Patents by Inventor Anne Dekeyne

Anne Dekeyne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8247441
    Abstract: The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: August 21, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Guillaume De Nanteuil, Bernard Cimetiere, Anne Dekeyne, Mark Millan
  • Publication number: 20110021490
    Abstract: The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.
    Type: Application
    Filed: July 20, 2010
    Publication date: January 27, 2011
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Guillaume De Nanteuil, Bernard Cimetiere, Anne Dekeyne, Mark Millan
  • Patent number: 7026357
    Abstract: Compound of formula (I): and medicinal products containing the same are useful as dual ?2/5-HT2c antagonist receptors.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: April 11, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Publication number: 20040224993
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: June 7, 2004
    Publication date: November 11, 2004
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6784183
    Abstract: Compounds of formula (I): and medicinal products containing the same which are useful as dual &agr;2/5-HT2c antagonists.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: August 31, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6747032
    Abstract: Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, alkoxy, polyhaloalkyl, hydroxy, cyano, nitro and amino,  or R1 with R2, R2 with R3, or R3 with R4, together with the carbon atoms carrying them, form an optionally substituted benzene ring or an optionally substituted heteroaromatic ring, X represents an oxygen atom or a methylene group, A represents an alkylene chain,  represents an optionally substituted, unsaturated, nitrogen-containing heterocycle and R5 represents an alkyl group, its enantiomers and diastereoisomers, and addition salts thereof with a pharmaceutically acceptable acid, a medicinal products containing the same are useful as a double &agr;2/5-HT2c antagonist.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: June 8, 2004
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Thierry Dubuffet, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Publication number: 20030087916
    Abstract: Compound of formula (I): 1
    Type: Application
    Filed: April 18, 2002
    Publication date: May 8, 2003
    Inventors: Gilbert Lavielle, Thierry Dubuffet, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6492366
    Abstract: A compound selected from those of formula (I): wherein: R1 and R2 each independently represent hydrogen or, alkyl, T1 and T2 each independently represent alkylene, G represents a heterocyclic group selected of formula (&agr;):  wherein: W1 to W5 and X1 to X4 are so defined in the description. Medicinal products containing the same are useful as serotonin-reuptake inhibitors.
    Type: Grant
    Filed: October 11, 2000
    Date of Patent: December 10, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Didier Cussac, Anne Dekeyne
  • Patent number: 6486171
    Abstract: A compound selected from those of formula (I): wherein: W represents optionally substituted naphthyl, or a group of formula Y (wherein)  as defined in the description, n represents an integer from 1 to 6 inclusive, Z represents a single bond, oxygen, or optionally substituted nitrogen, A and Q each represent CH or nitrogen, it being understood that A or Q must be N and the other CH, M, together with a carbon of the phenyl to which it is bonded, represents thienyl, furyl, pyrrolyl, or oxopyrrolyl, its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same, which are useful in the treatment of some CNS disorders.
    Type: Grant
    Filed: March 25, 2002
    Date of Patent: November 26, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Louis Peglion, Aimée Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
  • Publication number: 20020161228
    Abstract: A compound selected from those of formula (I): 1
    Type: Application
    Filed: March 25, 2002
    Publication date: October 31, 2002
    Applicant: ADIR ET COMPAGNIE
    Inventors: Jean Louis Peglion, Aimee Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
  • Patent number: 6399616
    Abstract: A compound selected from those of formula (I): wherein: W represents optionally substituted naphthyl, n represents an integer from 2 to 3 inclusive, Z represents a single bond, A represents nitrogen, Q represents nitrogen, M, together with the carbon of pyridyl to which it is bonded, represents thieno, furo, pyrrolo or oxopyrrolo, Its optical isomers and pharmaceutically-acceptable acid or base additional salts thereof, and Medicinal products containing the same which are useful in the treatment of CNS disorders. It being understood that “aryl” is phenyl, naphthyl, dihydronaphthyl, or tetrahydronaphthyl.
    Type: Grant
    Filed: August 18, 2000
    Date of Patent: June 4, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Louis Peglion, Aimée Dessinges, Christophe Poitevin, Mark Millan, Anne Dekeyne
  • Publication number: 20020025965
    Abstract: 1
    Type: Application
    Filed: June 29, 2001
    Publication date: February 28, 2002
    Inventors: Gilbert Lavielle, Olivier Muller, Mark Millan, Anne Dekeyne, Mauricette Brocco
  • Patent number: 6350757
    Abstract: A compound selected from those of formula (I): wherein: represents single or double bond, R1 represents hydrogen, alkyl, —R6-aryl, —R6-cycloalkyl, —R6-heterocycle, —CO2R7—, —COR8, or —CONHR8, wherein R6, R7, and R8 are as defined in the description, R2 represents cyano, mono- or di-alkylaminoalkylaminocarbonyl, —CO2R8, —CONHR8, —NR8R9, —NHCO2R7, or —COR8 wherein R7, R8, and R9 are as defined in the description, R3 and R4 together form (C3-C10)cycloalkyl, R5 represents hydrogen, alkyl, or arylalkyl, Ra, Rb, Rc, Rd, which may be identical or different, represent a group as defined in the description, its isomers, and pharmaceutically-acceptable acid or base addition salts thereof, and medicinal products containing the same which are useful in the treatment of CNS disorders.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: February 26, 2002
    Assignee: Les Laboratoires Servier
    Inventors: Solo Goldstein, Guillaume Poissonnet, Jean-Gilles Parmentier, Jean-Daniel Brion, Mark Millan, Anne Dekeyne, Jean Boutin
  • Patent number: 6153640
    Abstract: A compound of formula (I): ##STR1## wherein: R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, represent a group as defined in the description,R.sub.4 represents hydrogen, alky, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl, heterocycloalkyl, heterocycloalkylalkyl, heteroaryl, or heteroarylalkyl,R.sub.5 represents aryl, or heteroaryl, each optionally substituted,n is an integer from 1 to 3 inclusive,their isomers and addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same are usefull in the treatment of disease like depression, panic attacks, obsessive-compulsive disorders, phobias, impulsive disorders, drug abuse or anxiety.
    Type: Grant
    Filed: March 23, 2000
    Date of Patent: November 28, 2000
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Bertrand Goument, Aimee Dessinges, Mark Millan, Jean-Michel Rivet, Anne Dekeyne
  • Patent number: 6060487
    Abstract: A compound of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, X--Y, A, Z and Z' are as defined in the description, in the form of the cis or trans isomers each in racemic or optically active form, and acid addition salts thereof, and medicinal products containing the same are useful in the treatment of diseases of the central nervous system or of manifestations of pain.
    Type: Grant
    Filed: March 22, 1999
    Date of Patent: May 9, 2000
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Anne Dekeyne
  • Patent number: 5958927
    Abstract: A compound of formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, X-Y, A, Z and Z' are as defined in the description, in the form of the cis or trans isomers each in racemic or optically active form, and acid addition salts thereof, and medicinal products containing the same are useful in the treatment of diseases of the central nervous system or of manifestations of pain.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: September 28, 1999
    Assignee: Adir et Compagnie
    Inventors: Jean-Louis Peglion, Bertrand Goument, Mark Millan, Adrian Newman-Tancredi, Anne Dekeyne