Patents by Inventor Anna-Barbara Moscicki

Anna-Barbara Moscicki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof
    Patent number: 8252893
    Abstract: The present invention is directed to the examination of the pattern of immunodominant CD8 T cell epitopes in the E6 and E7 protein of Human Papillomavirus (HPV) and its further characterization in terms of its amino acid sequence and HLA restriction. These epitopes are identified based on their ability to induce strong CD8 T cell response and therefore, are important as sources of antigens for dendritic cell immunotherapy to treat cervical cancer. The present invention contemplates identifying a number of similar epitopes restricted by a wide variety of HLA types so that they can be used in concert to develop a preventative vaccine, which can be used for general population.
    Type: Grant
    Filed: January 31, 2006
    Date of Patent: August 28, 2012
    Assignee: Board of Trustees of the University of Arkansas
    Inventors: Kevin H. Kim, Mayumi Nakagawa, Anna-Barbara Moscicki
  • CD8 T cell epitopes in HPV 16 E6 and E7 proteins and uses thereof
    Publication number: 20060182763
    Abstract: The present invention is directed to the examination of the pattern of immunodominant CD8 T cell epitopes in the E6 and E7 protein of Human Papillomavirus (HPV) and its further characterization in terms of its amino acid sequence and HLA restriction. These epitopes are identified based on their ability to induce strong CD8 T cell response and therefore, are important as sources of antigens for dendritic cell immunotherapy to treat cervical cancer. The present invention contemplates identifying a number of similar epitopes restricted by a wide variety of HLA types so that they can be used in concert to develop a preventative vaccine, which can be used for general population.
    Type: Application
    Filed: January 31, 2006
    Publication date: August 17, 2006
    Inventors: Kevin Kim, Mayumi Nakagawa, Anna-Barbara Moscicki