Patents by Inventor Anthony J. Berno
Anthony J. Berno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11031098Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.Type: GrantFiled: May 31, 2016Date of Patent: June 8, 2021Assignee: Genetic Technologies LimitedInventors: Nila Patil, David R. Cox, Anthony J. Berno, David A. Hinds
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Publication number: 20160371429Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.Type: ApplicationFiled: May 31, 2016Publication date: December 22, 2016Inventors: Nila Patil, David R. Cox, Anthony J. Berno, David A. Hinds
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Publication number: 20110020815Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.Type: ApplicationFiled: June 7, 2010Publication date: January 27, 2011Inventors: Nila Patil, David R. Cox, Anthony J. Berno, David A. Hinds
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Patent number: 7252948Abstract: This invention provides oligonucleotide based arrays and methods for speciating and phenotyping organisms, for example, using oligonucleotide sequences based on the Mycobacterium tuberculosis rpoB gene. The groups or species to which an organism belongs may be determined by comparing hybridization patterns of target nucleic acid from the organism to hybridization patterns in a database.Type: GrantFiled: February 4, 2005Date of Patent: August 7, 2007Assignee: Affymetrix, Inc.Inventors: Thomas R. Gingeras, David Mack, Mark S. Chee, Anthony J. Berno, Lubert Stryer, Ghassan Ghandour, Ching Wang
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Patent number: 7058657Abstract: An interactive and dynamic data analysis tool that helps interactive analysis in real time on medium size datasets having complex structure is described. In one aspect, the data analysis tool is capable of being configured to act as a data producer tool arranged to provide a data source. The data analysis tool can also be configured as a data consumer tool capable of receiving and processing a particular data source. The data source tool and the data consumer tool are connected together to form a framework that takes the form of a data mapping context that mediates the data provided by the data source and a particular data role.Type: GrantFiled: January 7, 2003Date of Patent: June 6, 2006Assignee: Perlegen Sciences, Inc.Inventor: Anthony J. Berno
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Patent number: 6969589Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.Type: GrantFiled: March 26, 2002Date of Patent: November 29, 2005Assignee: Perlegen Sciences, Inc.Inventors: Nila Patil, David R. Cox, Anthony J. Berno, David A. Hinds
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Patent number: 6924094Abstract: This invention provides oligonucleotide based arrays and methods for speciating and phenotyping organisms, for example, using oligonucleotide sequences based on the Mycobacterium tubercluosis rpoB gene. The groups or species to which an organism belongs may be determined by comparing hybridization patterns of target nucleic acid from the organism to hybridization patterns in a database.Type: GrantFiled: November 28, 2000Date of Patent: August 2, 2005Assignee: Affymetrix, Inc.Inventors: Thomas R. Gingeras, David Mack, Mark S. Chee, Anthony J. Berno, Lubert Stryer, Ghassan Ghandour, Ching Wang
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Patent number: 6694321Abstract: A schema-isolated system is disclosed for developing, modifying, or maintaining client applications that accesses target databases. The system includes a middleware-table inserter that inserts middleware tables into the target database. The middleware tables include a set of compatibility data relating one or more client-application data requests with one or more corresponding target-database data capabilities. The middleware tables also include a data communication component. This component receives a client-application data request from the client application, and, based on at least a first datum of the set of compatibility data, provides to the client application the one or more target-database data capabilities corresponding to the client-application data request. The first compatibility datum relates the one or more client-application data requests with the one or more corresponding target-database data capabilities based, at least in part, on an application-usage-independent criterion.Type: GrantFiled: September 22, 2000Date of Patent: February 17, 2004Assignee: Affymetrix, Inc.Inventor: Anthony J. Berno
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Publication number: 20040029161Abstract: The present invention relates to business methods for discovery of therapeutic and diagnostic products by identifying variations that occur in the human genome, relating these variations to one another, and, ultimately, relating these variations to the genetic bases of phenotype such as disease resistance, disease susceptibility or drug response.Type: ApplicationFiled: May 30, 2003Publication date: February 12, 2004Applicant: Perlegen Sciences, Inc.Inventors: David R. Cox, Nila Patil, Anthony J. Berno, David A. Hinds
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Publication number: 20040023275Abstract: The present invention relates to methods for identifying variations that occur in the human genome, relating these variations to one another, and, ultimately, relating these variations to the genetic bases of phenotype such as disease resistance, disease susceptibility or drug response. The methods allow for, once variants have been identified, determining variant haplotype blocks and patterns, and further, resolving ambiguities in the haplotype block and pattern data sets.Type: ApplicationFiled: April 29, 2003Publication date: February 5, 2004Applicant: Perlegen Sciences, Inc.Inventors: Anthony J. Berno, Nila Patil, David R. Cox, David A. Hinds
