Patents by Inventor André Lescarbeau

André Lescarbeau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR STEREOSELECTIVE REDUCTION
    Publication number: 20110009442
    Abstract: The invention is directed to a method to reduce a C—C double bond of an enone of a steroidal compound to produce a mixture of ? ketone product and ? ketone product, comprising treating a solution or suspension of the steroidal compound in a solvent with hydrogen gas in the presence of a catalyst and a substituted pyridine.
    Type: Application
    Filed: December 24, 2008
    Publication date: January 13, 2011
    Inventors: Brian C. Austad, Andre Lescarbeau, Lin-Chen Yu
  • Deazapurines and uses thereof
    Patent number: 7868002
    Abstract: As discussed above, there remains a need for the development of novel therapeutic agents useful for treating inflammatory or autoimmune and proliferative diseases. The present invention provides novel compounds of general formula (I), and pharmaceutical compositions thereof, as described generally and in classes and subclasses herein, as well as methods of making and using such compounds.
    Type: Grant
    Filed: September 28, 2007
    Date of Patent: January 11, 2011
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Jane Daun, Heather A. Davis, Bruce DeCosta, Fabian Gusovsky, Ieharu Hishinuma, Yimin Jiang, Toshihiko Kaneko, Kouichi Kikuchi, Seiichi Kobayashi, André Lescarbeau, Xiang-Yi Li, Kenzo Muramoto, Norihito Ohi, Marc Pesant, Boris M. Seletsky, Motohiro Soejima, Mark Spyvee, Lynda Tremblay, Ye Yao, Hiromitsu Yokohama, Yan (Janet) Zhao, Wanjun Zheng
  • Cyclopamine analogs
    Patent number: 7812164
    Abstract: The invention provides novel derivatives of cyclopamine having the following formula:
    Type: Grant
    Filed: December 27, 2007
    Date of Patent: October 12, 2010
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Brian Austad, Mark L. Behnke, Alfredo C. Castro, Michael J. Grogan, Somarajannair Janardanannair, Andre Lescarbeau, Stephane Peluso, Martin Tremblay
  • COMPOUNDS FOR PREPARING IMMUNOLOGICAL ADJUVANT
    Publication number: 20100197951
    Abstract: The present invention provides methods for preparing TLR-4 receptor agonist E6020: and stereoisomers thereof, which compounds are useful as an immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases. Also provided are synthetic intermediates useful for implementing the inventive methods.
    Type: Application
    Filed: February 2, 2010
    Publication date: August 5, 2010
    Applicant: Eisai R & D Management Co., Ltd.
    Inventors: Francis G. FANG, James E. Foy, Lynn Hawkins, Charles Lemelin, Andre Lescarbeau, Xiang Nu, Kuo-Ming Wu
  • Compounds for preparing immunological adjuvant
    Patent number: 7683200
    Abstract: The present invention provides methods for preparing TLR-4 receptor agonist E6020: and stereoisomers thereof, which compounds are useful as an immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases. Also provided are synthetic intermediates.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: March 23, 2010
    Assignee: Eisai R & D Management Co., Ltd.
    Inventors: Francis G. Fang, James E. Foy, Lynn Hawkins, Charles Lemelin, Andre Lescarbeau, Xiang Nu, Kuo-Ming Wu
  • CYCLOPAMINE ANALOGS
    Publication number: 20090216022
    Abstract: The invention provides novel derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: August 27, 2008
    Publication date: August 27, 2009
    Inventors: Brian Austad, Mark L. Behnke, Alfredo C. Castro, Andre B. Charette, Michael J. Grogan, Somarajannair Janardanannair, Andre Lescarbeau, Stephane Peluso, Martin Tremblay
  • CYCLOPAMINE ANALOGS
    Publication number: 20090012109
    Abstract: The invention provides novel derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: August 27, 2008
    Publication date: January 8, 2009
    Inventors: Brian Austad, Mark L. Behnke, Alfredo C. Castro, Andre B. Charette, Michael J. Grogan, Somarajannair Janardanannair, Andre Lescarbeau, Stephane Peluso, Martin Tremblay
  • CYCLOPAMINE ANALOGS
    Publication number: 20080293754
    Abstract: The invention provides novel derivatives of cyclopamine having the following formula:
    Type: Application
    Filed: December 27, 2007
    Publication date: November 27, 2008
    Inventors: Brian Austad, Mark L. Behnke, Alfredo C. Castro, Andre B. Charette, Michael J. Grogan, Somarajannair Janardanannair, Andre Lescarbeau, Stephane Peluso, Martin Tremblay
  • CYCLOPAMINE LACTAM ANALOGS AND METHODS OF USE THEREOF
    Publication number: 20080287420
    Abstract: The present invention relates to steroidal alkaloids useful in the treatment of hedgehog pathway related disorders, particularly cancer.
