Patents by Inventor Ana MORAGA YEBENES

Ana MORAGA YEBENES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aptamers Specific for TLR-4 and Uses Thereof
    Publication number: 20230279402
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to a and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Application
    Filed: January 19, 2023
    Publication date: September 7, 2023
    Applicant: APTATARGETS, S.L.
    Inventors: Ignacio LIZASOAIN HERNANDEZ, Victor Manuel GONZALEZ MUÑOZ, Geronimo FERNANDEZ GOMEZ -CHACON, Maria Angeles MORO SANCHEZ, Maria Elena MARTIN PALMA, Ana MORAGA YEBENES
  • Aptamers specific for TLR-4 and uses thereof
    Patent number: 11591603
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to a and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Grant
    Filed: September 16, 2020
    Date of Patent: February 28, 2023
    Assignee: APTATARGETS, S.L.
    Inventors: Ignacio Lizasoain Hernandez, Victor Manuel Gonzalez Muñoz, Geronimo Fernandez Gomez-Chacon, Maria Angeles Moro Sanchez, Maria Elena Martin Palma, Ana Moraga Yebenes
  • APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOF
    Publication number: 20210130830
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to a and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Application
    Filed: September 16, 2020
    Publication date: May 6, 2021
    Applicant: APTATARGETS, S.L.
    Inventors: Ignacio LIZASOAIN HERNANDEZ, Victor Manuel GONZALEZ MUÑOZ, Geronimo FERNANDEZ GOMEZ-CHACON, Maria Angeles MORO SANCHEZ, Maria Elena MARTIN PALMA, Ana MORAGA YEBENES
  • Aptamers specific for TLR-4 and uses thereof
    Patent number: 10808252
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to a and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: October 20, 2020
    Assignee: APTATARGETS, S.L.
    Inventors: Ignacio Lizasoain Hernandez, Victor Manuel Gonzalez Muñoz, Geronimo Fernandez Gomez-Chacon, Maria Angeles Moro Sanchez, Maria Elena Martin Palma, Ana Moraga Yebenes
  • APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOF
    Publication number: 20190211334
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to a and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Application
    Filed: December 14, 2018
    Publication date: July 11, 2019
    Applicant: APTATARGETS, S.L.
    Inventors: Ignacio LIZASOAIN HERNANDEZ, Victor Manuel GONZALEZ MUÑOZ, Geronimo FERNANDEZ GOMEZ-CHACON, Maria Angeles MORO SANCHEZ, Maria Elena MARTIN PALMA, Ana MORAGA YEBENES
  • Aptamers specific for TLR-4 and uses thereof
    Patent number: 10196642
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: February 5, 2019
    Assignee: APTATARGETS, S.L.
    Inventors: Ignacio Lizasoain Hernandez, Victor Manuel Gonzalez Muñoz, Geronimo Fernandez Gomez-Chacon, Maria Angeles Moro Sanchez, Maria Elena Martin Palma, Ana Moraga Yebenes
  • APTAMERS SPECIFIC FOR TLR-4 AND USES THEREOF
    Publication number: 20170130227
    Abstract: The invention relates to a nucleic acid aptamer with the capability of binding specifically to and inhibiting TLR-4, to a complex comprising said aptamer and a functional group, as well as to pharmaceutical compositions thereof. The invention also relates to uses and methods for detecting TLR-4 and to uses and methods for inhibiting TLR-4. Finally, the invention also relates to an aptamer for use in manufacturing a drug for the treatment of a pathology characterized by an increase in expression of TLR4 and/or an increase in activation of TLR-4.
    Type: Application
    Filed: June 24, 2015
    Publication date: May 11, 2017
    Inventors: Ignacio LIZASOAIN HERNANDEZ, Victor Manuel GONZALEZ MUÑOZ, Geronimo FERNANDEZ GOMEZ-CHACON, Maria Angeles MORO SANCHEZ, Maria Elena MARTIN PALMA, Ana MORAGA YEBENES