Patents by Inventor Alfred Gagel
Alfred Gagel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11883572Abstract: The present invention relates to a dialysis machine that is configured to be equipped with an extracorporeal blood system comprising a dialysis solution system that is configured to be equipped with a dialyzer, wherein a mixing region, in particular a mixing chamber, is provided in which the fresh dialysis solution or a component thereof is located in the operation of the dialysis machine, with a concentrate line being in fluid communication with the mixing region, through which concentrate line concentrate can be conducted from a concentrate container into the mixing region, wherein at least two electrically conductive elements are arranged spaced apart from one another in or at the concentrate line or lines; that a measuring device is provided which is electrically connected to the conductive elements and which is configured to measure the conductance or a value correlated therewith between them; and that a control unit is provided which is configured to compare the measured value with a desired value, withType: GrantFiled: March 26, 2019Date of Patent: January 30, 2024Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Tobias Irrgang, Tilman Stäblein, Alfred Gagel, Peter Klöffel
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Publication number: 20230398273Abstract: The present disclosure relates to a medical treatment apparatus which includes at least one port, a device for closing, a compressed-air source and a control device and/or closed-loop control device. The port serves to establish fluid communication between at least one fluid line of the treatment apparatus associated with the interior of a treatment apparatus and a connector of a fluid line of a disposable associated with the exterior of the treatment apparatus. The sealing device is designed as a rinsing cap and serves to seal an interior of the port with respect to an exterior of the treatment apparatus. The compressed-air source is used to introduce air into the port along at least one sterile-air line. The control device and/or closed-loop control device is programmed to cause the compressed-air source to build-up and/or maintain a predetermined minimum overpressure in the sterile-air line, the compressed-air source and/or inside the port.Type: ApplicationFiled: October 6, 2021Publication date: December 14, 2023Inventors: Juergen Haecker, Burkard Keller, Peter Kloeffel, Martin Thys, Nico Roemmelt, Alfred Gagel, Soeren Gronau
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Publication number: 20230158217Abstract: The invention relates to an extracorporeal blood treatment apparatus comprising a blood treatment unit 1 that is divided by a semipermeable membrane 2 into a first compartment 3, which is part of a fluid system II, and a second compartment 4, which is part of an extracorporeal blood circuit I. The invention also relates to a method for operating a blood treatment apparatus of this kind. The blood treatment apparatus according to the invention has a pressure-based checking device 32 which interacts with the control unit 31 for a valve device 21 and is designed such that a fluid connection between an upstream portion 20A and a downstream portion 20B of a flow path 20 for a special operating mode can only be established if the pressure-based checking device 32 detects an operating state in which it is ensured that fluid in the flow path 20 for a special operating mode flows towards a flow path 10 leading to a drain 11.Type: ApplicationFiled: April 21, 2021Publication date: May 25, 2023Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alfred GAGEL, Burkard KELLER, Peter KLOEFFEL, Martin THYS
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Patent number: 11504459Abstract: A diagnosis method for a conductivity sensor for a dialysis fluid preparation apparatus and personal dialysis apparatus, that mix water, an A fluid and a B fluid in predetermined proportions respectively to prepare a dialysis fluid and measures the concentration of the prepared dialysis fluid by concentration measurement means is described. The diagnosis method and the respective apparatus is based in measuring the A fluid without the B fluid being present in the solution.Type: GrantFiled: January 3, 2018Date of Patent: November 22, 2022Assignee: FRESENTUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alfred Gagel, Tilman Staeblein
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Publication number: 20220280707Abstract: A method that regulates supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. An extracorporeal blood treatment apparatus that includes a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading. The selection of dialyzer parameters or blood parameters is therefore no longer necessary and the distinction between pre-dilution and post-dilution is also made obsolete.Type: ApplicationFiled: May 26, 2022Publication date: September 8, 2022Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Pascal KOPPERSCHMIDT, Alfred GAGEL
