Patents by Inventor Alfred Hansel

Alfred Hansel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIAGNOSIS AND RISK DETERMINATION FOR HEAD AND NECK CANCER
    Publication number: 20240229146
    Abstract: Methods for the determination of the risk for developing a head and neck cancer are described. The method is based on the determination of the methylation status of genomic DNA sequences located between the genes ZNF823 and ZNF833, wherein when the sequences are methylated the risk for developing a head and neck cancer is increased.
    Type: Application
    Filed: February 26, 2021
    Publication date: July 11, 2024
    Inventors: Orlando GUNTINAS-LICHIUS, Daniel STEINBACH, Martina SCHMITZ, Alfred HANSEL
  • DIAGNOSIS AND RISK DETERMINATION FOR HEAD AND NECK CANCER
    Publication number: 20240132968
    Abstract: Methods for the determination of the risk for developing a head and neck cancer are described. The method is based on the determination of the methylation status of genomic DNA sequences located between the genes ZNF823 and ZNF833, wherein when the sequences are methylated the risk for developing a head and neck cancer is increased.
    Type: Application
    Filed: February 26, 2021
    Publication date: April 25, 2024
    Inventors: Orlando GUNTINAS-LICHIUS, Daniel STEINBACH, Martina SCHMITZ, Alfred HANSEL
  • RISK DETERMINATION FOR NEOPLASIA AND CANCER
    Publication number: 20200216911
    Abstract: Methods for the determination of the risk of developing neoplasia in a tissue, preferably anogenital tissue, showing no histopathological indications of neoplasia are described. The method is based on the determination of the methylation status of genomic DNA sequences associated with the genes ZNF671, ZNF154, ZNF776, ASTN1, BRINP2, DLX1, METAP1D and/or DLX2.
    Type: Application
    Filed: September 29, 2017
    Publication date: July 9, 2020
    Inventors: Matthias Durst, Ingo B. Runnebaum, Martina Schmitz, Alfred Hansel
  • Method for early diagnosis of carcinomas of the anogenital tract
    Patent number: 9228238
    Abstract: A method for the early diagnosis of carcinomas of the anogenital tract, preferably of the cervical carcinoma, and the preliminary stages thereof is described. The method is based on the determination of the methylation status of segments of the gene regions of ASTN1 (astrotactin 1) and ZNF671 (zinc finger protein 671, transcription factor). A DNA methylation in the promoter region or the 5?-region of these genes is indicative for carcinomas of the anogenital tract or severe preliminary stages thereof. The present invention also relates to kits which permit the conduction of the diagnostic method according to the invention.
    Type: Grant
    Filed: August 29, 2013
    Date of Patent: January 5, 2016
    Assignee: ONCGNOSTICS GMBH
    Inventors: Matthias Dürst, Alfred Hansel, Daniel Steinbach
  • METHOD FOR EARLY DIAGNOSIS OF CARCINOMAS OF THE ANOGENITAL TRACT
    Publication number: 20130344479
    Abstract: A method for the early diagnosis of carcinomas of the anogenital tract, preferably of the cervical carcinoma, and the preliminary stages thereof is described. The method is based on the determination of the methylation status of segments of the gene regions of ASTN1 (astrotactin 1) and ZNF671 (zinc finger protein 671, transcription factor). A DNA methylation in the promoter region or the 5?-region of these genes is indicative for carcinomas of the anogenital tract or severe preliminary stages thereof. The present invention also relates to kits which permit the conduction of the diagnostic method according to the invention.
    Type: Application
    Filed: August 29, 2013
    Publication date: December 26, 2013
    Applicant: Oncgnostics GmbH
    Inventors: Matthias DÜRST, Alfred HANSEL, Daniel STEINBACH
  • Method for early diagnosis of carcinomas of the anogenital tract
    Patent number: 8575326
    Abstract: A method for the early diagnosis of carcinomas of the anogenital tract, preferably of the cervical carcinoma, and the preliminary stages thereof is described. The method is based on the determination of the methylation status of segments of the gene regions of ASTN1 (astrotactin 1) and ZNF671 (zinc finger protein 671, transcription factor). A DNA methylation in the promoter region or the 5?-region of these genes is indicative for carcinomas of the anogenital tract or severe preliminary stages thereof. The present invention also relates to kits which permit the conduction of the diagnostic method according to the invention.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: November 5, 2013
    Assignee: Oncgnostics GmbH
    Inventors: Matthias Dürst, Alfred Hansel, Daniel Steinbach
  • METHOD FOR EARLY DIAGNOSIS OF CARCINOMAS OF THE ANOGENITAL TRACT
    Publication number: 20120208180
    Abstract: A method for the early diagnosis of carcinomas of the anogenital tract, preferably of the cervical carcinoma, and the preliminary stages thereof is described. The method is based on the determination of the methylation status of segments of the gene regions of ASTN1 (astrotactin 1) and ZNF671 (zinc finger protein 671, transcription factor). A DNA methylation in the promoter region or the 5?-region of these genes is indicative for carcinomas of the anogenital tract or severe preliminary stages thereof.
    Type: Application
    Filed: September 17, 2010
    Publication date: August 16, 2012
    Inventors: Matthias Dürst, Alfred Hansel, Daniel Steinbach