    Type: Application
    Filed: March 7, 2008
    Publication date: November 20, 2008
    Applicant: Infinity Discovery, Inc.
    Inventors: Alfredo Castro, Michael J. Grogan, Andre Lescarbeau, Martin Tremblay
  • Deazapurines and uses thereof
    Publication number: 20080103137
    Abstract: As discussed above, there remains a need for the development of novel therapeutic agents useful for treating inflammatory or autoimmune and proliferative diseases.
    Type: Application
    Filed: September 28, 2007
    Publication date: May 1, 2008
    Inventors: Jane Daun, Heather Davis, Bruce DeCosta, Fabian Gusovsky, Ieharu Hishinuma, Yimin Jiang, Toshihiko Kaneko, Kouichi Kikuchi, Seiichi Kobayashi, Andre Lescarbeau, Xiang-Yi Li, Kenzo Muramoto, Norihito Ohi, Marc Pesant, Boris Seletsky, Motohiro Soejima, Mark Spyvee, Lynda Tremblay, Ye Yao, Hiromitsu Yokohama, Yan (Janet) Zhao, Wanjun Zheng
  • Deazapurines and uses thereof
    Patent number: 7314936
    Abstract: The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: January 1, 2008
    Assignee: Eisai Co., Ltd.
    Inventors: Jane Daun, Heather A. Davis, Bruce DeCosta, Fabian Gusovsky, Ieharu Hishinuma, Yimin Jiang, Toshihiko Kaneko, Kouichi Kikuchi, Seiichi Kobayashi, André Lescarbeau, Xiang-Yi Li, Kenzo Muramoto, Norihito Ohi, Marc Pesant, Boris M. Seletsky, Motohiro Soejima, Mark Spyvee, Lynda Tremblay, Ye Yao, Hiromitsu Yokohama, Yan (Janet) Zhao, Wanjun Zheng
  • Compounds for preparing immunological adjuvant
    Publication number: 20070082875
    Abstract: The present invention provides methods for preparing TLR-4 receptor agonist E6020: and stereoisomers thereof, which compounds are useful as an immunological adjuvants when co-administered with antigens such as vaccines for bacterial and viral diseases. Also provided are synthetic intermediates.
    Type: Application
    Filed: June 30, 2006
    Publication date: April 12, 2007
    Applicant: Eisai Co., Ltd.
    Inventors: Francis Fang, James Foy, Lynn Hawkins, Charles Lemelin, Andre Lescarbeau, Xiang Niu, Kuo-Ming Wu
  • Deazapurines and uses thereof
    Publication number: 20050124649
    Abstract: The present invention provides compounds having formula (I), wherein R1, R2, R3 and n are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof in the treatment of inflammatory or autoimmune and proliferative disorders and as inhibitors of cell adhesion molecule expression and inflammatory cytokine signal transduction generally.
    Type: Application
    Filed: January 7, 2003
    Publication date: June 9, 2005
    Applicant: EISAI CO., LTD
    Inventors: Jane Daun, Heather Davis, Bruce DeAcosta, Fabian Gusovsky, Ieharu Hishinuma, Yimin Jiang, Toshihiko Kaneko, Kouichi Kikuchi, Seiichi Kobayashi, Andre Lescarbeau, Xiang-Yi Li, Kenzo Muramoto, Norihito Ohi, Marc Pesant, Boris Seletsky, Mark Spyvee, Lynda Tremblay, Ye Yao, Hiromitsu Yokohama, Yan (Janet) Zhao, Wanjun Zheng