Patents by Inventor Antonio Ortega-Martinez

Antonio Ortega-Martinez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11452479
    Abstract: A diagnostic system is provided for classifying a soft tissue condition within a region of interest of a subject. The diagnostic system comprises a spectrometer system configured to irradiate a soft tissue within a region of interest of a subject, and configured to generate spectral data by acquiring at least a portion of the reflected or emitted light from the region of interest. The diagnostic system further comprises a thermal detection system including at least one thermal sensor that is configured to acquire thermal detection data from the region of interest. A computer system is then used to build a classification model based on input thermal detection and spectral data. The classification model is then applied to an unknown soft tissue condition to classify the condition (e.g., classifying cellulitis from pseudocellulitis).
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: September 27, 2022
    Assignee: The General Hospital Corporation
    Inventors: Richard R. Anderson, Adam B. Raff, William A. Farinelli, Daniela Kroshinsky, Antonio Ortega-Martinez
  • Publication number: 20220242848
    Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.
    Type: Application
    Filed: November 23, 2021
    Publication date: August 4, 2022
    Applicants: Fondazione Istituto Italiano Di Tecnologia, The Regents of the University of California
    Inventors: Marco De Vivo, Anand Ganesan, Jose Antonio Ortega Martinez, Sohail Jahid
  • Publication number: 20220184008
    Abstract: The present invention relates to a compound of Formula la, lb and Ic, (Formula Ia) a pharmaceutical composition comprising the same and their use in the treatment or prevention of pathological conditions associated to depolarizing GABAergic transmission including, for example, Down syndrome and autism.
    Type: Application
    Filed: April 2, 2020
    Publication date: June 16, 2022
    Inventors: Laura Cancedda, Marco De Vivo, Andrea Contestabile, Marco Borgogno, Annalisa Savardi, Jose Antonio Ortega Martinez
  • Patent number: 11198682
    Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: December 14, 2021
    Assignees: Fondazione Istituto Italiano Di Tecnologia, The Regents of the University of California
    Inventors: Marco De Vivo, Anand Ganesan, Jose Antonio Ortega Martinez, Sohail Jahid
  • Patent number: 10889560
    Abstract: The present invention concerns 4-amino-2-pyrido-bicyclic pyrimidines of Formula (I) that function as type II topoisomerase inhibitors and their use thereof as medicaments especially in the treatment of cancer. The invention also provides a method for the manufacture of 4-amino-2-pyrido bicyclic pyrimidines of Formula (I).
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 12, 2021
    Assignees: UNIVERSITÀ DEGLI STUDI DI PADOVA, ALMA MATER STUDIORUM-UNIVERSITÀ DI BOLOGNA, FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA
    Inventors: Marco De Vivo, Jose Antonio Ortega Martinez, Jose Manuel Arencibia Jimenez, Anna Minarini, Claudia Sissi
  • Publication number: 20200121243
    Abstract: A diagnostic system is provided for classifying a soft tissue condition within a region of interest of a subject. The diagnostic system comprises a spectrometer system configured to irradiate a soft tissue within a region of interest of a subject, and configured to generate spectral data by acquiring at least a portion of the reflected or emitted light from the region of interest. The diagnostic system further comprises a thermal detection system including at least one thermal sensor that is configured to acquire thermal detection data from the region of interest. A computer system is then used to build a classification model based on input thermal detection and spectral data. The classification model is then applied to an unknown soft tissue condition to classify the condition (e.g., classifying cellulitis from pseudocellulitis).
    Type: Application
    Filed: April 5, 2018
    Publication date: April 23, 2020
    Inventors: Richard R. Anderson, Adam B. Raff, William A. Farinelli, Daniela Kroshinsky, Antonio Ortega-Martinez
  • Publication number: 20200062733
    Abstract: The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function.
    Type: Application
    Filed: May 2, 2018
    Publication date: February 27, 2020
    Applicants: Fondazione Istituto Italiano Di Tecnologia, The Regents of the University of California
    Inventors: Marco De Vivo, Anand Ganesan, Jose Antonio Ortega Martinez, Sohail Jahid
  • Publication number: 20190315709
    Abstract: The present invention concerns 4-amino-2-pyrido-bicyclic pyrimidines as type II topoisomerase inhibitors and use thereof as medicaments especially in the treatment of cancer. The invention also provides a method for the manufacture of 4-amino-2-pyrido bicyclic pyrimidines.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 17, 2019
    Inventors: Marco DE VIVO, Jose Antonio ORTEGA MARTINEZ, Jose Manuel ARENCIBIA JIMENEZ, Anna MINARINI, Claudia SISSI