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Publication number: 20040024537Abstract: Systems and methods for detecting differences in sample polymers, such as nucleic acid sequences, are provided. Hybridization affinity information for the sample polymers is clustered so that the differences, if any, between or among the sample polymers can be readily identified. By clustering the hybridization affinity information of the sample polymers, differences in the sample polymers can be accurately achieved even in the presence of random and systematic errors.Type: ApplicationFiled: May 12, 2003Publication date: February 5, 2004Applicant: AFFYMETRIX, INC. a Corporation of the state of CaliforniaInventor: Anthony J. Berno
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Patent number: 6584410Abstract: Systems and methods for detecting differences in sample polymers, such as nucleic acid sequences, are provided. Hybridization affinity information for the sample polymers is clustered so that the differences, if any, between or among the sample polymers can be readily identified. By clustering the hybridization affinity information of the sample polymers, differences in the sample polymers can be accurately achieved even in the presence of random and systematic errors.Type: GrantFiled: January 16, 2001Date of Patent: June 24, 2003Assignee: Affymetrix, Inc.Inventor: Anthony J. Berno
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Publication number: 20030099964Abstract: The present invention relates to methods for identifying variations that occur in the human genome and relating these variations to the genetic basis of disease and drug response. In particular, the present invention relates to identifying individual SNPs, determining SNP haplotype blocks and patterns, and, further, using the SNP haplotype blocks and patterns to dissect the genetic bases of disease and drug response. The methods of the present invention are useful in whole genome analysis.Type: ApplicationFiled: March 26, 2002Publication date: May 29, 2003Applicant: Perlegen Sciences, Inc.Inventors: Nila Patil, David R. Cox, Anthony J. Berno, David A. Hinds
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Publication number: 20010041965Abstract: Systems and methods for detecting differences in sample polymers, such as nucleic acid sequences, are provided. Hybridization affinity information for the sample polymers is clustered so that the differences, if any, between or among the sample polymers can be readily identified. By clustering the hybridization affinity information of the sample polymers, differences in the sample polymers can be accurately achieved even in the presence of random and systematic errors.Type: ApplicationFiled: January 16, 2001Publication date: November 15, 2001Inventor: Anthony J. Berno
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Patent number: 6228575Abstract: This invention provides oligonucleotide based arrays and methods for speciating and phenotyping organisms, for example, using oligonucleotide sequences based on the Mycobacterium tuberculosis rpoB gene. The groups or species to which an organism belongs may be determined by comparing hybridization patterns of target nucleic acid from the organism to hybridization patterns in a database.Type: GrantFiled: February 7, 1997Date of Patent: May 8, 2001Assignee: Affymetrix, Inc.Inventors: Thomas R. Gingeras, David Mack, Mark S. Chee, Anthony J. Berno, Lubert Stryer, Ghassan Ghandour, Ching Wang
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Patent number: 6223127Abstract: Systems and methods for detecting differences in sample polymers, such as nucleic acid sequences, are provided. Hybridization affinity information for the sample polymers is clustered so that the differences, if any, between or among the sample polymers can be readily identified. By clustering the hybridization affinity information of the sample polymers, differences in the sample polymers can be accurately achieved even in the presence of random and systematic errors.Type: GrantFiled: August 14, 1998Date of Patent: April 24, 2001Assignee: Affymetrix, Inc.Inventor: Anthony J. Berno
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Patent number: 6171793Abstract: A genetic sample is analyzed by providing a gene probe array including a plurality of genetic probes having different receptors. The sample is processed to include at least one fluorescently tagged ligand. The array is hybridized by exposing the probes to the processed sample such that ligands can bind to complementary receptors. Composite data having a data dynamic range is obtained from the array using an optical scanner which has a scanner dynamic range that is smaller than the data dynamic range. The scanner optically irradiates and scans the probes and detects fluorescent emissions at a first wavelength which is selected such that the scanner produces valid first data in a low intensity portion of the data dynamic range and is in saturation in at least part of a high intensity portion of the data dynamic range.Type: GrantFiled: April 19, 1999Date of Patent: January 9, 2001Assignee: Affymetrix, Inc.Inventors: Vincent E. Phillips, Huu Minh Tran, Thomas Ryder, Anthony J. Berno, Ghassan Ghandour