Patents by Inventor Anita Melikian

Anita Melikian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted quinolones and methods of use
    Patent number: 7557213
    Abstract: Substituted quinolone compounds and compositions are provided along with methods for the use of those compounds in the treatment of diseases and disorders such as cancer.
    Type: Grant
    Filed: November 13, 2006
    Date of Patent: July 7, 2009
    Assignee: ChemoCentryx, Inc.
    Inventors: Anita Melikian, John Jessen Wright, Antoni Krasinski, Cheng Hu, Aaron Novack
  • N-(2-(HETARYL)ARYL) ARYLSULFONAMIDES AND N-(2-(HETARYL) HETARYL ARYLSULFONAMIDES
    Publication number: 20090005410
    Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
    Type: Application
    Filed: June 17, 2008
    Publication date: January 1, 2009
    Applicant: CHEMOCENTRYX, INC.
    Inventors: Trevor T. Charvat, Cheng Hu, Anita Melikian, Aaron Novack, Andrew M.K. Pennell, Edward J. Sullivan, William D. Thomas, Solomon Ungashe, Penglie Zhang, Jay Powers, Sreenivas Punna
  • Substituted arylamides
    Patent number: 7417062
    Abstract: Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer.
    Type: Grant
    Filed: August 11, 2005
    Date of Patent: August 26, 2008
    Assignee: ChemoCentryx, Inc.
    Inventors: Anita Melikian, John J. Kim Wright
  • TRIAZOLYL PYRIDYL BENZENESULFONAMIDES
    Publication number: 20080039504
    Abstract: Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists.
    Type: Application
    Filed: July 10, 2007
    Publication date: February 14, 2008
    Inventors: Trevor Charvat, Cheng Hu, Jeff Jin, Yandong Li, Anita Melikian, Andrew Pennell, Sreenivas Punna, Solomon Ungashe, Yibin Zeng
  • TRIAZOLYL PHENYL BENZENESULFONAMIDES
    Publication number: 20080039465
    Abstract: Compounds are provided that act as potent antagonists of the CCR2 or CCR9 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2 and CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, CCR9-mediated diseases, as controls in assays for the identification of CCR2 antagonists and as controls in assays for the identification of CCR9 antagonists.
    Type: Application
    Filed: July 10, 2007
    Publication date: February 14, 2008
    Inventors: Trevor Charvat, Cheng Hu, Anita Melikian, Aaron Novack, Andrew Pennell, Sreenivas Punna, Edward Sullivan, Xuefei Tan, William Thomas, Solomon Ungashe, Yibin Zeng
  • Substituted quinolones and methods of use
    Publication number: 20070167443
    Abstract: Substituted quinolone compounds and compositions are provided along with methods for the use of those compounds in the treatment of diseases and disorders such as cancer.
    Type: Application
    Filed: November 13, 2006
    Publication date: July 19, 2007
    Applicant: ChemoCentryx, Inc.
    Inventors: Anita Melikian, John Wright, Antoni Krasinski, Cheng Hu, Aaron Novack
  • CCR2 inhibitors and methods of use thereof
    Publication number: 20070021466
    Abstract: Compounds are provided that act as potent antagonists of the CCR2 receptor. These compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CCR2 antagonists.
    Type: Application
    Filed: July 13, 2006
    Publication date: January 25, 2007
    Inventors: Solomon Ungashe, John Wright, Andrew Pennell, Zheng Wei, Anita Melikian
  • Substituted N-cinnamyl benzamides
    Publication number: 20070021484
    Abstract: Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer.
    Type: Application
    Filed: June 28, 2006
    Publication date: January 25, 2007
    Applicant: ChemoCentryx, Inc.
    Inventors: Anita Melikian, John J. Wright, Antoni Krasinski
  • Aryl sulfonamides
    Publication number: 20060111351
    Abstract: Compounds are provided that act as potent antagonists of the CCR9 receptor, and which have been further confirmed in animal testing for inflammation, one of the hallmark disease states for CCR9. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR9-mediated diseases, and as controls in assays for the identification of CCR9 antagonists.
    Type: Application
    Filed: October 20, 2005
    Publication date: May 25, 2006
    Inventors: Solomon Ungashe, John Wright, Andrew Pennell, Zheng Wei, Anita Melikian
  • Substituted arylamides
    Publication number: 20060074071
    Abstract: Substituted benzamide compounds are provided along with methods for the use of those compounds for treating cancer.
    Type: Application
    Filed: August 11, 2005
    Publication date: April 6, 2006
    Applicant: ChemoCentryx, Inc.
