Patents by Inventor Amy K. Roshak

Amy K. Roshak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nf-kb inhibitors
    Publication number: 20040024047
    Abstract: The present invention provides novel compounds and methods for treating diseases with aminothiophene inhibitors of IKK-&bgr; phosphorylation of I&kgr;B.
    Type: Application
    Filed: April 10, 2003
    Publication date: February 5, 2004
    Inventors: James F. Callahan, Amy K. Roshak
  • Nf-kb inhibitors
    Publication number: 20040006118
    Abstract: The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-&bgr; phosphorylation of I&kgr;B.
    Type: Application
    Filed: April 10, 2003
    Publication date: January 8, 2004
    Inventors: James F Callahan, Amy K Roshak
  • Tumor necrosis factor related receptor, TR6
    Patent number: 6313269
    Abstract: TR6 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR6 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (e.g. inflammatory bowel disease, psoriasis), transplant rejection, graft vs. host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, Bone diseases, cancer, atheroschlerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: November 6, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Keith C. Deen, Peter R. Young, Lisa A. Marshall, Amy K. Roshak, Kong B. Tan, Alemseged Truneh
  • Human serum inducible kinase (Snk)
    Patent number: 6245544
    Abstract: The Serum Inducible Kinase (Snk) polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Serum Inducible Kinase (Snk) polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: February 16, 2000
    Date of Patent: June 12, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Karen M Anderson, Mark M Bouzyk, Michael J Hansbury, Jeffrey R Jackson, Sandhya S Nerurkar, Amy K Roshak
  • Expression vectors and process for producing human B cell surface molecule RP105
    Patent number: 6221629
    Abstract: Nucleic acid molecules encoding a human B cell surface molecule are provided. Polypeptides and antibodies which bind to these polypeptides are also provided. In addition, methods of detecting mutated forms of the molecule are provided.
    Type: Grant
    Filed: January 14, 1998
    Date of Patent: April 24, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Lisa A. Marshall, Amy K. Roshak
  • Human serum inducible kinase (Snk)
    Patent number: 6063609
    Abstract: The Serum Inducible Kinase (Snk) polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Serum Inducible Kinase (Snk) polypeptides and polynucleotides in therapy, and diagnostic assays for such.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: May 16, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Karen M Anderson, Mark M Bouzyk, Michael J Hansbury, Jeffrey R Jackson, Sandhya S Nerurkar, Amy K Roshak
  • DNA sequence of human RP-105
    Patent number: 5780609
    Abstract: Nucleic acid molecules encoding a human B cell surface molecule are provided. Polypeptides and antibodies which bind to these polypeptides are also provided. In addition, methods of detecting mutated forms of the molecule are provided.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: July 14, 1998
    Assignee: SmithKline Beecham Corporation
    Inventors: Lisa A. Marshall, Amy K. Roshak