Patents by Inventor Alihussein N. Dohadwalla

Alihussein N. Dohadwalla has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5252598
    Abstract: The present invention relates to labdane-derivatives of the formula ##STR1## a process for their preparation and the use of these substances as medicaments, preferably as medicaments having a positive ionotropic effect, an effect of lowering intraocular pressure and lowing blood pressure.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: October 12, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Yatendra Khandelwal, Greta Moraes, Bansi Lal, Vijay A. Aroskar, Alihussein N. Dohadwalla, Richard H. Rupp
  • Patent number: 5206241
    Abstract: Labdanes of the formula ##STR1## a process for their manufacture, pharmaceutical preparations containing an effective amount of these compounds and their use for the manufacture of a pharmaceutical preparation for treatment of cardiovascular diseases and high intraocular pressure.
    Type: Grant
    Filed: March 14, 1991
    Date of Patent: April 27, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Yatendra Khandelwal, Rajeshwari Kannan, Bansi Lal, Ramanujam Rajagopalan, Vijay A. Aroskar, deceased AliHussein N. Dohadwalla, Rashida A. Dohadwalla, Anis S. Dohadwalla, Samina A. Dohadwalla, Richard H. Rupp
  • Patent number: 5141942
    Abstract: Pharmaceutical compositions comprising labdane diterpenoid derivatives and pyrimido(6,1-a)-isoquinolin-4-one derivatives when administered to the skin of a mammal or of the man increase the rate of terminal hair growth, stimulate the conversion of vellus hair to growth as terminal hair and arrest hair loss. They can be used for the treatment of several kinds of alopecia.
    Type: Grant
    Filed: November 17, 1989
    Date of Patent: August 25, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Jurgen Blumbach, Alihussein N. Dohadwalla, Noel J. de Souza
  • Patent number: 5093331
    Abstract: The present invention relates to polyoxygenated labdane-derivatives of the formula ##STR1## a process for their preparation and the use of these substances as medicaments, preferably as medicaments having a positive inotropic effect, an effect of lowering intraocular pressure and lowering blood pressure.
    Type: Grant
    Filed: October 9, 1990
    Date of Patent: March 3, 1992
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Ashok K. Gangopadbya, Alihussein N. Dohadwalla, Ramanujam Rajgopalan, Richard H. Rupp
  • Patent number: 4900727
    Abstract: The present invention relates to novel 4H-1-benzopyran-4-one derivatives, to processes for the preparation thereof and to their use as anti-inflammatory, analgesic, immuno-suppressive and anti-allergic agents. In particular, the present invention relates to novel compounds of the formula I, ##STR1## in which R.sub.1 is hydrogen, alkyl having 1 to 6 carbon atoms, arly-C.sub.1 -C.sub.4 -alkyl, substituted C.sub.1 -C.sub.6 -alkyl, C.sub.3 -C.sub.6 -cycloalkyl, C.sub.3 -C.sub.6 -cycloalkyl-C.sub.1 -C.sub.4 -alkyl, C.sub.2 -C.sub.6 -alkenyl, C.sub.3 -C.sub.6 -alkynyl, aryl or carboxyl or an aldehyde or COO--C.sub.1 -C.sub.4 -alkyl group, R.sub.2 is hydrogen, alkyl having 1 to 6 carbon atoms, nitro, amino, di-C.sub.1 -C.sub.4 -alkylamino or a halogen, R.sub.3 is C.sub.1 -C.sub.4 -alkyl, substituted C.sub.1 -C.sub.4 -alkyl, hydroxyl, C.sub.1 -C.sub.4 -alkoxy, aryl-C.sub.1 -C.sub.4 -alkyl, nitro, amino, a C.sub.1 -C.sub.4 -alkylamino or di-C.sub.1 -C.sub.4 -alkylamino group or halogen, R.sub.
    Type: Grant
    Filed: January 26, 1989
    Date of Patent: February 13, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Samba L. Kattige, Ramchandra G. Naik, Aftab D. Lakdawalla, Alihussein N. Dohadwalla, Richard H. Rupp, Noel J. de Souza
  • Patent number: 4724238
    Abstract: The present invention relates to a process for the isolation of labdan derivatives from the plant Coleus forskohlii, and their use as medicaments having anti-inflammatory and analgesic activity.
    Type: Grant
    Filed: April 3, 1986
    Date of Patent: February 9, 1988
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Alihussein N. Dohadwalla, Sadashiv S. Mandrekar, Nandkumar K. Dadkar, Yatendra Khandelwal, Richard H. Rupp, Noel J. de Souza
  • Patent number: 4603137
    Abstract: The present invention relates to a compound of the formula ##STR1## and to a process for its isolation from plants of the family comprising the meliaceae. The compound has, in particular, immunosuppressive properties, and can therefore be used as a medicament.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: July 29, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Sujata V. Bhat, Virbala Shah, Alihussein N. Dohadwalla, Sadashiv M. Mandrekar, Noel J. de Souza, Gerhard Dickneite, Roland Kurrle, Hans-Ulrich Schorlemmer, Hans-Harald Sedlacek
  • Patent number: 4598148
    Abstract: What are disclosed are pyrimido(6,1-a)isoquinolin-4-one compounds useful as hypotensive agents, bronchodilators, and anti-allergenics, intermediates useful in their preparation, and method for making the compounds and intermediates.
    Type: Grant
    Filed: September 19, 1984
    Date of Patent: July 1, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Horst Dornauer, Bani K. Bhattacharya, Alihussein N. Dohadwalla, Noel J. de Souza
  • Patent number: 4590197
    Abstract: 9,10-substituted-2-mesitylimino-3-alkyl-3,4,6,7-tetrahydro-2H-pyrimido-(6,1 -a)isoquinoline-4-ones and salts thereof having hypotensive and vasodilating properties.
    Type: Grant
    Filed: May 7, 1984
    Date of Patent: May 20, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Alihussein N. Dohadwalla, Vijay A. Aroskar, Nandkumar K. Dadkar, Horst Dornauer, Julius Mascarenhas, Noel J. deSouza
  • Patent number: 4578399
    Abstract: The possibility of using the diterpene derivative forskolin (1.alpha., 6.beta., 9.alpha.-trihydroxy-7.beta.-acetoxy-8,13-epoxy-14-labden-11-one) to increase the immunological responsiveness of mammals is described.
    Type: Grant
    Filed: April 24, 1984
    Date of Patent: March 25, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Ulrich Schorlemmer, Gerhard Dickneite, Hans-Harald Sedlacek, Noel J. de Souza, Alihussein N. Dohadwalla
  • Patent number: 4482556
    Abstract: What are disclosed are pyrimido (6,1-a)isoquinolin-4-one compounds useful as hypotensive agents, bronchodilators, and anti-allergenics, intermediates useful in their preparation, and methods for making the compounds and intermediates.
    Type: Grant
    Filed: March 26, 1980
    Date of Patent: November 13, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Horst Dornauer, Bani K. Bhattacharya, Alihussein N. Dohadwalla, Noel J. de Souza
  • Patent number: 4479948
    Abstract: Hypotensively active triazino-(2,1-a)isoquinoline compounds having the ring system ##STR1## and methods of making and using such compounds.
    Type: Grant
    Filed: July 8, 1982
    Date of Patent: October 30, 1984
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bansi Lal, Adolf D'Sa, Alihussein N. Dohadwalla, Noel J. de Souza, Horst Dornauer