Patents by Inventor Ann Lacombe

Ann Lacombe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-idiotypic antibodies against anti-KLK2 antibodies
    Patent number: 12162951
    Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: December 10, 2024
    Assignee: Janssen Biotech, Inc.
    Inventors: Zemeda Ainekulu, Qiang Chen, Ellen Chi, Wilson Edwards, Matt Husovsky, Ann Lacombe, Quynh Nguyen, Paul H. Kim, H. Mimi Zhou, John T. Lee
  • Anti-idiotypic antibodies against anti-GPRC5D antibodies
    Patent number: 12030937
    Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a GP5B83 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include GP5B83.
    Type: Grant
    Filed: July 15, 2021
    Date of Patent: July 9, 2024
    Assignee: Janssen Biotech, Inc.
    Inventors: Ellen Chi, Wilson Edwards, Matt Husovsky, Ann Lacombe, Christian Martinez, H. Mimi Zhou, John T. Lee
  • MOLECULES WITH ENGINEERED ANTIBODY CONSTANT REGION VARIANTS
    Publication number: 20240218083
    Abstract: A binding molecule comprising (i) a first polypeptide comprising a heavy chain variable region (VH) and a region derived from the first constant region of an antibody heavy chain (CH1), and (ii) a second polypeptide comprising a light chain variable region (VL) and a region derived from the constant region of an antibody light chain (CL), wherein the region derived from the CH1 region and/or the region derived from the CL region comprises one or more antigen binding loop(s).
    Type: Application
    Filed: April 18, 2022
    Publication date: July 4, 2024
    Inventors: Sanjaya SINGH, Ellen CHI, Martin CASE, Hong Mimi ZHOU, Linus HYUN, Jennifer FURMAN, Ann LACOMBE
  • Antibodies that Specifically Bind PD-1 and Methods of Use
    Publication number: 20230340155
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Application
    Filed: June 8, 2023
    Publication date: October 26, 2023
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Antibodies that specifically bind PD-1 and methods of use
    Patent number: 11746161
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: September 5, 2023
    Assignee: Janssen Biotech, Inc.
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • ANTI-IDIOTYPIC ANTIBODIES AGAINST ANTI-GPRC5D ANTIBODIES
    Publication number: 20220064284
    Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a GP5B83 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include GP5B83.
    Type: Application
    Filed: July 15, 2021
    Publication date: March 3, 2022
    Inventors: Ellen CHI, Wilson EDWARDS, Matt HUSOVSKY, Ann LACOMBE, Christian MARTINEZ, H. Mimi ZHOU, John T. LEE
  • ANTI-IDIOTYPIC ANTIBODIES AGAINST ANTI-KLK2 ANTIBODIES
    Publication number: 20220064334
    Abstract: In certain aspects, the disclosure relates to anti-idiotype antibodies and antigen-binding portions thereof that specifically bind a KL2B413 containing protein, e.g., an antibody or antigen-binding portions thereof. In some aspects, the anti-idiotype antibodies and antigen-binding portions of the present disclosure can be used in methods to detect and quantify cells expressing chimeric antigen receptors that include KL2B413.
    Type: Application
    Filed: July 15, 2021
    Publication date: March 3, 2022
    Inventors: Zemeda AINEKULU, Qiang CHEN, Ellen CHI, Wilson EDWARDS, Matt HUSOVSKY, Ann LACOMBE, Quynh NGUYEN, Paul H. KIM, H. Mimi ZHOU, John T. LEE
  • Antibodies that specifically bind PD-1 and methods of use
    Patent number: 10995149
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: May 4, 2021
    Assignee: Janssen Biotech, Inc.
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Antibodies that Specifically Bind PD-1 and Methods of Use
    Publication number: 20210102000
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Application
    Filed: December 17, 2020
    Publication date: April 8, 2021
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yevgeniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson
  • Antibodies that Specifically Bind PD-1 and Methods of Use
    Publication number: 20180355061
    Abstract: Antibodies that specifically bind PD-1 or antigen binding fragments thereof, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of an inflammatory or immune disorder.
    Type: Application
    Filed: June 4, 2018
    Publication date: December 13, 2018
    Inventors: Qiang Chen, Suzanne Cole, Karen Duffy, Yanxia Guo, Debra Gardner, Damon Hamel, Shannon Hitchcock, Ann Lacombe, Jinquan Luo, Ravi Malaviya, Yavegniya Orlovsky, Pejman Soroosh, Melissa Swiecki, Deepti Wilkinson