochlorite/chlorine odor. The deactivators suitable for use in this invention include sodium perborate monohydrate and sodium nitrite. The preferred method of controlling deactivator release rate is by encapsulating the deactivator.Type: GrantFiled: October 9, 1985Date of Patent: June 9, 1987Assignee: Warner-Lambert CompanyInventors: Alexander M. Schobel, Robert W. Schumacher
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Patent number: 4568560Abstract: Process for preparing a controlled release encapsulated active agent by encapsulating the active agent in a coating composition comprising a water insoluble film forming composition, an enteric compound and a plasticizer for the film forming composition.Type: GrantFiled: March 16, 1984Date of Patent: February 4, 1986Assignee: Warner-Lambert CompanyInventor: Alexander M. Schobel
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Patent number: 4552679Abstract: A denture cleansing composition of the hypochlorite type is rendered substantially free of hypochlorite chlorine odor by incorporating into the composition a hypochlorite deactivator. The deactivator is released into the cleansing solution at a controlled rate to optimize cleansing efficacy at a reduced hypochlorite/chlorine odor. The deactivators suitable for use in this invention include sodium perborate monohydrate and sodium nitrite. The preferred method of controlling deactivator release rate is by encapsulating the deactivator.Type: GrantFiled: March 16, 1984Date of Patent: November 12, 1985Assignee: Warner-Lambert CompanyInventors: Alexander M. Schobel, Robert W. Schumacher