Abstract: An exemplary elevator braking device comprises a brake housing. A plurality of rollers are supported by the brake housing. The rollers are arranged to be positioned on opposite sides of a guiderail. The rollers are selectively moveable between a first position in which the rollers are spaced apart a first distance and a second position in which the rollers are spaced apart a second, smaller distance so that the rollers engage and roll along opposite sides of the guiderail. At least one biasing member is supported by the brake housing. The biasing member is associated with at least one of the rollers and biases the associated roller toward the other roller in the second position. A plurality of braking surfaces are supported by the brake housing. At least one braking surface is associated with each of the rollers. Each braking surface engages a periphery of the associated roller that faces the side of the guiderail.

Abstract: An elevator system includes one or more rails fixed in a hoistway and an elevator car configured to move through the hoistway along the one or more rails. The system includes one or more braking systems having one more braking surfaces secured to the elevator car and frictionally engageable with one or more rails of the elevator system. One or more actuators are operably connected to the one or more braking surfaces configured to urge engagement and/or disengagement of the one or more braking surfaces with the rail to stop and/or hold the elevator car during operation of the elevator system.

Abstract: An elevator system includes one or more rails fixed in a hoistway and an elevator car configured to move through the hoistway along the one or more rails. The system includes one or more braking systems having one more braking surfaces secured to the elevator car and frictionally engageable with one or more rails of the elevator system. One or more actuators are operably connected to the one or more braking surfaces configured to urge engagement and/or disengagement of the one or more braking surfaces with the rail to stop and/or hold the elevator car during operation of the elevator system.

Abstract: A method of determining a prognosis of a cancer in a human comprising: determining expression level of CHST11 in a cancer tissue sample or determining methylation status of CHST11 gene in a cancer tissue sample. CHST11 is Carbohydrate (Chondroitin 4) Sulfotransferase 11.

Abstract: A brake element is provided including a friction material. The friction material includes a polymer-based ceramic matrix composite material having a plurality of fibers. The plurality of fibers is arranged at an angle to a braking direction.

Abstract: An elevator system includes an electronic system capable of triggering a machine room brake and an electromagnetic safety trigger with low hysteresis and with minimal power requirements that can be released to engage safeties, when car over-speed and/or over-acceleration is detected. The electromagnetic trigger may be reset automatically and may be released to engage the safeties, during the reset procedure. The system includes a processing system that is configured to decrease response time and to reduce the occurrence of false triggers caused by conditions unrelated to passenger safety, such as passengers jumping inside the elevator car.

Abstract: An elevator system 40 includes an over-acceleration and over-speed protection system capable of triggering a machine room brake and a safety trigger when over-speed or over-acceleration conditions are detected. The system includes a speed detector 42 and an acceleration detector 44. Based upon sensed speed and sensed acceleration, the controller 48 calculates a filtered speed of an elevator mass such as an elevator car 16 or counterweight, and compares the filtered speed to the threshold speed to determine whether an over-speed condition has been reached. The controller 48 activates a machine room brake when an over-speed condition exists, and engages an elevator safety 70A, 70B when it determines that the elevator mass is still in an over-speed condition after the machine room brake has been activated.

Abstract: An electromagnetic safety trigger 46 includes a link 72 kinematically connected to a safety 70A, 70B of an elevator system mass, such as an elevator car or counterweight. An electromagnet 76 mounted on a linear actuator 74 is magnetically coupled to the link 72, and a spring 78 is connected between the link 72 and the elevator mass. The electromagnet 76 can be triggered to release the link 72, which allows the spring 78 to move the link 72 to engage the safety 70A, 70B.

Abstract: An elevator system includes one or more rails fixed in a hoistway and an elevator car configured to move through the hoistway along the one or more rails. The system includes one or more braking systems having one more braking surfaces secured to the elevator car and frictionally engageable with one or more rails of the elevator system. One or more actuators are operably connected to the one or more braking surfaces configured to urge engagement and/or disengagement of the one or more braking surfaces with the rail to stop and/or hold the elevator car during operation of the elevator system.

Abstract: An additive compound comprising a derivative of particular fatty acids and polyamines has been found to be friction reducing, and particularly readily miscible in fuels and lubricants. The fatty acid has more than 12 carbon atoms and at least one carboxylic group. The polyamine residue has more than two nitrogen atoms. The mole ratio of the carboxylic groups to nitrogen atoms used to form the compound is greater than 0.8 carboxylic groups per 1 nitrogen atom.

Abstract: An additive, comprising a fatty acid and/or a derivative of a fatty acid and an amine, is used in a fuel for the purpose of increasing the efficiency of an engine combusting said fuel, in particular for the purpose of reducing the losses arising from the sliding of the pistons of an engine within their cylinders, and preferably with the result that fuel economy is improved.