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Patent number: 11376353Abstract: The present invention relates to a method for regulating supply of substituate in an extracorporeal blood treatment with an extracorporeal blood treatment apparatus comprising a dialyzer divided by a semipermeable membrane into a blood chamber and a dialyzing fluid chamber and a device for supplying substituate. Moreover, the present invention relates to an extracorporeal blood treatment apparatus having a device for regulating supply of substituate. Regulation of supply of substituate in the extracorporeal blood treatment takes place as a function of the rheological loading of the dialyzer. To regulate supply of substituate during extracorporeal blood treatment, rheological loading of the dialyzer is determined from transmembrane pressure on the dialyzer and flow resistance of the dialyzer and substituate rate is increased or reduced according to the loading.Type: GrantFiled: November 16, 2010Date of Patent: July 5, 2022Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Pascal Kopperschmidt, Alfred Gagel
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Publication number: 20220096720Abstract: The present invention relates to an apparatus for an extracorporeal blood treatment having an extracorporeal blood circuit in which a dialyzer is arranged and having a dialyzate circuit, wherein the blood circuit is in fluid communication with a first chamber and the dialyzate circuit is in fluid communication with a second chamber of the dialyzer, and wherein the two chambers are separated from one another by a semipermeable membrane, with a dialyzate pump for a conveying of the dialysis solution being present in the dialyzate circuit, wherein the apparatus has a control unit that is configured to operate the apparatus in a first phase and in a second phase following the first phase, wherein the dialyzate pump is operated with a smaller flow rate in the first phase than in the second phase and/or wherein the dialyzate pump conveys a dialysis solution in the first phase that is of a higher concentration with respect to at least one component than in the second phase.Type: ApplicationFiled: January 24, 2020Publication date: March 31, 2022Applicant: Fresenius Medical Care Deutschland GmbHInventors: Reinder SPICKERMANN, Carsten MUELLER, Pascal KOPPERSCHMIDT, Andreas MAIERHOFER, Alfred GAGEL, Gerhard WIESEN, Liubov SMYSLOVA
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Publication number: 20210138134Abstract: The present invention relates to a dialysis machine that is configured to be equipped with an extracorporeal blood system comprising a dialysis solution system that is configured to be equipped with a dialyzer, wherein a mixing region, in particular a mixing chamber, is provided in which the fresh dialysis solution or a component thereof is located in the operation of the dialysis machine, with a concentrate line being in fluid communication with the mixing region, through which concentrate line concentrate can be conducted from a concentrate container into the mixing region, wherein at least two electrically conductive elements are arranged spaced apart from one another in or at the concentrate line or lines; that a measuring device is provided which is electrically connected to the conductive elements and which is configured to measure the conductance or a value correlated therewith between them; and that a control unit is provided which is configured to compare the measured value with a desired value, withType: ApplicationFiled: March 26, 2019Publication date: May 13, 2021Applicant: Fresenius Medical Care Deutschland GmbHInventors: Tobias IRRGANG, Tilman STÄBLEIN, Alfred GAGEL, Peter KLÖFFEL
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Patent number: 11000638Abstract: The present invention relates to a method of monitoring the bicarbonate content and the sodium content of a dialysis solution, wherein the dialysis solution is prepared while adding a bicarbonate component and an acidic sodium component, and wherein the method comprises the following steps: a. adding the acidic sodium component and measuring the conductivity (LFist,Na); b. adding the bicarbonate component and measuring the increase in conductivity (?LFist,BiC) caused by adding the bicarbonate component; c. determining the increase in conductivity (?LFexp,Bic) expected due to the addition of the bicarbonate component; d. checking whether the measured increase in conductivity (?LFist,Bic) lies in an expected range of the increase in conductivity (?LFexp,Bic); e. determining the total conductivity (LFexp,D) expected after the addition of the bicarbonate component and of the acidic sodium component; f.Type: GrantFiled: August 3, 2017Date of Patent: May 11, 2021Assignee: Fresenius Medical Care Deutschland GmbHInventors: Alfred Gagel, Tilman Stablein, Jochen Popp
