Abstract: Disclosed herein are thermal interface materials comprising thermoset binder component and a mixture of spherically shaped and thermally conductive fillers and the use thereof in battery powered vehicles.

Abstract: A system for transporting a carrying plate may include a lifting assembly comprising a carriage, and a carrying assembly. The lifting assembly may include a carriage having one or more lifting arms configured to lift the carrying assembly at least in part by one or more carrying arms of the carrying assembly. A carrying assembly may include a perimeter frame surrounding a perimeter of a carrying plate, one or more carrying arms attached to the perimeter frame, and one or more indexing pins extending or extensible inwardly from the perimeter frame. The one or more indexing pins may detachably secure the carrying plate to the perimeter frame. A method of transporting a carrying plate may include detachably securing a carrying plate to a perimeter frame of a carrying assembly and transporting the carrying assembly with a lifting assembly.

Abstract: The invention relates to a PSMA-targeting conjugate comprising (a) an amatoxin; (b) a small molecule PSMA-targeting moiety; and (c) optionally a linker linking said amatoxin and said small molecule PSMA-targeting moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate.

Abstract: A portable power tool, in particular an angle grinder, includes a housing that accommodates a drive and an electronic device with an interface configured to electrically connect the electronic device. The power tool further includes a housing inner part that is configured as a drive housing and supports the electronic device. The interface has at least one first electrical interface contact region and at least one second interface contact region spaced apart from the first interface contact region. At least one insulating element spaced apart from the interface contact regions is arranged between the housing inner part and the electronic device. The insulating element is configured to avoid an electrical short-circuiting connection between the first interface contact region and the second interface contact region.

Abstract: Disclosed herein are thermal interface materials (TIM) composition comprising: a) a non-reactive polyurethane prepolymer; b) about 70-95 wt % of aluminum trihydroxide (ATH); c) about 0.15-1.5 wt % of at least one silane terminated urethane prepolymer; and d) about 1-20 wt % of at least one plasticizer, with the total weight of the thermal interface material totaling to 100 wt %.

Abstract: Disclosed herein are thermal interface material comprising liquid epoxy resin that is free of aromatic groups and high loading of aluminum trihydroxide and the use thereof in battery powered vehicles.

Abstract: A motor vehicle shell of a motor vehicle includes a frame structure that is formed by crossmembers and by longitudinal members. The frame structure is closed peripherally and protrudes downwardly in a vertical direction of the motor vehicle from a base element. A receiving chamber for receiving an electrical energy store is delimited by the frame structure. A cover is formed separately from the frame structure and is disposed opposite the base element. The receiving chamber is closed downwardly in the vertical direction of the motor vehicle by the cover. An annular and dimensionally stable intermediary element is formed separately from the frame structure and separately from the cover. The intermediary element is disposed between the frame structure and the cover and the intermediary element is fixed at least in a liquid-tight manner on the frame structure by a firmly bonded connection.

Abstract: Disclosed is a composition including one or more isocyanate functional prepolymers; one or more catalysts for the reaction of isocyanate moieties and active hydrogen containing moieties; one or more mercapto silanes; one or more amino silanes, isocyanato silanes or a mixture thereof; one or more reinforcing fillers comprising one or more high surface area carbon blacks; one or more untreated calcium carbonates; one or more polyisocyanates having an isocyanate functionality of about 2 or greater; and one or more linear plasticizers. Preferably, the isocyanate functional prepolymer is prepared in the presence of at least a portion of the linear plasticizer. Preferably, the isocyanate functional polymer is prepared in the presence of a dialkyl malonate. The composition may be one-part adhesive composition. Also disclosed are methods of applying the compositions to substrates.

Abstract: Provided is a waveguide arrangement, comprising a diffractive input coupling element (11), in particular a volume hologram, a diffractive output coupling element (13), in particular a volume hologram, and optionally a beam expansion element (12), in particular a volume hologram. The expansion element (12) and the output coupling element (13) expand a light beam in different directions.

Abstract: An electrical switching device is provided for interrupting an electrical connection. The device has a switching chamber and two contact pieces being arranged directly in the switching chamber or in an encapsulated housing arranged in the switching chamber and configured to be gas-tight in relation to the switching chamber. The contact pieces are movable relative to each other to bring about a switching action. A fluid insulation medium is also provided, which is arranged in the switching chamber or in a storage volume which can be connected to the switching chamber. The switching chamber or the storage volume has an outlet for letting out the fluid insulation medium. A filter is provided at or adjacent to the outlet, the filter configured to filter gaseous components of the insulation medium, or the reaction products thereof, conducted through the outlet.

