Abstract: The present application relates to plasma cells and plasma cell precursors that express a macromolecule, such as a protein, protein mimetic or a peptide and compositions comprising these plasma cells or plasma cell precursors. The application further relates to methods of using and making the plasma cells and plasma cell precursors that express the macromolecule. Methods of treatment comprising administering the plasma cells or plasma cell precursors are also contemplated.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A system and method for utilizing circuit switched and packet switched resources are disclosed. A voice communication system configured for routing calls from multiple users to circuit switched or packet switched resources generally comprises a hub in communication with at least one circuit switched channel, at least one packet switched channel, and a plurality of user devices. The system further includes a controller operable to select the circuit switched channel or the packet switched channel for connection with one of the user devices when a call is placed to or from the user device and a routing device operable to route the call from the user device to the selected channel.

Abstract: Selectively oxidized vertical cavity lasers emitting at about 1290 nm using InGaAsN quantum wells that operate continuous wave below, at and above room temperature are reported. The lasers employ a semi-insulating GaAs substrate for reduced capacitance, high quality, low resistivity AlGaAs DBR mirror structures, and a strained active region based on InGaAsN. In addition, the design of the VCSEL reduces free carrier absorption of 1.3 ?m light in the p-type materials by placing relatively higher p-type dopant concentrations near standing wave nulls.

Abstract: A VCSEL (vertical cavity surface emitting laser) is formed on the top surface of the substrate having an opposed bottom surface. In one exemplary embodiment, the opposed bottom surface is polished and coated with an anti-reflective coating. A photodetector is disposed beneath the bottom surface and is capable of detecting light emitted by the VCSEL. In another embodiment, an angle selective filter is disposed between the photodetector and the unpolished and uncoated bottom surface. The apparatus urges light emitted by the VCSEL to be detected by the photodetector and limits light from other sources from reaching the photodetector. A method for monitoring the optical output of a VCSEL includes providing one of the exemplary apparatuses, causing the VCSEL to emit light that is detected by the photodetector, and adjusting the optical output of the VCSEL based on the amount of light detected by the photodetector.

Abstract: Selectively oxidized vertical cavity lasers emitting at about 1290 nm using InGaAsN quantum wells that operate continuous wave below, at and above room temperature are reported. The lasers employ a semi-insulating GaAs substrate for reduced capacitance, high quality, low resistivity AlGaAs DBR mirror structures, and a strained active region based on InGaAsN. In addition, the design of the VCSEL reduces free carrier absorption of 1.3 ?m light in the p-type materials by placing relatively higher p-type dopant concentrations near standing wave nulls.

Abstract: A system and method for utilizing circuit switched and packet switched resources are disclosed. A voice communication system configured for routing calls from multiple users to circuit switched or packet switched resources generally comprises a hub in communication with at least one circuit switched channel, at least one packet switched channel, and a plurality of user devices. The system further includes a controller operable to select the circuit switched channel or the packet switched channel for connection with one of the user devices when a call is placed to or from the user device and a routing device operable to route the call from the user device to the selected channel.

Abstract: A VCSEL (vertical cavity surface emitting laser) is formed on the top surface of the substrate having an opposed bottom surface. In one exemplary embodiment, the opposed bottom surface is polished and coated with an anti-reflective coating. A photodetector is disposed beneath the bottom surface and is capable of detecting light emitted by the VCSEL. In another embodiment, an angle selective filter is disposed between the photodetector and the unpolished and uncoated bottom surface. The apparatus urges light emitted by the VCSEL to be detected by the photodetector and limits light from other sources from reaching the photodetector. A method for monitoring the optical output of a VCSEL includes providing one of the exemplary apparatuses, causing the VCSEL to emit light that is detected by the photodetector, and adjusting the optical output of the VCSEL based on the amount of light detected by the photodetector.

Abstract: Selectively oxidized vertical cavity lasers emitting at about 1290 nm using InGaAsN quantum wells that operate continuous wave below, at and above room temperature are reported. The lasers employ a semi-insulating GaAs substrate for reduced capacitance, high quality, low resistivity AlGaAs DBR mirror structures, and a strained active region based on InGaAsN. In addition, the design of the VCSEL reduces free carrier absorption of 1.3 &mgr;m light in the p-type materials by placing relatively higher p-type dopant concentrations near standing wave nulls.

