Patents by Inventor Alexej I. Smirnov

Alexej I. Smirnov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11119165
    Abstract: Aspects of photonic band gap resonators for magnetic resonance are described. In one example, an apparatus includes a 1D structure having a plurality of layers. A respective thickness of the individual layers is one-quarter of a respective wavelength of a target magnetic resonance frequency within the individual layers of the plurality of layers, or a multiple thereof. A first layer has a first dielectric constant, and a second layer that is adjacent to the first layer has a second dielectric constant. A defect includes a sample. The defect has a thickness that is approximately up to one-half of a wavelength of the target magnetic resonance frequency within the defect.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: September 14, 2021
    Assignee: North Carolina State University Office of Research Commercialization
    Inventors: Alexander Nevzorov, Alexej I. Smirnov, Sergey Milikisiyants
  • Publication number: 20200158799
    Abstract: Aspects of photonic band gap resonators for magnetic resonance are described. In one example, an apparatus includes a 1D structure having a plurality of layers. A respective thickness of the individual layers is one-quarter of a respective wavelength of a target magnetic resonance frequency within the individual layers of the plurality of layers, or a multiple thereof. A first layer has a first dielectric constant, and a second layer that is adjacent to the first layer has a second dielectric constant. A defect includes a sample. The defect has a thickness that is approximately up to one-half of a wavelength of the target magnetic resonance frequency within the defect.
    Type: Application
    Filed: June 27, 2018
    Publication date: May 21, 2020
    Inventors: Alexander Nevzorov, Alexej I. Smirnov, Sergey Milikisiyants
  • Patent number: 10414729
    Abstract: Dynamic nuclear polarization (DNP) agents are provided for DNP nuclear magnetic resonance of analytes. The DNP agents can have the structure A-X-L-R, where A is none or an amphiphilic group; X is a coupling group capable of site-specific binding with the analyte or, when A is an amphiphilic group, capable of site-specific binding with the amphiphilic group; L is a bond or a linker group; and R is a poly-radical group. The poly-radical can be a di-radical, a tri-radical, a tetra-radical, or a combination thereof. Methods of NMR measurement of an analyte comprising an NMR-detectable nucleus are provided. The methods can include the steps of providing a frozen sample containing the analyte and a DNP agent; applying radiation having a frequency that excites electron spin transitions in the DNP agent at an intensity to polarize the NMR-detectable nucleus; and detecting a signal from nuclear spin transitions in the NMR-detectable nucleus.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: September 17, 2019
    Assignee: NORTH CAROLINA STATE UNIVERSITY
    Inventors: Alexej I. Smirnov, Maxim Anatolyevich Voynov
  • Publication number: 20170029377
    Abstract: Dynamic nuclear polarization (DNP) agents are provided for DNP nuclear magnetic resonance of analytes. The DNP agents can have the structure A-X-L-R, where A is none or an amphiphilic group; X is a coupling group capable of site-specific binding with the analyte or, when A is an amphiphilic group, capable of site-specific binding with the amphiphilic group; L is a bond or a linker group; and R is a poly-radical group. The poly-radical can be a di-radical, a tri-radical, a tetra-radical, or a combination thereof. Methods of NMR measurement of an analyte comprising an NMR-detectable nucleus are provided. The methods can include the steps of providing a frozen sample containing the analyte and a DNP agent; applying radiation having a frequency that excites electron spin transitions in the DNP agent at an intensity to polarize the NMR-detectable nucleus; and detecting a signal from nuclear spin transitions in the NMR-detectable nucleus.
    Type: Application
    Filed: July 28, 2016
    Publication date: February 2, 2017
    Inventors: Alexej I. Smirnov, Maxim Anatolyevich Voynov