Patents by Inventor Allen Lawrence Garner

Allen Lawrence Garner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240066128
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Application
    Filed: October 19, 2023
    Publication date: February 29, 2024
    Inventors: Allen Lawrence GARNER, Ram Anand VADLAMANI, David Alan DETWILER
  • Patent number: 11844835
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Grant
    Filed: August 30, 2021
    Date of Patent: December 19, 2023
    Assignees: PURDUE RESEARCH FOUNDATION, NANOVIS, LLC
    Inventors: Allen Lawrence Garner, Ram Anand Vadlamani, David Alan Detwiler
  • Publication number: 20230013598
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Application
    Filed: September 28, 2022
    Publication date: January 19, 2023
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Duh-Lan Lee, Allen Lawrence Garner
  • Patent number: 11525768
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Grant
    Filed: August 12, 2019
    Date of Patent: December 13, 2022
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Patent number: 11464829
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: October 11, 2022
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
  • Publication number: 20220047704
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Application
    Filed: August 30, 2021
    Publication date: February 17, 2022
    Inventors: Allen Lawrence GARNER, Ram Anand VADLAMANI, David Alan DETWILER
  • Patent number: 11123428
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: September 21, 2021
    Assignees: Purdue Research Foundation, Nanovis, LLC
    Inventors: Allen Lawrence Garner, Ram Anand Vadlamani, David Alan Detwiler
  • Publication number: 20200368351
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 26, 2020
    Applicants: Purdue Research Foundation, Nanovis, Inc.
    Inventors: Allen Lawrence Garner, Ram Anand Vadlamani, David Alan Detwiler
  • Publication number: 20190359970
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Application
    Filed: August 12, 2019
    Publication date: November 28, 2019
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Publication number: 20190336578
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Application
    Filed: July 17, 2019
    Publication date: November 7, 2019
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
  • Patent number: 10421956
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: September 24, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Patent number: 10383915
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: August 20, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
  • Patent number: 10369200
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: August 6, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
  • Patent number: 10329551
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: June 25, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Publication number: 20180237764
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Application
    Filed: April 17, 2018
    Publication date: August 23, 2018
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Publication number: 20170314009
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Application
    Filed: July 17, 2017
    Publication date: November 2, 2017
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Patent number: 9708597
    Abstract: In accordance with the present disclosure, exposure of a sample to one or more electric pulses via capacitive coupling is described. In certain embodiments, the sample may be a biological sample to be treated or modified using the pulsed electric fields. In certain embodiments, the electric pulses may be delivered to a load using capacitive coupling. In other embodiments, the electric pulses may be bipolar pulses.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: July 18, 2017
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Antonio Caiafa, Vasile Bogdan Neculaes, Allen Lawrence Garner, Andrew Soliz Torres
  • Publication number: 20160367633
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Application
    Filed: August 30, 2016
    Publication date: December 22, 2016
    Inventors: VASILE BOGDAN NECULAES, ANDREW SOLIZ TORRES, ANTONIO CAIAFA, BRIAN DUN-LAN LEE, ALLEN LAWRENCE GARNER
  • Publication number: 20160367632
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Application
    Filed: August 30, 2016
    Publication date: December 22, 2016
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Dun-Lan Lee, Allen Lawrence Garner
  • Patent number: 9452199
    Abstract: Methods and systems for releasing growth factors are disclosed. In certain embodiments, a blood sample is exposed to a sequence of one or more electric pulses to trigger release of a growth factor in the sample. In certain embodiments, the growth factor release is not accompanied by clotting within the blood sample.
    Type: Grant
    Filed: January 17, 2014
    Date of Patent: September 27, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Vasile Bogdan Neculaes, Andrew Soliz Torres, Antonio Caiafa, Brian Duh-Lan Lee, Allen Lawrence Garner