Patents by Inventor Anne Dekeyne
Anne Dekeyne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8247441Abstract: The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.Type: GrantFiled: July 20, 2010Date of Patent: August 21, 2012Assignee: Les Laboratoires ServierInventors: Guillaume De Nanteuil, Bernard Cimetiere, Anne Dekeyne, Mark Millan
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Publication number: 20110021490Abstract: The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.Type: ApplicationFiled: July 20, 2010Publication date: January 27, 2011Applicant: LES LABORATOIRES SERVIERInventors: Guillaume De Nanteuil, Bernard Cimetiere, Anne Dekeyne, Mark Millan
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Patent number: 7026357Abstract: Compound of formula (I): and medicinal products containing the same are useful as dual ?2/5-HT2c antagonist receptors.Type: GrantFiled: June 7, 2004Date of Patent: April 11, 2006Assignee: Les Laboratoires ServierInventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Publication number: 20040224993Abstract: Compound of formula (I): 1Type: ApplicationFiled: June 7, 2004Publication date: November 11, 2004Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Patent number: 6784183Abstract: Compounds of formula (I): and medicinal products containing the same which are useful as dual &agr;2/5-HT2c antagonists.Type: GrantFiled: June 29, 2001Date of Patent: August 31, 2004Assignee: Les Laboratoires ServierInventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Patent number: 6747032Abstract: Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, alkoxy, polyhaloalkyl, hydroxy, cyano, nitro and amino, or R1 with R2, R2 with R3, or R3 with R4, together with the carbon atoms carrying them, form an optionally substituted benzene ring or an optionally substituted heteroaromatic ring, X represents an oxygen atom or a methylene group, A represents an alkylene chain, represents an optionally substituted, unsaturated, nitrogen-containing heterocycle and R5 represents an alkyl group, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid, a medicinal products containing the same are useful as a double &agr;2/5-HT2c antagonist.Type: GrantFiled: April 18, 2002Date of Patent: June 8, 2004Assignee: Les Laboratoires ServierInventors: Gilbert Lavielle, Thierry Dubuffet, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Publication number: 20030087916Abstract: Compound of formula (I): 1Type: ApplicationFiled: April 18, 2002Publication date: May 8, 2003Inventors: Gilbert Lavielle, Thierry Dubuffet, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Patent number: 6492366Abstract: A compound selected from those of formula (I): wherein: R1 and R2 each independently represent hydrogen or, alkyl, T1 and T2 each independently represent alkylene, G represents a heterocyclic group selected of formula (&agr;): wherein: W1 to W5 and X1 to X4 are so defined in the description. Medicinal products containing the same are useful as serotonin-reuptake inhibitors.Type: GrantFiled: October 11, 2000Date of Patent: December 10, 2002Assignee: Les Laboratoires ServierInventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Didier Cussac, Anne Dekeyne
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Patent number: 6486171Abstract: A compound selected from those of formula (I): wherein: W represents optionally substituted naphthyl, or a group of formula Y (wherein) as defined in the description, n represents an integer from 1 to 6 inclusive, Z represents a single bond, oxygen, or optionally substituted nitrogen, A and Q each represent CH or nitrogen, it being understood that A or Q must be N and the other CH, M, together with a carbon of the phenyl to which it is bonded, represents thienyl, furyl, pyrrolyl, or oxopyrrolyl, its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same, which are useful in the treatment of some CNS disorders.Type: GrantFiled: March 25, 2002Date of Patent: November 26, 2002Assignee: Les Laboratoires ServierInventors: Jean-Louis Peglion, Aimée Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
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Publication number: 20020161228Abstract: A compound selected from those of formula (I): 1Type: ApplicationFiled: March 25, 2002Publication date: October 31, 2002Applicant: ADIR ET COMPAGNIEInventors: Jean Louis Peglion, Aimee Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
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Patent number: 6399616Abstract: A compound selected from those of formula (I): wherein: W represents optionally substituted naphthyl, n represents an integer from 2 to 3 inclusive, Z represents a single bond, A represents nitrogen, Q represents nitrogen, M, together with the carbon of pyridyl to which it is bonded, represents thieno, furo, pyrrolo or oxopyrrolo, Its optical isomers and pharmaceutically-acceptable acid or base additional salts thereof, and Medicinal products containing the same which are useful in the treatment of CNS disorders. It being understood that “aryl” is phenyl, naphthyl, dihydronaphthyl, or tetrahydronaphthyl.Type: GrantFiled: August 18, 2000Date of Patent: June 4, 2002Assignee: Les Laboratoires ServierInventors: Jean-Louis Peglion, Aimée Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
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Publication number: 20020025965Abstract: 1Type: ApplicationFiled: June 29, 2001Publication date: February 28, 2002Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
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Patent number: 6350757Abstract: A compound selected from those of formula (I): wherein: represents single or double bond, R1 represents hydrogen, alkyl, —R6-aryl, —R6-cycloalkyl, —R6-heterocycle, —CO2R7—, —COR8, or —CONHR8, wherein R6, R7, and R8 are as defined in the description, R2 represents cyano, mono- or di-alkylaminoalkylaminocarbonyl, —CO2R8, —CONHR8, —NR8R9, —NHCO2R7, or —COR8 wherein R7, R8, and R9 are as defined in the description, R3 and R4 together form (C3-C10)cycloalkyl, R5 represents hydrogen, alkyl, or arylalkyl, Ra, Rb, Rc, Rd, which may be identical or different, represent a group as defined in the description, its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of CNS disorders.Type: GrantFiled: July 21, 2000Date of Patent: February 26, 2002Assignee: Les Laboratoires ServierInventors: Solo Goldstein, Guillaume Poissonnet, Jean-Gilles Parmentier, Jean-Daniel Brion, Mark Millan, Anne Dekeyne, Jean Boutin
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Patent number: 6153640Abstract: A compound of formula (I): ##STR1## wherein: R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, represent a group as defined in the description,R.sub.4 represents hydrogen, alky, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocycloalkyl, heterocycloalkylalkyl, heteroaryl, or heteroarylalkyl,R.sub.5 represents aryl, or heteroaryl, each optionally substituted,n is an integer from 1 to 3 inclusive,their isomers and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same are usefull in the treatment of disease like depression, panic attacks, obsessive-compulsive disorders, phobias, impulsive disorders, drug abuse or anxiety.Type: GrantFiled: March 23, 2000Date of Patent: November 28, 2000Assignee: Adir et CompagnieInventors: Jean-Louis Peglion, Bertrand Goument, Aimee Dessinges, Mark Millan, Jean-Michel Rivet, Anne Dekeyne
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Patent number: 6060487Abstract: A compound of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, X--Y, A, Z and Z' are as defined in the description, in the form of the cis or trans isomers each in racemic or optically active form, and acid addition salts thereof, and medicinal products containing the same are useful in the treatment of diseases of the central nervous system or of manifestations of pain.Type: GrantFiled: March 22, 1999Date of Patent: May 9, 2000Assignee: Adir et CompagnieInventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Anne Dekeyne
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Patent number: 5958927Abstract: A compound of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, X-Y, A, Z and Z' are as defined in the description, in the form of the cis or trans isomers each in racemic or optically active form, and acid addition salts thereof, and medicinal products containing the same are useful in the treatment of diseases of the central nervous system or of manifestations of pain.Type: GrantFiled: October 2, 1998Date of Patent: September 28, 1999Assignee: Adir et CompagnieInventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Anne Dekeyne