Patents by Inventor Amarpreet S. Sawhney

Amarpreet S. Sawhney has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11324828
    Abstract: Some aspects of this disclosure relate to a method of treating an ophthalmic disease affecting an eye of a patient comprising forming a covalently-crosslinked hydrogel for controlled release of a therapeutic agent.
    Type: Grant
    Filed: February 20, 2019
    Date of Patent: May 10, 2022
    Assignee: Incept, LLC
    Inventors: Amarpreet S. Sawhney, William H. Ransone, II
  • Publication number: 20220125954
    Abstract: Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.
    Type: Application
    Filed: January 7, 2022
    Publication date: April 28, 2022
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Publication number: 20220096711
    Abstract: Disclosed are methods, devices and materials for the in situ formation of a nerve cap and/or a nerve wrap to inhibit neuroma formation following planned or traumatic nerve injury. The method includes the steps of identifying a severed end of a nerve, and positioning the severed end into a cavity defined by a form. A transformable media is introduced into the form cavity to surround the severed end. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the severed end. The media may be a hydrogel, and the transformation may produce a synthetic crosslinked hydrogel protective barrier.
    Type: Application
    Filed: December 10, 2021
    Publication date: March 31, 2022
    Inventors: Corinne Bright, Yong Ren, Kenneth M. Martin, Farhad Khosravi, Amarpreet S. Sawhney
  • Publication number: 20220054705
    Abstract: Disclosed are methods, devices and materials for the in situ formation of a nerve cap and/or a nerve wrap to inhibit neuroma formation following planned or traumatic nerve injury. The method includes the steps of identifying a severed end of a nerve, and positioning the severed end into a cavity defined by a form. A transformable media is introduced into the form cavity to surround the severed end. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the severed end. The media may be a hydrogel, and the transformation may produce a synthetic crosslinked hydrogel protective barrier.
    Type: Application
    Filed: September 17, 2021
    Publication date: February 24, 2022
    Inventors: Corinne Bright, Yong Ren, Kenneth M. Martin, Farhad Khosravi, Amarpreet S. Sawhney
  • Publication number: 20210361292
    Abstract: Disclosed are methods, devices and materials for the in situ formation of an implant for treating a nerve. A treatment site on a nerve is positioned within a cavity defined by a form. A transformable media is introduced into the form cavity to surround the treatment site. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the treatment site. The implant may be a growth inhibiting nerve cap to inhibit neuroma formation following planned or traumatic nerve injury, a growth permissive conduit for facilitating reconnection of a severed nerve, or an anchor for stabilizing a pain management electrode with respect to a nerve. Access to the nerve treatment site may be open surgical or percutaneous.
    Type: Application
    Filed: July 29, 2021
    Publication date: November 25, 2021
    Inventors: Corinne Bright, Yong Ren, Ken Martin, Farhad Khosravi, Amarpreet S. Sawhney
  • Patent number: 11160883
    Abstract: Implantable materials visible under ultrasound may be delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: November 2, 2021
    Assignee: Incept, LLC
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Patent number: 11154624
    Abstract: Implantable materials visible under ultrasound may be delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: October 26, 2021
    Assignee: Incept, LLC
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Publication number: 20210315587
    Abstract: Disclosed are methods, devices and materials for the in situ formation of an implant for treating a nerve. A treatment site on a nerve is positioned within a cavity defined by a form. A transformable media is introduced into the form cavity to surround the treatment site. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the treatment site. A hydrophilic characteristic of the media cooperates with a hydrophobic characteristic of the surface of the cavity to facilitate a rapid release of the implant from the cavity following the transformation. The implant may be a growth inhibiting nerve cap to inhibit neuroma formation following planned or traumatic nerve injury, a growth permissive conduit for facilitating reconnection of a severed nerve, or an anchor for stabilizing a pain management electrode with respect to a nerve.
    Type: Application
    Filed: January 13, 2021
    Publication date: October 14, 2021
    Inventors: Corinne Bright, Yong Ren, Ken Martin, Farhad Khosravi, Amarpreet S. Sawhney
  • Publication number: 20210268141
    Abstract: Methods are provided for making freeze dried hydrogel and structures therefrom that may be introduced into a patient's body for medical applications. Precursor components are combined to initiate crosslinking. The combined precursor components are placed in a chilled tray, and allowed to crosslink to a desired level of complete crosslinking before and/or after being placed onto the tray. The partially crosslinked hydrogel is frozen and freeze dried. After freeze drying, the hydrogel is conditioned to substantially complete crosslinking, and formed into one or more structures, e.g., plugs, hemostatic, or other medical devices. For example, the hydrogel may be cut, machined, rolled, folded, compressed, and/or cored into that may be loaded into delivery devices that may be introduced into a body to implant or otherwise deliver the structures into the body, e.g., to seal a puncture or other passage through tissue.
    Type: Application
    Filed: February 12, 2021
    Publication date: September 2, 2021
    Inventors: Amarpreet S. Sawhney, Steven L. Bennett, Suresh S. Pai, Scott R. Sershen, Fred H. Co
  • Patent number: 11083802
    Abstract: Implantable materials visible under ultrasound may delivered to a selected placement site and biodegrade after a certain period of time. Ultrasound visible implantable materials may be delivered through an applicator and may include ultrasound contrast agents and/or radiopaque agents. Applications include monitoring the delivery of an implant of the implantable materials to the placement site with ultrasound and delivery of therapeutic agents to a tissue at the placement site for treating a patient.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: August 10, 2021
    Assignee: Incept, LLC
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Publication number: 20210187160
    Abstract: Disclosed are methods, devices and materials for the in situ formation of a nerve cap to inhibit neuroma formation following planned or traumatic nerve injury. The method includes the steps of identifying a severed end of a nerve, and positioning the severed end into a cavity defined by a form. A transformable media is introduced into the form cavity to surround the severed end. The media is permitted to undergo a transformation from a first, relatively flowable state to a second, relatively non flowable state to form a protective barrier surrounding the severed end. The media may be a hydrogel, and the transformation may produce a synthetic crosslinked hydrogel protective barrier.