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Patent number: 10967114Abstract: A dialysis machine has a blood circuit, a blood pump, a dialyzer, a venous pressure sensor, a substituate line, and a control unit. The control unit can operate the blood pump in a first operating mode and in a special operating mode, and start the special operating mode after a trigger event. In the special operating mode, a blood pump conveying rate is controlled via a default value or regulated to a desired value, with the default or desired value being derived from a value determined before the started special mode or corresponding to the value. The presence of an obstacle is polled before the special mode, and depending on the presence thereof, the start of the special mode is blocked or delayed and/or the selection of the default value or the desired value on the presence of the obstacle differs from the selection without the presence of the obstacle.Type: GrantFiled: September 25, 2015Date of Patent: April 6, 2021Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alfred Gagel, Pascal Kopperschmidt, Thomas Nuernberger
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Patent number: 10940258Abstract: A dialysis device having an extracorporeal blood circuit which has an arterial line having a blood pump and an arterial needle for connection to a patient, a venous line having a venous needle for connection to a patient and a dialyzer arranged between the arterial line and the venous line and having a blood chamber and a dialysis fluid chamber is provided. The dialysis device furthermore has a control unit and an extracorporeal blood pressure sensor which is arranged at the suction side of the blood pump. The control unit is configured such that a signal output takes place which indicates the presence of recirculation when a change in the signal of the sensor following a trigger event exceeds a threshold value.Type: GrantFiled: December 23, 2016Date of Patent: March 9, 2021Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Pascal Kopperschmidt, Alfred Gagel
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Patent number: 10881776Abstract: The invention relates to a control unit (30) for detecting an overshoot of a first limit value (G1) of a first blood concentration (B1) in a first portion (17a) of a dialysate discharge line (17) downstream of a dialysate chamber (7) of a dialyser (4) of a blood treatment device and upstream of a node point (110) at which a bypass line (100) bypassing the dialyser (4) leads into the dialysate discharge line (17), wherein the bypass line (100) branches off, upstream of the dialysate chamber (7), from a dialysate supply line (15) suitable for supplying dialysate from a dialysate source (16) to the dialysate chamber (7).Type: GrantFiled: June 28, 2017Date of Patent: January 5, 2021Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventor: Alfred Gagel
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Patent number: 10569001Abstract: The invention relates to a method and to a device for determining an optimum dialysate flow Qdopt for an extracorporeal blood treatment and to a blood treatment device comprising a device 18 for determining an optimum dialysate flow Qdopt. The optimum dialysate flow Qdopt is determined on the basis of a relationship describing the dependence of the clearance K on the dialysate flow Qd. The device according to the invention comprises a measurement device 18B for measuring at least one value which is characteristic of the clearance K, a calculation and/or evaluation unit 18A of the device according to the invention being configured in such a way that the clearance K is determined on the basis of the at least one value which is characteristic of the clearance.Type: GrantFiled: July 20, 2015Date of Patent: February 25, 2020Assignee: Fresenius Medical Care Deutschland GmbHInventors: Pascal Kopperschmidt, Andreas Maierhofer, Alfred Gagel, Andreas Wupper, Ulrich Moissl
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Publication number: 20200054808Abstract: A diagnosis method for a conductivity sensor for a dialysis fluid preparation apparatus and personal dialysis apparatus, that mix water, an A fluid and a B fluid in predetermined proportions respectively to prepare a dialysis fluid and measures the concentration of the prepared dialysis fluid by concentration measurement means is described. The diagnosis method and the respective apparatus is based in measuring the A fluid without the B fluid being present in the solution.Type: ApplicationFiled: January 3, 2018Publication date: February 20, 2020Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alfred GAGEL, Tilman STAEBLEIN
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Publication number: 20190255241Abstract: The invention relates to a control unit (30) for detecting an overshoot of a first limit value (G1) of a first blood concentration (B1) in a first portion (17a) of a dialysate discharge line (17) downstream of a dialysate chamber (7) of a dialyser (4) of a blood treatment device and upstream of a node point (110) at which a bypass line (100) bypassing the dialyser (4) leads into the dialysate discharge line (17), wherein the bypass line (100) branches off, upstream of the dialysate chamber (7), from a dialysate supply line (15) suitable for supplying dialysate from a dialysate source (16) to the dialysate chamber (7).Type: ApplicationFiled: June 28, 2017Publication date: August 22, 2019Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventor: Alfred GAGEL
