Patents by Inventor Alexandros Yiannikouris

Alexandros Yiannikouris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200123191
    Abstract: The present disclosure provides compounds of formulas (1)-(3), and compositions and methods of use thereof. The present disclosure also provides methods of preparing a provided compound and composition, and methods of characterizing a provided compound and composition.
    Type: Application
    Filed: May 1, 2018
    Publication date: April 23, 2020
    Applicant: Alltech, Inc.
    Inventors: Zi-Jian LAN, Ronan POWER, Alexandros YIANNIKOURIS, Thirupathi Reddy YERRAMREDDY
  • Patent number: 10472484
    Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: November 12, 2019
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Thirupathi R. Yerramreddy, Joshua J. Martinez, Jeffrey R. Withers
  • Patent number: 10201559
    Abstract: The present application relates to compositions comprising selenium compounds, such as 5?-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, Gamma-glutamyl-methylseleno-cysteine, a compound of formula (I), formula (II), a compound of formula (III) and combinations thereof, and methods of using the same in enhancing mitochondrial function, or treating mitochondrial dysfunction.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: February 12, 2019
    Assignee: Alltech, Inc.
    Inventors: Ronan Power, Zi-Jian Lan, Alexandros Yiannikouris
  • Publication number: 20180163011
    Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.
    Type: Application
    Filed: January 12, 2018
    Publication date: June 14, 2018
    Applicant: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Thirupathi R. Yerramreddy, Joshua J. Martinez, Jeffrey R. Withers
  • Patent number: 9902830
    Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: February 27, 2018
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Thirupathi R. Yerramreddy, Joshua J. Martinez, Jeffrey R. Withers
  • Publication number: 20160361338
    Abstract: The present application relates to compositions comprising selenium compounds, such as 5?-Methylselenoadenosine, Se-Adenosyl-L-homocysteine, Gamma-glutamyl-methylseleno-cysteine, a compound of formula (I), formula (II), a compound of formula (III) and combinations thereof, and methods of using the same in enhancing mitochondrial function, or treating mitochondrial dysfunction.
    Type: Application
    Filed: March 14, 2014
    Publication date: December 15, 2016
    Applicant: Alltech, Inc.
    Inventors: Ronan Power, Zi-Jian Lan, Alexandros Yiannikouris
  • Publication number: 20160347923
    Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 1, 2016
    Applicant: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Thirupathi R. Yerramreddy, Joshua J. Martinez, Jeffrey R. Withers
  • Publication number: 20160221983
    Abstract: Molecularly imprinted polymers (MIPs) are materials exhibiting molecular recognition of a target molecule. MIPs are synthesized in the presence of an aflatoxin template, a mimic to the targeted molecule, used as an imprint that is further washed away with suitable solvent after completion of the polymerization process, leaving a cavity in the polymer of the same stereochemistry, functionality and morphology to the template. When the MIP encounters an aflatoxin, the molecule is bound in the cavity with a receptor-like affinity.
    Type: Application
    Filed: February 4, 2015
    Publication date: August 4, 2016
    Inventors: Alexandros Yiannikouris, Thirupathi R. Yerramreddy, Joshua J. Martinez, Jeffrey R. Withers
  • Patent number: 8951533
    Abstract: The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
    Type: Grant
    Filed: November 26, 2012
    Date of Patent: February 10, 2015
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Ursula Anne Thielen
  • Patent number: 8426541
    Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: April 23, 2013
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Stefan Kwiatkowski, Manoj Bojappa Kudupoje, Clayton Matney
  • Publication number: 20130084356
    Abstract: The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
    Type: Application
    Filed: November 26, 2012
    Publication date: April 4, 2013
    Inventors: Alexandros Yiannikouris, Ursula Anne Thielen
  • Patent number: 8318475
    Abstract: The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: November 27, 2012
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Ursula Anne Thielen
  • Publication number: 20120214897
    Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
    Type: Application
    Filed: April 9, 2012
    Publication date: August 23, 2012
    Applicant: ALLTECH, INC.
    Inventors: Alexandros Yiannikouris, Stefan Kwiatkowski, Manoj Bojappa Kudupoje, Clayton Matney
  • Patent number: 8153737
    Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: April 10, 2012
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Stefan Kwiatkowski, Manoj Bojappa Kudupoje, Clayton Matney
  • Publication number: 20110281283
    Abstract: The present invention relates to animal feed additives and detection thereof in feed products. Additionally, the present invention relates to yeast cell wall components, their methods of isolation, and compositions and methods for the immunological detection thereof.
    Type: Application
    Filed: May 13, 2011
    Publication date: November 17, 2011
    Applicant: ALLTECH, INC.
    Inventors: Colm Moran, Stefan Kwiatkowski, Alexandros Yiannikouris, Ursula Anne Thielen
  • Publication number: 20110054132
    Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
    Type: Application
    Filed: August 27, 2010
    Publication date: March 3, 2011
    Applicant: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Stefan Kwiatkowski, Manoj Bojappa Kudupoje, Clayton Matney
  • Publication number: 20110033576
    Abstract: The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
    Type: Application
    Filed: August 13, 2010
    Publication date: February 10, 2011
    Applicant: ALLTECH, INC.
    Inventors: Alexandros Yiannikouris, Ursula Anne Thielen
  • Publication number: 20100178300
    Abstract: The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
    Type: Application
    Filed: January 14, 2010
    Publication date: July 15, 2010
    Applicant: ALLTECH, INC.
    Inventors: Alexandros Yiannikouris, Ursula Anne Thielen
  • Patent number: RE45274
    Abstract: The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
    Type: Grant
    Filed: April 8, 2014
    Date of Patent: December 2, 2014
    Assignee: Alltech, Inc.
    Inventors: Alexandros Yiannikouris, Stefan Kwiatkowski, Manoj Bojappa Kudupoje, Clayton Matney