Patents by Inventor Angel Garcia-Diaz

Angel Garcia-Diaz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for immunotherapy-based treatment and assessment of cancer
    Patent number: 10711312
    Abstract: Disclosed herein are methods of treating or assessing cancer in a subject wherein it has been determined whether the cancer comprises a loss of function mutation or disruption in an immune pathway. The loss of function mutation or disruption can be in JAK1 or JAK2. The loss of function mutation or disruption can be in B2M. The methods can include administering an immune checkpoint therapy such as anti-PD1 or anti-PDL1. The methods can include administering an alternative therapy to an immune checkpoint therapy. In some aspects, the method includes determining whether the cancer comprises a loss of function mutation or disruption in an immune pathway.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: July 14, 2020
    Assignee: The Regents of the University of California
    Inventors: Antoni Ribas, Jesse Zaretsky, Daniel Shin, Angel Garcia-Diaz, Blanca Homet Moreno
  • METHODS FOR IMMUNOTHERAPY-BASED TREATMENT AND ASSESSMENT OF CANCER
    Publication number: 20180051347
    Abstract: Disclosed herein are methods of treating or assessing cancer in a subject wherein it has been determined whether the cancer comprises a loss of function mutation or disruption in an immune pathway. The loss of function mutation or disruption can be in JAK1 or JAK2. The loss of function mutation or disruption can be in B2M. The methods can include administering an immune checkpoint therapy such as anti-PD1 or anti-PDL1. The methods can include administering an alternative therapy to an immune checkpoint therapy. In some aspects, the method includes determining whether the cancer comprises a loss of function mutation or disruption in an immune pathway.
    Type: Application
    Filed: July 12, 2017
    Publication date: February 22, 2018
    Inventors: Antoni Ribas, Jesse Zaretsky, Daniel Shin, Angel Garcia-Diaz, Blanca Homet Moreno