Patents by Inventor Anne Eeg Knapp

Anne Eeg Knapp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Calcium sensing receptor modulating compounds and pharmaceutical use thereof
    Patent number: 8765676
    Abstract: Calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I (wherein X is CH or N) and pharmaceutical compositions thereof are useful for treating diseases.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: July 1, 2014
    Assignee: Leo Pharma A/S
    Inventors: Bjarne Nørremark, Lars Kristian Albert Blæhr, Anne Eeg Knapp, Kristoffer Månsson
  • NOVEL CALCIUM SENSING RECEPTOR MODULATING COMPOUNDS AND PHARMACEUTICAL USE THEREOF
    Publication number: 20120122784
    Abstract: The invention relates to novel calcium-sensing receptor (CaSR) modulating substituted cyclopentylene compounds represented in formula I and derivatives thereof, to said compounds for use as a medicament, to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases with said compounds, and to the use of said compounds in the manufacture of medicaments.
    Type: Application
    Filed: May 26, 2010
    Publication date: May 17, 2012
    Applicant: LEO PHARMA A/S
    Inventors: Bjarne Nørremark, Lars Kristian Albert Blæhr, Anne Eeg Knapp, Kristoffer Månsson
  • IMIDAZOL (1,2-A)PYRIDINES AND RELATED COMPOUNDS WITH ACTIVITY AT CANNABINOID CB2 RECEPTORS
    Publication number: 20110206607
    Abstract: Disclosed herein are compounds of Formula (I), or a pharmaceutically acceptable salt, ester, amide, thereof; and methods of modulating the activity of a cannabinoid CB2 receptor comprising contacting a compound of Formula I with the cannabinoid CB2 receptor. Also disclosed are methods of imaging of a tissue by positron emission tomography, the method comprising administering to the subject a compound of Formula I, wherein the compound comprises a radioisotope. Also disclosed are methods of measuring the relative concentration of cannabinoid CB2 receptors in tissue of a subject, by using a compound of Formula I which comprises a radioisotope. In addition, method of diagnosing a disorder in a subject are disclosed.
    Type: Application
    Filed: May 9, 2008
    Publication date: August 25, 2011
    Inventors: Roger Olsson, Ethan Burstein, Anne Eeg Knapp, Jorgen Eskildsen, Joel Castillo, James Nairne, Veronique Morisson-Iveson, Edward Robins, Alex Gibson
  • PAR2-modulating compounds and their use
    Publication number: 20080318960
    Abstract: The present invention relates to compounds, and uses thereof, having the chemical formula: or a pharmaceutically acceptable salt or prodrug thereof, wherein the compound modulates the activity of PAR2 or a PAR2 subtype and thereby may be used to treat or prevent diseases involving abnormal PAR2 or PAR2 subtype activity.
    Type: Application
    Filed: May 16, 2006
    Publication date: December 25, 2008
    Inventors: Ethan Burstein, Anne Eeg Knapp
  • COMPOUNDS FOR THE TREATMENT OF PAIN AND SCREENING METHODS THEREFOR
    Publication number: 20080249081
    Abstract: Disclosed herein are benzoimidazole compounds; pharmaceutical compositions comprising a therapeutically effective amount of the same; methods of modulating the activity of an MrgX1 or an MrgX2 receptor using the same; and methods of alleviating acute, chronic and neuropathic pain in a subject using the same. Also disclosed are methods of identifying a benzoimidazole compound that modulates the activity of an MrgX1 or an MrgX2 receptor; methods of identifying a benzoimidazole compound effective for the treatment of pain.
    Type: Application
    Filed: October 24, 2007
    Publication date: October 9, 2008
    Inventors: Roger Olsson, Anne Eeg Knapp, Jorgen Eskildsen