Abstract: The invention relates inter alia to a combination comprising (i) a first component comprising at least one therapeutic RNA and (ii) a second component comprising at least one antagonist of at least one RNA sensing pattern recognition receptor. Further provided are compositions comprising at least one therapeutic RNA and at least one antagonist of at least one RNA sensing pattern recognition receptor. The combination of the two components is able to reduce immunostimulatory properties of the first component as well as promote expression after administration. Additionally, first and second medical uses, and methods of treating or preventing diseases, disorders or conditions are provided.

Abstract: The invention relates to a conjugate comprising (a) an amatoxin comprising (i) an amino acid 4 with a 6?-deoxy position; and (ii) an amino acid 8 with an S-deoxy position; (b) a BCMA-binding moiety comprising (i) the variable domains of humanized antibody J22.9-ISY, and (ii) a heavy chain constant region comprising a D265C mutation; and (c) a protease-cleavable linker linking said amatoxin and said target-binding moiety. The invention furthermore relates to a pharmaceutical composition comprising such conjugate, particularly for use in the treatment of multiple myeloma.

Abstract: The present invention relates to a liquid crystalline medium comprising dichroitic dyes made of benzothiadiazoles and related extended heterocyclic derivatives, the use of said medium for optical, electro-optical and electronic purposes, in particular in devices for regulating the passage of radiation energy from an outside space into an inside space, for example in windows. The invention further relates to devices containing the liquid crystalline medium according to the invention. Some new dichroitic dyes are disclosed.

Abstract: The teachings herein relate to new compositions for thermal interface materials that provide improved thermal conductivity without requiring filler materials that are expensive or abrasive. The improved thermal conductivity is achieved using a combination of increased filler loading, selection of a filler having abroad particle size distribution, and selection of filler that is non-abrasive. In order to achieve maximum thermal conductivity, the combination of the liquid matrix material and the filler preferably are chosen to avoid forming bonds between filler particles. Such bonds can also be avoided by including a surface modifier that modifies the surface of the filler particles.

Abstract: Disclosed is an adhesive system and method of use thereof wherein the adhesive composition comprises a moisture curable adhesive comprised of an isocyanate terminated prepolymer and a cure accelerator having two curatives components having different cure kinetics. The cure accelerator is comprised of an isocyanate reactive compound comprising a primary, secondary or tertiary amino group, or a primary thiol group having faster curing kinetics resulting an increase in bead stability within the first minutes and a polyol selected from a diol and/or triol with slower curing kinetics allowing for sufficient open time and yet a fast strength build up. The preferred method of application of the adhesive system is via a 1K application gun.

Abstract: The teachings herein relate to new compositions for thermal interface materials that provide improved thermal conductivity without requiring filler materials that are expensive or abrasive. The improved thermal conductivity is achieved using a combination of increased filler loading, selection of a filler having abroad particle size distribution, and selection of filler that is non-abrasive. The thermal interface material preferably has a specific gravity of about 4.0 or less, about 3.0 or less, about 2.5 or less, or about 2.4 or less. The thermal interface material may be a two-part composition. In order to achieve maximum thermal conductivity, each part preferably includes a liquid matrix material and dispersed filler. Upon mixing, the first and second parts may react to increase this viscosity (e.g., by polymerizing and/or cross-linking). The first part preferably includes a carbamate-containing compound that reacts with a carbamate-reactive compound, which is preferably in the second component.

Abstract: A device for removing hot-melt adhesive from a rotating, vertically-arranged roller (1), comprising: a hollow, preferably hollow cylindrical, scraper (2), characterized in that the scraper (2) comprises an opening (6) on the circumferential surface thereof along the longitudinal axis, at which opening a strike plate (3) that protrudes radially outward is arranged, and wherein the strike plate (3) is arranged such that it can be brought into a position for removing adhesive from the roller (1) and can convey the removed adhesive towards the circumferential inner side of the scraper (2).

Abstract: Disclosed herein are thermal interface materials comprising non-reactive polyurethane prepolymer and high loading of aluminum trihydroxide and the use thereof in battery powered vehicles.

Abstract: Disclosed is epoxy adhesive composition that combine the benefits of both 1K and 2K technologies in one system which demonstrates a good balance of fast fixation, curing speed, desirable mechanical performance, durability, and good oil adsorption once cured. Said epoxy adhesive composition comprising an epoxy resin, a reactive urethane group- and/or urea group-containing polymer having capped isocyanate, an epoxy curing catalyst, a dicyandiamide, and a hardener.

Abstract: The present invention is a toughened one component epoxy adhesive composition demonstrating improved resistance to humidity. Wherein said one-part structural adhesive comprises: A) a blocked PU-polymer toughener compound; B) an epoxy resin component comprising a solid epoxy resin, a liquid epoxy resin, or mixture thereof; C) a curing agent; D) a urea compound; and E) optionally a filler, wherein the blocked PU-polymer toughener (A) is a reaction product of a reaction mixture comprising of: i) a polyether, ii) a hydroxyl-terminated polybutadiene, iii) a polyisocyanate, iv) a chain extender, and v) a capping group.