    Type: Application
    Filed: December 30, 2020
    Publication date: June 24, 2021
    Inventors: Corinne BRIGHT, Yong REN, Kenneth M. MARTIN, Farhad KHOSRAVI, Amarpreet S. SAWHNEY
  • Publication number: 20210177975
    Abstract: Serial-solvent biomaterials are described. Embodiments include materials made in an organic solvent that are stripped of the solvent and used in a patient, where they imbibe water and form a hydrogel. These materials are useful for, among other things, delivering therapeutic agents, tissue augmentation, and radiological marking.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 17, 2021
    Inventors: Peter Jarrett, Rami El-Hayek, Amarpreet S. Sawhney
  • Publication number: 20210128478
    Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.
    Type: Application
    Filed: August 21, 2020
    Publication date: May 6, 2021
    Inventors: Peter Jarrett, Michael J. McGrath, Timothy S. Jarrett, Rami El-Hayek, Andrew C. Vanslette, Courtney A. Rosales, Charles D. Blizzard, Amarpreet S. Sawhney
  • Publication number: 20210077299
    Abstract: A prosthesis comprising a water-dissolvable coating. A prosthesis for a lacrimal canaliculus comprising a swellable punctal plug with a proximal end and a distal end, with the plug comprising a water-dissolvable biocompatible coating on the distal and/or the proximal end. Materials and methods for making and using the same. A prosthesis for placement in or across natural or prosthetic lumens, ostia, ducts, sinus, or sphincters, the prosthesis comprising a coating. The prosthesis can further provide a depot for sustained drug delivery to tissue.
    Type: Application
    Filed: March 3, 2020
    Publication date: March 18, 2021
    Inventors: Peter Jarrett, Amarpreet S. Sawhney, Michael J. McGrath, Arthur Driscoll, Ankita D. Desai, Michael Bassett
  • Publication number: 20210069353
    Abstract: Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.
    Type: Application
    Filed: August 21, 2020
    Publication date: March 11, 2021
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Patent number: 10940231
    Abstract: Methods are provided for making freeze dried hydrogel and structures therefrom that may be introduced into a patient's body for medical applications. Precursor components are combined to initiate crosslinking. The combined precursor components are placed in a chilled tray, and allowed to crosslink to a desired level of complete crosslinking before and/or after being placed onto the tray. The partially crosslinked hydrogel is frozen and freeze dried. After freeze drying, the hydrogel is conditioned to substantially complete crosslinking, and formed into one or more structures, e.g., plugs, hemostatic, or other medical devices. For example, the hydrogel may be cut, machined, rolled, folded, compressed, and/or cored into that may be loaded into delivery devices that may be introduced into a body to implant or otherwise deliver the structures into the body, e.g., to seal a puncture or other passage through tissue.
    Type: Grant
    Filed: July 9, 2014
    Date of Patent: March 9, 2021
    Assignee: Incept, LLC
    Inventors: Amarpreet S. Sawhney, Steven L. Bennett, Suresh S. Pai, Scott R. Sershen, Fred H. Co
  • Patent number: 10905765
    Abstract: Serial-solvent biomaterials are described. Embodiments include materials made in an organic solvent that are stripped of the solvent and used in a patient, where they imbibe water and form a hydrogel. These materials are useful for, among other things, delivering therapeutic agents, tissue augmentation, and radiological marking.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: February 2, 2021
    Assignee: Incept, LLC
    Inventors: Peter Jarrett, Rami El-Hayek, Amarpreet S. Sawhney
  • Publication number: 20200368402
    Abstract: Use of embolic material that is biodegradable provides for embolizing a hypervascular vessel formed in response to chronic inflammation in a musculoskeletal vasculature or a vessel related to production of ghrelin. The embolic material is biodegradable within a predetermined period of time. Medical systems are configured for delivery of embolic material for embolizing the hypervascular vessel or the vessel related to production of ghrelin.
    Type: Application
    Filed: May 8, 2020
    Publication date: November 26, 2020
    Inventors: Amarpreet S. Sawhney, Timothy S. Jarrett, Hans Claesson
  • Patent number: 10786581
    Abstract: Implantable materials may be used in an iatrogenic site. Applications include radioopaque materials for fiducial marking.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: September 29, 2020
    Assignee: Incept, LLC
    Inventors: Patrick Campbell, Amarpreet S. Sawhney
  • Patent number: 10786462
    Abstract: Drug delivery using bio-affecting drugs, particularly with shape changing drug delivery devices. Embodiments are included for depots for delivery of a therapeutic agent that change from an elongated state ex vivo to a coil in vivo where the agent is released.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: September 29, 2020
    Assignee: Incept, LLC
    Inventors: Peter Jarrett, Michael J. McGrath, Timothy S. Jarrett, Rami El-Hayek, Andrew C. Vanslette, Courtney A. Rosales, Charles D. Blizzard, Amarpreet S. Sawhney