Abstract: A method for detecting in-vivo properties of a biosensor. In the inventive method, a sensitivity-to-admittance relation is provided and a raw current in the biosensor is measured. An in-vivo current response is also measured at first and second operating points. A time constant ? is determined by the electrical capacitance C of the working electrode and the electrical resistance RM of the membrane by ?=RM·C. The first and second operating points are selected below and above ?, respectively. An analyte value in a sample of a body fluid is determined by using the raw current and compensating sensitivity drift in the biosensor, which in turn is compensated by using the measured value for the raw current and a corrected value for the sensitivity. The failsafe operation of the biosensor is monitored by using the in-vivo current response measured at the first and second operating points.

Abstract: A medical sensor system comprising a sensor implantable under the skin of a user and an on-body module attachable to the skin in the region of the implantable sensor, wherein the on-body module has a self-adhering flexible electronics patch including a first transmitter which is operable to exchange data with the implantable sensor via a short-range wireless connection.

Abstract: A sensor system (110), a method of manufacturing a flexible electronics patch (114) for use in a sensor system (110) and a method of manufacturing a sensor system (110). The sensor system (110) comprises—at least one analyte sensor (112) configured for at least partial implementation into a body tissue of a user; —at least one flexible electronics patch (114), the flexible electronics patch (114) comprising—at least one applicator unit (134) for applying the flexible electronics patch (114) to the skin (132) of the user; and —at least one second adhesive layer (136) for adhering the flexible electronics patch (114) to the applicator unit (134) before applying the flexible electronics patch (114) to the skin (132) of the user.

Abstract: A sensor system (110), a method of manufacturing a flexible electronics patch (114) for use in a sensor system (110) and a method of manufacturing a sensor system (110) are disclosed.

Abstract: A method for detecting in-vivo properties of a biosensor. In the inventive method, a sensitivity-to-admittance relation is provided and a raw current in the biosensor is measured. An in-vivo current response is also measured at first and second operating points. A time constant ? is determined by the electrical capacitance C of the working electrode and the electrical resistance RM of the membrane by ?=RM·C. The first and second operating points are selected below and above ?, respectively. An analyte value in a sample of a body fluid is determined by using the raw current and compensating sensitivity drift in the biosensor, which in turn is compensated by using the measured value for the raw current and a corrected value for the sensitivity. The failsafe operation of the biosensor is monitored by using the in-vivo current response measured at the first and second operating points.

Abstract: This disclosure concerns a medical sensor system comprising a sensor implantable under the skin of a user and an on-body module attachable to the skin in the region of the implantable sensor, wherein the on-body module has a self-adhering flexible electronics patch including a first transmitter which is operable to exchange data with the implantable sensor via a short-range wireless connection.

Abstract: The disclosure concerns a body-wearable medical device, such as an analyte monitoring system or a patch-mounted pump. The device has a self-adhering flexible electronics patch which adheres to the skin of a user and is deformable to follow the contour of the skin. In order to provide a flexible non-body configuration, the electronics patch includes flexible printed circuitry which is applied directly on a foil substrate. A user interface is configured for a user to control the device.