Patents by Inventor Andrew P. Miller

Andrew P. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9689031
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: July 14, 2007
    Date of Patent: June 27, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod W. Provins, Richard B Roth, Jeffrey G. Mandell
  • Patent number: 9617586
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: April 11, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard B. Roth, Jeffrey Mandell
  • Patent number: 9617587
    Abstract: The technology relates in part to methods and compositions for isothermal amplification of nucleic acids.
    Type: Grant
    Filed: April 4, 2016
    Date of Patent: April 11, 2017
    Assignee: NAT DIAGNOSTICS, INC.
    Inventors: Andrew P. Miller, Honghua Zhang
  • Patent number: 9562263
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: February 7, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard Roth, Jeffrey Mandell
  • Patent number: 9562264
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: February 7, 2017
    Assignee: Ionian Technologies, Inc.
    Inventors: Brian K Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard Roth, Jeffrey Mandell
  • Patent number: 9332943
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert can be less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The insert includes a flexible articular surface. Flexible articular surface transfers loading to sensors internal to the insert.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: May 10, 2016
    Assignee: ORTHOSENSOR INC
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Patent number: 9161717
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The internal cavity is isolated from the external environment and can be hermetically sealed. The exterior surfaces of the support structure and the support structure are sterilized.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: October 20, 2015
    Assignee: ORTHOSENSOR INC.
    Inventors: Marc Stein, Andrew P. Miller, Andrew U. Chase, Jason Addink
  • Patent number: 8926530
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The cavity is sterilized through a port. A membrane is between the port and the cavity. A sterilization gas permeates the membrane for sterilizing cavity. The membrane prevents ingress of solids and liquids to the cavity.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: January 6, 2015
    Assignee: OrthoSensor Inc
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20140093883
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Application
    Filed: October 30, 2013
    Publication date: April 3, 2014
    Applicant: Ionian Technologies, Inc.
    Inventors: Brian K. Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard Roth, Jeffrey Mandell
  • Publication number: 20140072978
    Abstract: The invention is in general directed to the rapid exponential amplification of short DNA or RNA sequences at a constant temperature.
    Type: Application
    Filed: October 30, 2013
    Publication date: March 13, 2014
    Applicant: Ionian Technologies, Inc.
    Inventors: Brian K Maples, Rebecca C. Holmberg, Andrew P. Miller, Jarrod Provins, Richard Roth, Jeffrey Mandell
  • Publication number: 20130079672
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert can be less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The insert includes a flexible articular surface. Flexible articular surface transfers loading to sensors internal to the insert.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20130079674
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The internal cavity is isolated from the external environment and can be hermetically sealed. The exterior surfaces of the support structure and the support structure are sterilized.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20130079668
    Abstract: At least one embodiment is directed to an insert sensing device for measuring a parameter of the muscular-skeletal system. The insert sensing device can be temporary or permanent. The insert sensing device is a self-contained encapsulated measurement device. The insert sensing device comprises a support structure having an articular surface for allowing articulation of the muscular-skeletal system and a support structure having a load bearing surface. The structures attach together to form a housing that includes one or more sensors, a power source, electronic circuitry, and communication circuitry. Shims can be attached to the load-bearing surface to adjust the height of insert sensing device. The structures are substantially dimensionally equal to a passive final insert. The sensors are placed between a pad region and a load plate.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink
  • Publication number: 20130079671
    Abstract: At least one embodiment is directed to an insert sensing device for measuring a parameter of the muscular-skeletal system. The insert sensing device can be temporary or permanent. The insert sensing device is a self-contained encapsulated measurement device. The insert sensing device comprises a support structure having an articular surface for allowing articulation of the muscular-skeletal system and a support structure having a load bearing surface. The structures attach together to form a housing that includes one or more sensors, a power source, electronic circuitry, and communication circuitry. Shims can be attached to the load-bearing surface to adjust the height of insert sensing device. The structures are substantially dimensionally equal to a passive final insert. The sensors are placed between a pad region and a load plate.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink
  • Publication number: 20130079884
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load-bearing surface. At least one of the support structures comprises polycarbonate. The polycarbonate allows short-range transmission of measurement data. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The internal cavity is isolated from the external environment and can be hermetically sealed.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20130079670
    Abstract: At least one embodiment is directed to an insert sensing device for measuring a parameter of the muscular-skeletal system. The insert sensing device can be temporary or permanent. The insert sensing device is a self-contained encapsulated measurement device. The insert sensing device comprises a support structure having an articular surface for allowing articulation of the muscular-skeletal system and a support structure having a load bearing surface. The structures attach together to form a housing that includes one or more sensors, a power source, electronic circuitry, and communication circuitry. The electronic circuitry, power source, and communication circuitry are placed in a cavity of the insert sensing device that is unloaded or lightly loaded by the muscular-skeletal system. Shims can be attached to the load-bearing surface to adjust the height of insert sensing device.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink
  • Publication number: 20130079669
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The cavity can be sterilized through a port. A membrane is between the port and the cavity. A sterilization gas permeates the membrane for sterilizing cavity. The membrane reduces the ingress of solids and liquids to the cavity.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20130079673
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The cavity is sterilized through a port. A membrane is between the port and the cavity. A sterilization gas permeates the membrane for sterilizing cavity. The membrane prevents ingress of solids and liquids to the cavity.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: OrthoSensor
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20130079675
    Abstract: At least one embodiment is directed to an insert for measuring a parameter of the muscular-skeletal system. The insert can be temporary or permanent. In one embodiment, the insert is prosthetic component for a single compartment of the knee. The insert comprises a support structure and a support structure respectively having an articular surface and a load bearing surface. The height of the insert is less than 10 millimeters. At least one internal cavity is formed when support structures are coupled together for housing electronic circuitry, sensors, and the power source. The sensors are supported by support structure on pad regions. A planar interconnect couples the sensors to electronic circuitry. The planar interconnect includes a tab that couples to a connector coupled to a printed circuit board.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: ORTHOSENSOR
    Inventors: Marc Stein, Andrew P. Miller, Jason Addink, Andrew U. Chase
  • Publication number: 20100273256
    Abstract: Methods for isolating K+Hnov genes are provided. The K+Hnov nucleic acid compositions find use in identifying homologous or related proteins and the DNA sequences encoding such proteins; in producing compositions that modulate the expression or function of the protein; and in studying associated physiological pathways. In addition, modulation of the gene activity in vivo is used for prophylactic and therapeutic purposes, such as identification of cell type based on expression, and the like.
    Type: Application
    Filed: April 8, 2009
    Publication date: October 28, 2010
    Applicant: ICAGEN, INC.
    Inventors: ANDREW P. MILLER, PING HU, MARK EDWARD CURRAN, MARC RUTTER, JIAN-YING WANG