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Patent number: 10322219Abstract: The present invention relates to a method of determining the pressure or of a parameter correlated with the pressure in an extracorporeal circuit of a blood treatment apparatus, in particular of a dialyzer, wherein at least one blood pump which is driven by at least one motor is located in the blood circuit, wherein the motor current of the named motor and the blood flow or a parameter correlated therewith is measured for determining the pressure or the parameter correlated therewith and wherein the pressure p or the parameter correlated therewith is calculated from the measured values.Type: GrantFiled: April 14, 2014Date of Patent: June 18, 2019Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Alfred Gagel, Benedict Glaser, Haitham Ibrahim, Pascal Kopperschmidt
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Publication number: 20190167879Abstract: The present invention relates to a method of monitoring the bicarbonate content and the sodium content of a dialysis solution, wherein the dialysis solution is prepared while adding a bicarbonate component and an acidic sodium component, and wherein the method comprises the following steps: a. adding the acidic sodium component and measuring the conductivity (LFist,Na); b. adding the bicarbonate component and measuring the increase in conductivity (?LFist,BiC) caused by adding the bicarbonate component; c. determining the increase in conductivity (?LFexp,Bic) expected due to the addition of the bicarbonate component; d. checking whether the measured increase in conductivity (?LFist,Bic) lies in an expected range of the increase in conductivity (?LFexp,Bic); e. determining the total conductivity (LFexp,D) expected after the addition of the bicarbonate component and of the acidic sodium component; f.Type: ApplicationFiled: August 3, 2017Publication date: June 6, 2019Inventors: Alfred GAGEL, Tilman STABLEIN, Jochen POPP
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Publication number: 20190160218Abstract: The present invention relates to a dialysis machine having an extracorporeal blood circuit; a dialyzer; and a dialysate circuit, wherein a blood pump is arranged in the extracorporeal blood circuit; wherein the dialyzer has a dialysate membrane which separates its blood side from its dialysate side; wherein the dialysis machine has a control unit which is configured to carry out a conditioning cycle which comprises a conditioning phase in which an ultrafiltration rate exceeds the blood flow through the dialyzer conveyed by the blood pump.Type: ApplicationFiled: July 18, 2017Publication date: May 30, 2019Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Reiner SPICKERMANN, Alfred GAGEL
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Publication number: 20190083694Abstract: The invention relates to dialysis device having an extracorporeal blood circuit which has an arterial line having a blood pump and an arterial needle for connection to a patient, a venous line having a venous needle for connection to a patient and a dialyzer arranged between the arterial line and the venous line and having a blood chamber and a dialysis fluid chamber, wherein the dialysis device furthermore has a control unit, wherein the dialysis device furthermore has an extracorporeal blood pressure sensor which is arranged at the suction side of the blood pump and wherein the control unit is configured such that a signal output takes place which indicates the presence of recirculation when a change in the signal of the sensor following a trigger event exceeds a threshold value.Type: ApplicationFiled: December 23, 2016Publication date: March 21, 2019Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Pascal KOPPERSCHMIDT, Alfred GAGEL
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Patent number: 10155077Abstract: A dialysis machine has at least one filter for the filtration of dialysis liquid and a device for determining calcification of the dialysis machine. The device has one or more sensors configured and arranged to detect either downstream, or upstream and downstream, of the at least one filter an ion concentration or a parameter representative of the ion concentration or of its change of the dialysis liquid, of a solution serving the decalcification or of another measuring solution. The device for determining the calcification of the dialysis machine has an evaluation or calcification unit configured to determine the calcification of the dialysis machine based on the ion concentration or parameter value detected by the sensor or sensors.Type: GrantFiled: November 17, 2014Date of Patent: December 18, 2018Assignee: Fresenius Medical Care Deutschland GmbHInventors: Andreas Maierhofer, Alfred Gagel, Malte Gross, Michael Koch