Patents by Inventor Andrew I. FLYAK

Andrew I. FLYAK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210324051
    Abstract: The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
    Type: Application
    Filed: July 1, 2021
    Publication date: October 21, 2021
    Inventors: James E. CROWE, Jr., Andrew I. FLYAK, Alexander BUKREYEV, Philipp ILINYKH
  • Patent number: 11084869
    Abstract: The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
    Type: Grant
    Filed: October 15, 2019
    Date of Patent: August 10, 2021
    Assignees: VANDERBILT UNIVERSITY, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: James E. Crowe, Jr., Andrew I. Flyak, Alexander Bukreyev, Philipp Ilinykh
  • Patent number: 11054423
    Abstract: The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: July 6, 2021
    Assignees: VANDERBILT UNIVERSITY, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: James E. Crowe, Jr., Andrew I. Flyak, Alexander Bukreyev, Philipp Ilinykh
  • Publication number: 20200200749
    Abstract: The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 25, 2020
    Inventors: James E. CROWE, Jr., Andrew I. FLYAK, Alexander BUKREYEV, Philipp ILINYKH
  • Patent number: 10620204
    Abstract: The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the immunodetection methods described above.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: April 14, 2020
    Assignees: VANDERBILT UNIVERSITY, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: James E. Crowe, Jr., Andrew I. Flyak, Alexander Bukreyev, Philipp Ilinykh
  • Publication number: 20200040066
    Abstract: The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
    Type: Application
    Filed: October 15, 2019
    Publication date: February 6, 2020
    Inventors: James E. CROWE, Jr., Andrew I. FLYAK, Alexander BUKREYEV, Philipp ILINYKH
  • Patent number: 10479825
    Abstract: The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: November 19, 2019
    Assignees: VANDERBILT UNIVERSITY, BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: James E. Crowe, Andrew I. Flyak, Alexander Bukreyev, Philipp Ilinykh
  • Publication number: 20180312574
    Abstract: The present disclosure is directed to antibodies binding to Marburg virus (MARV) glycoprotein (GP) and methods of use therefore.
    Type: Application
    Filed: February 25, 2016
    Publication date: November 1, 2018
    Inventors: James E. CROWE, Andrew I. FLYAK, Alexander BUKREYEV, Philipp ILINYKH
  • Publication number: 20180180614
    Abstract: The present disclosure is directed to antibodies binding to and neutralizing ebolavirus and methods for use thereof. The present disclosure is directed to a method of detecting an ebolavirus infection in a subject comprising (a) contacting a sample from said subject with an antibody or antibody fragment having clone-paired heavy and light chain CDR sequences from Table 2, or an antibody fragment thereof; and (b) detecting ebolavirus glycoprotein in said sample by binding of said antibody or antibody fragment to antigen in said sample. In still further embodiments, the present disclosure concerns immunodetection kits for use with the iminunodetection methods described above.
    Type: Application
    Filed: March 25, 2016
    Publication date: June 28, 2018
    Inventors: James E. CROWE, JR., Andrew I. FLYAK, Alexander BUKREYEV, Philipp ILINYKH