    Inventors: Anita Melikian, John J. Wright
  • Inhibitors of human tumor-expressed CCXCKR2
    Publication number: 20040171655
    Abstract: Pharmaceutical compositions containing organic compounds or salts thereof that serve as modulators for the SDF-1 or I-TAC chemokines are disclosed. The compounds and compositions are useful in the treatment of cancer, especially in the inhibition of cancer proliferation, growth, and metastasis. Methods of interfering with SDF-1 and/or I-TAC binding to the CCXCKR2 receptor and treating cancer using the compounds and pharmaceutical compositions of the present invention are also disclosed.
    Type: Application
    Filed: December 22, 2003
    Publication date: September 2, 2004
    Inventors: Anita Melikian, Jennifer Burns, Brian E. McMaster, Thomas Schall, J.J. Wright
  • Aryl-indane compounds
    Publication number: 20020128231
    Abstract: A new family of compounds, particularly aryl-indane compounds, is disclosed. The compounds may be used as inhibitors of P-glycoprotein-mediated transport. Use of the compounds to enhance bioavailability and to modulate multi-drug resistance to chemotherapeutic agents is disclosed.
    Type: Application
    Filed: October 11, 2001
    Publication date: September 12, 2002
    Inventor: Anita Melikian-Badalian
  • Antimicrobial agents uses and compositions related thereto
    Patent number: 6207679
    Abstract: The present invention provides methods and pharmaceutical preparations that inhibit the growth of bacterial microorganisms. Additionally, the present invention provides methods and pharmaceutical preparations that kill bacterial microorganisms.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: March 27, 2001
    Assignee: Sepracor, Inc.
    Inventors: Gregory D. Cuny, James R. Hauske, Donald L. Heefner, Michael Z. Hoemann, Gnanasambandam Kumaravel, Anita Melikian-Badalian, Richard F. Rossi
  • Quinoline-indole antimicrobial agents, uses and compositions related thereto
    Patent number: 6172084
    Abstract: The present invention provides methods and pharmaceutical preparations that inhibit the growth of bacterial microorganisms. Additionally, the present invention provides methods and pharmaceutical preparations that kill bacterial microorganisms.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: January 9, 2001
    Assignee: Sepracor, Inc.
    Inventors: Gregory D. Cuny, James R. Hauske, Donald L. Heefner, Michael Z. Hoemann, Gnanasambandam Kumaravel, Anita Melikian-Badalian, Richard F. Rossi
  • Quinoline-indole antimicrobial agents, uses and compositions related thereto
    Patent number: 6103905
    Abstract: The present invention provides methods and pharmaceutical preparations that inhibit the growth of bacteria microorganisms. Additionally, the present invention provides methods and pharmaceutical preparations that kill bacterial microorganisms.
    Type: Grant
    Filed: December 11, 1998
    Date of Patent: August 15, 2000
    Assignee: Sepracor, Inc.
    Inventors: Gregory D. Cuny, James R. Hauske, Donald L. Heefner, Michael Z. Hoemann, Gnanasambandam Kumaravel, Anita Melikian-Badalian, Richard F. Rossi, Roger L. Xie
  • Process and intermediates for the preparation of excitatory amino acid receptor antagonists
    Patent number: 5670684
    Abstract: The present invention provides novel intermediates which are useful for the preparation of excitatory amino acid receptor antagonists. Further provided is a process to enatioselectively prepare hydroisoquinoline compounds with central nervous system activity.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: September 23, 1997
    Assignee: Eli Lilly and Company
    Inventors: Anita Melikian-Badalian, Paul L. Ornstein
  • Process and intermediates for the preparation of excitatory amino acid receptor antagonists
    Patent number: 5576435
    Abstract: The present invention provides novel intermediates which are useful for the preparation of excitatory amino acid receptor antagonists. Further provided is a process to enatioselectively prepare hydroisoquinoline compounds with central nervous system activity.
    Type: Grant
    Filed: May 19, 1995
    Date of Patent: November 19, 1996
    Assignee: Eli Lilly and Company
    Inventors: Anita Melikian-Badalian, Paul L. Ornstein
  • Process and intermediates for the preparation of excitatory amino acid receptor antagonists
    Patent number: 5470978
    Abstract: The present invention provides novel intermediates which are useful for the preparation of excitatory amino acid receptor antagonists. Further provided is a process to enatioselectively prepare hydroisoquinoline compounds with central nervous system activity.
    Type: Grant
    Filed: November 18, 1992
    Date of Patent: November 28, 1995
    Assignee: Eli Lilly and Company
    Inventors: Anita Melikian-Badalian, Paul L. Ornstein