Patents by Inventor Andreas M. Cramieri

Andreas M. Cramieri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
    Patent number: 6413774
    Abstract: A method for DNA reassembly after random fragmentation, and its application to mutagenesis of nucleic acid sequences by in vitro or in vivo recombination is described. In particular, a method for the production of nucleic acid fragments or polynucleotides encoding mutant proteins is described. The present invention also relates to a method of repeated cycles of mutagenesis, shuffling and selection which allow for the directed molecular evolution in vitro or in vivo of proteins.
    Type: Grant
    Filed: January 29, 1999
    Date of Patent: July 2, 2002
    Assignee: Maxygen, Inc.
    Inventors: Willem P. C. Stemmer, Andreas M. Cramieri