Abstract: This invention relates to bioactive sol-gel derived silica fibers, methods for their preparation, an implantable device comprising said fibers and the use of said device for tissue guiding or bone repair.

Abstract: This invention relates to bioactive sol-gel derived silica fibers, methods for their preparation, an implantable device comprising the fibers and the use of the device for tissue guiding or bone repair.

Abstract: The invention relates to glass ionomer for enhancing mineralization of hard tissue of mammals. The glass ionomer comprises, a inert biocompatible ceramic and a bioactive ceramic. The invention also relates to a method for enhancing mineralization of hard tissue of mammals with the aid of said glass ionomer. The invention further relates to the use of said glass ionomer for the preparation of products intended for treatment of defects of soft and hard tissue as well as the use of said glass ionomer for the preparation of a variety of products wherein the ability to enhance mineralization is advantageous.

Abstract: The invention relates to a material suitable for the reconstruction of an individual's tissue, in particular supportive tissue such as bone tissue, insertable into the tissue. It is characteristic that it is made up of wood heat-treated within the temperature range of 100-220° C. in the presence of water vapor. The invention also relates to the use of the material.

Abstract: A porous textile product made from bioactive glass fibers. The fibers in the product are of at least two types, fiber A and fiber B, with fiber A being made from a bioactive glass, and fiber B being made from a weakly bioactive glass.

Abstract: The present invention is concerned with controllably dissolvable silica-xerogels prepared via sol-gel process and their use. Specifically, the invention is concerned with a delivery device comprising controllably dissolvable silica-xerogel into which structure a biologically active agent is incorporated. The invention is further concerned with pharmaceutical preparations comprising said delivery device. Further, the invention is directed to medical devices for orthopedic and surgical purposes comprising controllably dissolvable silica-xerogels, which may further comprise a biologically active agent.

Abstract: The invention relates to a method for reducing the viability of detrimental oral microorganisms in an individual, said method comprising subjecting the individual's oral cavity to a bioactive glass, the average particle size of which is less than 100 &mgr;m.

Abstract: This invention relates to bioactive sol-gel derived silica fibers, methods for their preparation, an implantable device comprising said fibers and the use of said device for tissue guiding or bone repair.

Abstract: A composite intended for medical use, in particular surgical or therapeutic use, characterized in that it comprises a mixture of a thermoplastic component plasticizable within the temperature range −10° . . . +100° C., which is substantially made up of hydroxy acids and structural units derived from hydroxy acid derivatives and the molar mass of which is within the range 30,000-1,000,000 g/mol, and which degrades in the body typically within a period ranging from a few days to several years, and which in its solid state is a mechanically strong plastic or rubbery material, and a bioactive component, which is a bioactive glass or a bioactive xerogel, such that the plasticized thermoplastic component remains moldable for a certain period even after the temperature of the composite has been lowered to a temperature which is considerably lower than the setting temperature of said thermoplastic component.

Abstract: The invention relates to a method for reducing the viability of detrimental oral microorganisms in an individual, said method comprising subjecting the individual's oral cavity to a bioactive glass, the average particle size of which is less than 100 &mgr;m. Furthermore, this invention concerns a method for the prevention of dental caries and/or gingivitis in an individual, said caries being caused by a cariogenic bacteria; or for prevention or treatment of periapical infections. Further the invention relates to a method for the whitening and/or mechanical cleaning of an individual's teeth.

Abstract: The invention relates to a porous textile product made from bioactive glass fibers.

Abstract: The invention relates to a porous composite which comprises particles made from a bioactive material, the particles being sintered together to form a porous composite. It is characteristic that the particles have one or more recesses or throughgoing holes, or that the particles provided with an unbroken surface layer are hollow.

Abstract: A porous composite suitable for filling a recess or a through-passing hole in an implant. The composite includes particles A prepared from a bioactive material and particles B prepared from a non-bioactive material or weakly bioactive material, which is sintratable with the bioactive material, such that particles A and particles B have been sintered together to a porous composite. Particles A and particles B are essentially homogeneous in size. Also disclosed is an implant which contains a core and the composite.

Abstract: This invention relates to a shapable prepreg comprising fibers and a polymeric matrix. The polymeric matrix is a multiphase matrix comprising a first matrix component consisting of a monomer or a dendrimer, and a second matrix component consisting of high molecular weight organic molecules, said second matrix component forming a sticky membrane of the prepreg with an interpenetrating polymer network (IPN) bonding to the first matrix component. Preferably, the prepreg further comprises a third matrix component consisting of high molecular weight organic molecules, said third component being distributed between the fibers.

Abstract: The invention relates to a method for reducing the viability of detrimental oral microorganisms in an individual, said method comprising subjecting the individual's oral cavity to a bioactive glass, the average particle size of which is less than 100 &mgr;m. Furthermore, this invention concerns a method for the prevention of dental caries and/or gingivitis in an individual, said caries being caused by a cariogenic bacteria; or for prevention or treatment of periapical infections. Further the invention relates to a method for the whitening and/or mechanical cleaning of an individual'teeth.

Abstract: The invention relates to a bioactive glass having a suitable working range for glass processing. Said bioactive glass comprises oxides of silicon, phosphorus, alkalis, alkaline earths and optionally other elements such as boron. According to the invention said oxides are present in the following amounts: SiO.sub.2 53-60 wt. %; Na.sub.2 O 0-34 wt. %; K.sub.2 O 1-20 wt. %; MgO 0-5 wt. %; CaO 5-25 wt. %; B.sub.2 O.sub.3 0-4 wt. %; P.sub.2 O.sub.5 0.5-6 wt. %; provided that Na.sub.2 O+K.sub.2 O=16-35 wt. %; K.sub.2 O+MgO=5-20 wt. % and MgO+CaO=10-25 wt. %.

Abstract: A pharmaceutical preparation, including a glass phase which is bioactive silica containing glass in the form of a paste, suspension or solution mixed in a physiologically suitable liquid or bound to a physiologically suitable vehicle, and which preparation reduces the pulpal irritation or a tooth and/or strengthens the structure of a tooth. Bioactive silica containing glass may be a material which contains only Si-oxide or Si-hydroxide and which allows the formation and movement of Si--OH-groups. Preferably, the preparation also contains calcium and phosphate sources.

Abstract: A bioceramic system for delivery of a bioactive compound, which comprises a combination of bioactive glass, bioactive glass ceramic or bioactive ceramic, hydroxyapatite, optionally one or more other calcium phosphate compound and optionally a matrix, and which may incorporate into the bioceramic system a bioactive compound. The timing of the release of the bioactive compound can be regulated as desired and depends on the conditions of the surrounding, the composition of the bioceramic system and its method preparation.

Abstract: An implant for replacing a tooth or another part of bony tissue comprises a first non-resorbable layer (2) containing a bioglass, e.g., CaP-glass; a second layer (4) of a mixture of bioglass and hydroxyl apatite resorbable into bone or biomass, and a slowly resorbable intermediate layer (3) containing bioglass and being disposed between said first and second layers; the inclusion of said hydroxyl apatite into the second layer (4) securing the stability of bonding of the implant to the tissue. When strength is required, the implant further comprises a metal core (1) to which the first layer (2) is attached. The materials may also be used as a granule filler in bone cavities and as a block for the replacement of bone.