Abstract: A nucleic acid amplifier may include a sample preparation zone, a fluid ejector, an amplification zone and a capillary break between the amplification zone and the fluid ejector.

Abstract: An immiscible droplet generation system may include a chip, a microfluidic channel integrated into the chip, an input to the microfluidic channel through which the microfluidic channel is to be filled with a first fluid that is to be moved through the microfluidic channel and a droplet generator. The droplet generator is integrated into the chip to generate a droplet of a second fluid, immiscible within the first fluid, and to inject the droplet into the first fluid in the microfluidic channel.

Abstract: In some examples, a fluid dispensing device includes a fluid chamber, a heating element adjacent the fluid chamber, and an orifice adjacent the fluid chamber. A ratio of an area of a surface of the heating element to an orifice area of the orifice is greater than or equal to 3, where the surface of the heating element faces the fluid chamber.

Abstract: A microfluidic magnetic microbead interaction method may include mixing ferromagnetic microbeads in a fluid while the fluid is at a first temperature above a Curie temperature of the ferromagnetic microbeads, applying a magnetic field to the ferromagnetic microbeads while the fluid is at a second temperature at or below the Curie temperature of the ferromagnetic microbeads and withdrawing remaining supernatant portions of the fluid while the magnetic field is applied to the ferromagnetic microbeads.

Abstract: A microfluidic device may include at least four interconnected microfluidic channels and a set of fluid actuators. The set of fluid actuators may include a fluid actuator asymmetrically located within at least two of the at least four interconnected microfluidic channels. Each of the at least four interconnected microfluidic channels may be activated to a fluid inputting state, a fluid outputting state and a fluid blocking state in response to selective actuation of different combinations of fluid actuators of the set.

Abstract: An example method for measuring deformability of a cell via a pressure field, consistent with the present disclosure, includes flowing a biologic sample containing a plurality of cells along a first fluidic channel and into an intersection between the first fluidic channel and a second fluidic channel of a microfluidic device. The method includes introducing a pressure field at the intersection and into the first fluidic channel via the second fluidic channel and a plurality of apertures in a channel wall disposed in the intersection. The method further includes measuring deformability of a cell among the plurality of cells responsive to the introduction of the pressure field.

Abstract: An example method for measuring deformability of a cell responsive to a pressure wave, consistent with the present disclosure, includes moving a cell of a sample into a cell probing chamber of a microfluidic device. While the cell is in the cell probing chamber, the method includes generating a pressure wave within the cell probing chamber by actuating a fluidic pump. The method further includes determining a deformability of the cell responsive to the pressure wave, using an imaging array synchronized with the actuation of the fluidic pump.

Abstract: A microfluidic sensing assembly may include a first structure supporting a sensor array, a second structure joined to the first structure and forming a microfluidic passage and a flat lens to focus light, following reflection of the light back and forth across the microfluidic passage, from the microfluidic passage onto the sensor array.

Abstract: A microfluidic valve may include a first portion of a liquid conduit to contain a gas, a second portion of a liquid conduit to contain a liquid, and a constriction between the first portion and the second portion and across which a capillary meniscus is to form between the gas and the liquid. The microfluidic valve may further include a drop jetting device within the second portion to open the valve by breaking the capillary meniscus across the constriction.

Abstract: A microfluidic flow sensor may include a substrate having a microfluidic channel, an inert particle source to supply a fluid carrying an inert particle to the microfluidic channel and a sensor element along the microfluidic channel and spaced from the inert particle source. The sensor element outputs a signal based upon a sensed passage of the inert particle with respect to the sensor element. Portions of the microfluidic channel proximate the sensor element have a first size and wherein the inert particle provided by the inert particle source is to have a second size greater than one half the first size.

Abstract: An integrated fluid ejection and imaging system may include a fluid ejector to eject a droplet of fluid onto a deposition site on a target, an imager to image the deposition site and a packaging supporting the fluid ejector and imager such that the fluid ejector and the imager are concurrently aimed at the deposition site on the target.

Abstract: An integrated fluid ejection and spectroscopic sensing system may include a fluid ejector to eject a droplet of fluid through an ejection orifice towards a deposition site, a sensor array, a dispersive element to project light onto the sensor array. The dispersive element, the sensor and the fluid ejector are joined as part of an integrated unit.

Abstract: An example device with a microfluidic channel for use in a chamber is provided, the example device comprising: a chamber to contain a fluid; a microfluidic channel located internal to the chamber, the microfluidic channel having an entrance within the chamber and an exit within the chamber, the microfluidic channel defined by a housing located within the chamber; a unidirectional displacement mechanism inside the microfluidic channel, the unidirectional displacement mechanism located between the entrance and the exit; and a controller to activate the unidirectional displacement mechanism to cause the fluid from the chamber to enter the microfluidic channel via the entrance and leave the microfluidic channel via the exit thereby agitating the fluid within the chamber, the fluid otherwise being non-moving.

Abstract: A microfluidic valve may include a firing chamber having an orifice, a first portion of a liquid conduit connected to the firing chamber at a first port, a second portion of the liquid conduit connected to the firing chamber at a second port and a thermal resistor. The thermal resistor is to form a bubble within the firing chamber to expel liquid from the firing chamber through the orifice such that a first meniscus forms across the first port and a second meniscus forms across the second port to interrupt liquid flow between the first portion and the second portion of the liquid conduit.

Abstract: A microfluidic device may include a valve located between a liquid source and a liquid receiver. The valve may include a channel connecting the liquid source to the liquid receiver, a heater within the channel, and a pinch point in the channel between the heater and the liquid receiver. The microfluidic device may include a controller to activate the heater so as to form a bubble sized so as to be captured by the pinch point in the channel to occlude the channel.

Abstract: A microfluidic device may include a first fluid chamber, a second fluid chamber, a first microfluidic passage extending between the first fluid chamber and the second fluid chamber, a second microfluidic passage extending from the second fluid chamber, a first fluid actuator adjacent the first microfluidic passage and proximate the first fluid chamber to inertially pump fluid away from the first fluid chamber and a second fluid actuator adjacent the first microfluidic passage and proximate the second fluid chamber to menially pump fluid towards the first fluid chamber.

Abstract: An object focuser may include a substrate, a sample fluid passage supported by the substrate, a first inertial pump supported by the substrate to pump a sample fluid entraining an object through the sample fluid passage, a first sheath fluid passage, a second inertial pump supported by the substrate to pump a first sheath fluid through the first sheath fluid passage, a second sheath fluid passage and a second inertial pump supported by the substrate to pump a second sheath fluid through the second sheath fluid passage. The first sheath fluid passage and the second sheath fluid passage are connected to the sample fluid passage at a convergence on opposite sides of the sample fluid passage.

Abstract: A sample-reagent mixture is thermal cycled through a plurality of cycles. Each thermal cycle includes actuating a heater to heat the sample-reagent mixtures; and dispensing a fluid onto the sample-reagent mixture to cool the sample reagent mixture.

Abstract: A microfluidic valve may include a first portion of a liquid conduit to contain a fluid, a second portion of the liquid conduit to contain a liquid and a constriction between the first portion and the second portion and across which a capillary meniscus is to form between the fluid and liquid, the constriction comprising an edge along a ceiling of the constriction.

Abstract: A microfluidic immunoassay platform may include a substrate, a microfluidic channel in the substrate, a first set of functionalized structures along the channel, a second set of functionalized structures along the channel and an electrically driven fluid actuator contained on the substrate to move fluid containing at least one analyte along the channel through the first set of functionalized structures and through the second set of functionalized structures.