Abstract: An exemplary elevator braking device comprises a brake housing. A plurality of rollers are supported by the brake housing. The rollers are arranged to be positioned on opposite sides of a guiderail. The rollers are selectively moveable between a first position in which the rollers are spaced apart a first distance and a second position in which the rollers are spaced apart a second, smaller distance so that the rollers engage and roll along opposite sides of the guiderail. At least one biasing member is supported by the brake housing. The biasing member is associated with at least one of the rollers and biases the associated roller toward the other roller in the second position. A plurality of braking surfaces are supported by the brake housing. At least one braking surface is associated with each of the rollers. Each braking surface engages a periphery of the associated roller that faces the side of the guiderail.

Abstract: An elevator system 40 includes an electronic system 48 capable of triggering a machine room brake and an electromagnetic safety trigger 46 with low hysteresis and with minimal power requirements that can be released to engage safeties 70A, 70B when car over-speed and/or over-acceleration is detected. The electromagnetic trigger 46 may be reset automatically and may be released to engage the safeties 70A, 70B during the reset procedure. The system includes an over-speed and over-acceleration detection and processing system that is configured to decrease response time and to reduce the occurrence of false triggers caused by conditions unrelated to passenger safety, such as passengers jumping inside the elevator car 16.

Abstract: An elevator system 40 includes an over-acceleration and over-speed protection system capable of triggering a machine room brake and a safety trigger when over-speed or over-acceleration conditions are detected. The system includes a speed detector 42 and an acceleration detector 44. Based upon sensed speed and sensed acceleration, the controller 48 calculates a filtered speed of an elevator mass such as an elevator car 16 or counterweight, and compares the filtered speed to the threshold speed to determine whether an over-speed condition has been reached. The controller 48 activates a machine room brake when an over-speed condition exists, and engages an elevator safety 70A, 70B when it determines that the elevator mass is still in an over-speed condition after the machine room brake has been activated.

Abstract: An electromagnetic safety trigger 46 includes a link 72 kinematically connected to a safety 70A, 70B of an elevator system mass, such as an elevator car or counterweight. An electromagnet 76 mounted on a linear actuator 74 is magnetically coupled to the link 72, and a spring 78 is connected between the link 72 and the elevator mass. The electromagnet 76 can be triggered to release the link 72, which allows the spring 78 to move the link 72 to engage the safety 70A, 70B.

Abstract: The present invention provides animal models and methods for the evaluation of maternal treatments that could improve or compromise the epigenetic state, the imprinting, or the DNA methylation and thus the health or disease propensity, of human or other mammalian offspring. In particular, the present invention provides animal models with naturally occurring epigenetic variation for the evaluation of treatments through effects on the epigenetically determined and imprinted characteristics of coat color, coat color pattern, DNA methylation, long terminal repeat (LTR) expression and LTR activity of offspring.

Abstract: A brake mechanism (10) for an elevator (2) is activated in response to an electronic control signal to prevent movement of an elevator car (16) under predetermined conditions. The brake mechanism is preferably a safety mechanism (10) and does not require a governor sheave, a governor rope, or a tension sheave. The safety mechanism in one disclosed example utilizes a solenoid actuator (22b) and an electric motor (40) and gear box assembly (42) to move safety wedges (18) into engagement with a guide rail (20) to stop the elevator car (16). The safety wedges (18) are held in a non-deployed position during normal elevator operation. If there is a power loss or if elevator car speed exceeds a predetermined threshold, an electronic control signal activates the safety mechanism (10) causing the solenoid to release, which causes the safety wedges (18) move in a direction opposite to that of a safety housing (12) mounted for movement with the elevator car (16).

Abstract: A brake mechanism (10) for an elevator (2) is activated in response to an electronic control signal to prevent movement of an elevator car (16) under predetermined conditions. The brake mechanism is preferably a safety mechanism (10) and does not require a governor sheave, a governor rope, or a tension sheave. The safety mechanism in one disclosed example utilizes a solenoid actuator (22b) and an electric motor (40) and gear box assembly (42) to move safety wedges (18) into engagement with a guide rail (20) to stop the elevator car (16). The safety wedges (18) are held in a non-deployed position during normal elevator operation. If there is a power loss or if elevator car speed exceeds a predetermined threshold, an electronic control signal activates the safety mechanism (10) causing the solenoid to release, which causes the safety wedges (18) move in a direction opposite to that of a safety housing (12) mounted for movement with the elevator car (16).

Abstract: There is provided a friction modifier of the formula R1L-N(R2)(R3) wherein R1 is a hydrocarbyl group that has a number average molecular weight (Mn) of from 500 to 5000; L is an optional linker group; and R2 and R3 are independently selected from H, a hydrocarbyl group and a bond to optional group L, wherein at least one of R2 and R3 is H or a hydrocarbyl group, with the proviso that if one of R2 and R3 is a hydrocarbyl group and the other of R2 and R3 is H, the hydrocarbyl group does not contain a terminal amine.

Abstract: The present invention provides animal models and methods for the evaluation of maternal treatments that could improve or compromise the epigenetic state, the imprinting, or the DNA methylation and thus the health or disease propensity, of human or other mammalian offspring. In particular, the present invention provides animal models with naturally occurring epigenetic variation for the evaluation of treatments through effects on the epigenetically determined and imprinted characteristics of coat color, coat color pattern, DNA methylation, long terminal repeat (LTR) expression and LTR activity of offspring.