Abstract: Selectively oxidized vertical cavity lasers emitting at about 1290 nm using InGaAsN quantum wells that operate continuous wave below, at and above room temperature are reported. The lasers employ a semi-insulating GaAs substrate for reduced capacitance, high quality, low resistivity AlGaAs DBR mirror structures, and a strained active region based on InGaAsN. In addition, the design of the VCSEL reduces free carrier absorption of 1.3 &mgr;m light in the p-type materials by placing relatively higher p-type dopant concentrations near standing wave nulls.

Abstract: The present invention 10 discloses an apparatus and method for a storm shelter which can be used aboveground and belowground, and, may be skin supported. The present invention discloses that its top 11, front 13 and rear 15 surfaces can be made from a single, curved piece of material 12, and, that its sides 14 are made from two straight pieces of material all of which pieces are mounted onto parallel curved fine members 18 which are mounted onto a base frame 16 which is anchored to a foundation 34. The storm shelter of the present invention can be manufactured and pre-assembled in an embodiment having a single piece 12, top 11, front 13 and rear 15 construction or in an embodiment having a multiple piece 46 and 48, top 11, front 13 and rear 15 construction designed for on-site construction in the form of a kit or pieces which can be assembled on-site.

Abstract: In a chair having a frame, a fixed seat, and a pivotal back, the frame includes two bridge-supporting legs extending between an upper position and a lower position behind and below the upper position. A transverse bridge fitting removably into openings in the bridge-supporting legs bridges the bridge-supporting legs in at least two orientations. The bridge limits pivotal movement of the back, when pivoted downwardly and backwardly, to at least two reclined positions. In one contemplated embodiment wherein the transverse bridge comprises a beam fitting removably and nonrotatably into the openings and bridging the bridge-supporting legs in two such orientations, a spacer extending along and mounted fixedly to the transverse beam is interposed between the transverse beam and the back in one such orientation but not in the other orientation.

Abstract: A method and apparatus for preprocessing digital voice data enroute to or from a Telephone's CODEC. The apparatus supports a CODEC directly connected to an internal bus and using a separate CODEC clock and sync signal to control transfers between a telephony link/internal bus interface and the CODEC. According to an embodiment of the present invention, an auxiliary processing device (connected to the internal bus side of the phone) is provided with means to process the digital voice information before sending it uplink or to the CODEC. This is accomplished without changing the position of the incoming voice field.

Abstract: A method and apparatus for transferring data between telephony communications lines having different frame transmission rates. A downlink data frame according to a first protocol (e.g. a ROLMlink frame) is transmitted, at a first data rate, from a private branch exchange (PBX) to a telephone's network interface. One or more fields of data from this frame are collected in shift register which is internal to the interface. After collection, the data is injected into a downlink data frame of the telephone's internal protocol (e.g. a GCI frame), which is being transmitted on the telephone side of the interface at a second data rate (different from the first data rate). Simultaneously with the injecting, one or more fields of data from an uplink data frame of the telephone's internal protocol are shifted into the same register for later injection into an uplink data frame, of the external protocol, destined for the PBX.

Abstract: Hydrostatic energy is converted to kinetic energy preferably for generating electricity by driving a fluid actuated motor connected to an electrical generator. Pumps are arranged in parallel for driving the motor, and are in turn actuated by engines driven themselves by a liquid contained in a reservoir in which the engines are disposed. The liquid in the reservoir is transferred to and from and also between the engines for actuating same.

Abstract: A highly aerodynamically stable kite having a flexible statically indeterminate face which during flight forms a curvilinear airfoil that is maintained in the center and top edges by rigid linear stiffeners removably retained in a novel nosepiece. The nosepiece is a rigid three dimensional structure formed by folding a thin flat pattern. A novel tail member aids kite stability by providing plural aerodynamically rotatable elements spacedly depending beneath the kite upon a common flexible line.