Patents by Inventor Annalisa Airoldi

Annalisa Airoldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8648078
    Abstract: The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
    Type: Grant
    Filed: July 22, 2010
    Date of Patent: February 11, 2014
    Assignee: Nerviano Medical Sciences S.R.L.
    Inventors: Massimo Zampieri, Italo Beria, Annalisa Airoldi, Ilaria Candiani, Riccardo Frigerio
  • Patent number: 8586598
    Abstract: The present invention relates to novel crystalline form(s) of water-soluble salts and of free base of a cdk inhibitor. Such crystal salts are for example fumarate, L-malate, maleate, succinate, adipate, malonate, glycolate, phosphate, mesylate, L-lactate, hydrochloride, di-hydrochloride, tri-hydrochloride. Hydrates and polymorphs of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: November 19, 2013
    Assignee: Nerviano Medical Sciences S.R.L.
    Inventors: Massimo Zampieri, Annalisa Airoldi, Maria Gioia Fornaretto, Maria Gabriella Brasca
  • Publication number: 20120157468
    Abstract: The present invention relates to novel crystalline, water-soluble salts of a plk inhibitor. Such crystal salts are for example L-tartrate, succinate, phosphate, mesylate, maleate, L-malate, hydrochloride, fumarate (half mole of counterion), fumarate, citrate (half mole of counterion), benzenesulfonate and L-aspartate (half mole of counterion). New crystal forms of the base as well as solvates and hydrates of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
    Type: Application
    Filed: July 22, 2010
    Publication date: June 21, 2012
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Massimo Zampieri, Italo Beria, Annalisa Airoldi, Ilaria Candiani, Riccardo Frigerio
  • Publication number: 20120041007
    Abstract: The present invention relates to novel crystalline form(s) of water-soluble salts and of free base of a cdk inhibitor. Such crystal salts are for example fumarate, L-malate, maleate, succinate, adipate, malonate, glycolate, phosphate, mesylate, L-lactate, hydrochloride, di-hydrochloride, tri-hydrochloride. Hydrates and polymorphs of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
    Type: Application
    Filed: April 23, 2010
    Publication date: February 16, 2012
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Massimo Zampieri, Annalisa Airoldi, Maria Gioia Fornaretto, Maria Gabriella Brasca
  • Publication number: 20090291953
    Abstract: The present invention relates to novel crystalline, water-soluable salts of the 2S,3S enantiomer of reboxetine, which are the fumarate and succinate salts thereof, to a process for their preparation, to their utility in therapy and to pharmaceutical compositions containing them.
    Type: Application
    Filed: May 21, 2009
    Publication date: November 26, 2009
    Inventors: Annalisa Airoldi, Alessando Martini, Massimo Zampieri
  • Publication number: 20070010517
    Abstract: The present invention relates to novel crystalline, water-soluble salts of the 2S,3S enantiomer of reboxetine, which are the fumarate and succinate salts thereof, to a process for their preparation, to their utility in therapy and to pharmaceutical corn-positions containing them.
    Type: Application
    Filed: June 4, 2003
    Publication date: January 11, 2007
    Inventors: Annalisa Airoldi, Alessandro Martini, Massimo Zampieri