Patents by Inventor Andrei V. Blokhin

Andrei V. Blokhin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6809176
    Abstract: Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: October 26, 2004
    Assignee: SLIL Biomedical, Corporation
    Inventors: Andrei V. Blokhin, Benjamin Frydman, Laurence J. Marton, Karen M. Neder, Jerry Shunneng Sun
  • Patent number: 6794545
    Abstract: Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to, porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: September 21, 2004
    Assignee: SLIL Biomedical Corporation
    Inventors: Benjamin Frydman, Laurence J. Marton, Venodhar K. Reddy, Aldonia Valasinas, Andrei V. Blokhin, Hirak S. Basu
  • Publication number: 20040152687
    Abstract: Porphyrin-polyamine conjugate compounds are disclosed which have anticancer and antitumor effects. The porphyrin moiety selectively localizes in tumors, while the polyamine moiety serves as a cytotoxic agent. Methods of making and using the porphyrin-polyamine conjugate compounds are also disclosed.
    Type: Application
    Filed: June 24, 2003
    Publication date: August 5, 2004
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Venodhar K. Reddy, Hirak S. Basu, Aparajita Sarkar, Subhra Bhattacharya, Yu Wang, Laurence J. Marton, Andrei V. Blokhin
  • Publication number: 20030195377
    Abstract: Conformationally restricted polyamine compounds useful in treatment of cancer and other diseases marked by abnormal cell proliferation are disclosed. Improved methods of synthesizing such compounds are also disclosed. In one method of the invention, a carbene-bearing or carbene equivalent-bearing compound is reacted with the double bond of an alkene compound to form a cyclopropyl ring as the first step in the synthesis.
    Type: Application
    Filed: December 6, 2002
    Publication date: October 16, 2003
    Applicant: SLIL Biomedical Corporation
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Andrei V. Blokhin, Aparajita Sarkar, Hirak S. Basu, Venodhar K. Reddy, Laurence J. Marton, Yu Wang
  • Publication number: 20030130356
    Abstract: Oligoamine compounds with anti-cancer and anti-proliferative activity are provided, as well as methods for making and using the compounds. The compounds are shown to be active against prostate cancer cell lines and against prostate cancer tumors in mice. The compounds are also useful in treatment of breast cancer and other cancers.
    Type: Application
    Filed: October 16, 2002
    Publication date: July 10, 2003
    Applicant: SLIL Biomedical Corporation
    Inventors: Benjamin Frydman, Aldonia L. Valasinas, Andrei V. Blokhin, Hirak S. Basu, Laurence J. Marton
  • Publication number: 20030013677
    Abstract: Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
    Type: Application
    Filed: April 27, 2000
    Publication date: January 16, 2003
    Inventors: Andrei V. Blokhin, Benjamin Frydman, Laurence J. Marton, Karen M. Neder, Jerry Shunneng Sun
  • Publication number: 20020183512
    Abstract: Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
    Type: Application
    Filed: May 6, 2002
    Publication date: December 5, 2002
    Applicant: SLIL Biomedical Corporation
    Inventors: Andrei V. Blokhin, Benjamin Frydman, Laurence J. Marton, Karen M. Neder, Jerry Shunneng Sun
  • Patent number: 6482943
    Abstract: Novel quinones are provided, as well as compositions comprising these novel quinones. Methods of using the novel quinones in treatment of various indications including cancer are also provided.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: November 19, 2002
    Assignee: SLIL Biomedical Corporation
    Inventors: Andrei V. Blokhin, Benjamin Frydman, Laurence J. Marton, Karen M. Neder, Jerry Shunneng Sun