Patents by Inventor Andrew Tri Van Ho

Andrew Tri Van Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
    Publication number: 20240115583
    Abstract: Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.
    Type: Application
    Filed: May 15, 2023
    Publication date: April 11, 2024
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Adelaida R. Palla, Andrew Tri Van Ho
  • Compositions and methods for preventing or treating muscle conditions
    Patent number: 11738031
    Abstract: Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.
    Type: Grant
    Filed: August 11, 2021
    Date of Patent: August 29, 2023
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Helen M. Blau, Adelaida R. Palla, Andrew Tri Van Ho
  • METHODS OF REJUVENATING AGED TISSUE BY INHIBITING 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE (15-PGDH)
    Publication number: 20220304992
    Abstract: The present disclosure provides compositions and methods based on the identification of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) as a therapeutic target in aging, dystrophic muscle to improve muscle atrophy, increase muscle mass, function and strength. Further provided herein are compositions and methods for the rejuvenation of aged tissue. In particular, 15-PGDH inhibitors, such as SW033291, are used to elevate the levels of prostaglandin E2 (PGE2) in the muscle or tissue.
    Type: Application
    Filed: June 11, 2020
    Publication date: September 29, 2022
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Adelaida Rosa Palla, Andrew Tri Van Ho
  • COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
    Publication number: 20220265677
    Abstract: Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.
    Type: Application
    Filed: August 11, 2021
    Publication date: August 25, 2022
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Adelaida R. Palla, Andrew Tri Van Ho
  • Compositions and Methods for Muscle Regeneration Using Prostaglandin E2
    Publication number: 20200147103
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Application
    Filed: August 22, 2019
    Publication date: May 14, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla
  • Compositions and methods for muscle regeneration using prostaglandin E2
    Patent number: 10449205
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: October 22, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla
  • COMPOSITIONS AND METHODS FOR PREVENTING OR TREATING MUSCLE CONDITIONS
    Publication number: 20190167695
    Abstract: Provided herein are compositions for preventing or treating muscle conditions such as muscle damage, injury, or atrophy. In some embodiments, the compositions comprise a prostaglandin E2 (PGE2) compound and a myotoxin. In some embodiments, the muscle damage, injury, or atrophy is the result of a nerve injury, a surgical procedure, or a traumatic injury. Methods of promoting muscle regeneration and methods of increasing muscle mass are also provided herein.
    Type: Application
    Filed: October 1, 2018
    Publication date: June 6, 2019
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Adelaida R. Palla, Andrew Tri Van Ho
  • Compositions and Methods for Muscle Regeneration Using Prostaglandin E2
    Publication number: 20180200264
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Application
    Filed: March 9, 2018
    Publication date: July 19, 2018
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla
  • Compositions and Methods for Muscle Regeneration Using Prostaglandin E2
    Publication number: 20180177799
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Application
    Filed: February 7, 2018
    Publication date: June 28, 2018
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla
  • Compositions and methods for muscle regeneration using prostaglandin E2
    Patent number: 9918994
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Grant
    Filed: April 26, 2017
    Date of Patent: March 20, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla
  • Compositions and Methods for Muscle Regeneration Using Prostaglandin E2
    Publication number: 20170252354
    Abstract: Provided herein are compositions, methods, and kits for proliferating muscle cells by exposing the muscle cells to a prostaglandin E2 (PGE2) compound or compound that activates PGE2 signaling. Also provided are methods for regenerating muscle in a subject suffering from muscular atrophy, dystrophy, and/or injury by administering a PGE2 compound alone or in combination with isolated muscle cells. The PGE2 compound in combination with the isolated muscle cells can be administered prophylactically to prevent a muscle disease or condition.
    Type: Application
    Filed: April 26, 2017
    Publication date: September 7, 2017
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Helen M. Blau, Andrew Tri Van Ho, Adelaida R. Palla