Patents by Inventor Aquilur Rahman

Aquilur Rahman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20160324857
    Abstract: The present application discloses a method of treating a Varicella-Zoster Virus (VZV) infection in an individual in need thereof, including the step of administering to said individual an effective Varicella-Zoster Virus antiviral amount of a compound called N-methanocarbathymidine (N-MCT), which has a northern configuration with the structure as follows
    Type: Application
    Filed: May 3, 2016
    Publication date: November 10, 2016
    Inventors: Jennifer MOFFAT, DONGMEI LIU, WANDA COOMBS, MICHAEL APPEL, AQUILUR RAHMAN
  • Patent number: 9298420
    Abstract: A circuit for identifying one or more bit positions of instances of a selected bit value in an N-bit input bit string includes a plurality of adders that compute, in parallel, sums of bits in each of P input substrings comprising the input bit string. A plurality of zero position detectors detect, for each of the P input substrings for which a corresponding sum differs from a threshold sum, one or more bit positions of the selected bit value. Correction logic generates adjustment indications indicative of a number of detected instances of the selected bit value. A plurality of output substring adjusters that, based on the detected bit positions and the adjustment indications, collectively output one or more output vectors identifying a bit position of at least an Mth instance of the selected bit value in the input bit string.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: March 29, 2016
    Assignee: International Business Machines Corporation
    Inventors: Akif A. Ali, Aquilur Rahman, Salim A. Shah
  • Publication number: 20150032786
    Abstract: A circuit for identifying one or more bit positions of instances of a selected bit value in an N-bit input bit string includes a plurality of adders that compute, in parallel, sums of bits in each of P input substrings comprising the input bit string. A plurality of zero position detectors detect, for each of the P input substrings for which a corresponding sum differs from a threshold sum, one or more bit positions of the selected bit value. Correction logic generates adjustment indications indicative of a number of detected instances of the selected bit value. A plurality of output substring adjusters that, based on the detected bit positions and the adjustment indications, collectively output one or more output vectors identifying a bit position of at least an Mth instance of the selected bit value in the input bit string.
    Type: Application
    Filed: July 26, 2013
    Publication date: January 29, 2015
    Inventors: AKIF A. ALI, Aquilur Rahman, Salim A. Shah
  • Patent number: 8425115
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, first linear conductive members are positioned in a first IC layer, in parallel relationship with one another. Second linear conductive members are positioned in a second IC layer in parallel relationship with one another. Conductive elements connect the first linear members into a first conductive path, and the second linear members into a second conductive path. A third conductive element extending between the first and second layers connects the first and second conductive paths into a single conductive path, wherein the path resistance varies with temperature. The path resistance is used to determine temperature.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: April 23, 2013
    Assignee: International Business Machines Corporation
    Inventors: Aquilur Rahman, Lloyd A. Walls
  • Publication number: 20110176579
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, first linear conductive members are positioned in a first IC layer, in parallel relationship with one another. Second linear conductive members are positioned in a second IC layer in parallel relationship with one another. Conductive elements connect the first linear members into a first conductive path, and the second linear members into a second conductive path. A third conductive element extending between the first and second layers connects the first and second conductive paths into a single conductive path, wherein the path resistance varies with temperature. The path resistance is used to determine temperature.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 21, 2011
    Applicant: International Business Machines Corporation
    Inventors: Aquilur Rahman, Lloyd Andre Walls
  • Patent number: 7946763
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, a plurality of first linear conductive members are positioned in a first IC layer, in spaced-apart parallel relationship with one another. A plurality of second linear conductive members are similarly positioned in a second IC layer in spaced-apart parallel relationship with one another, and in orthogonal relationship with the first linear members or in parallel with existing wiring channels of the second IC layer. Conductive elements respectively connect the first linear members into a first conductive path, and the second linear members into a second conductive path.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: May 24, 2011
    Assignee: International Business Machines Corporation
    Inventors: Aquilur Rahman, Lloyd Andre Walls
  • Publication number: 20090135883
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, a plurality of first linear conductive members are positioned in a first IC layer, in spaced-apart parallel relationship with one another. A plurality of second linear conductive members are similarly positioned in a second IC layer in spaced-apart parallel relationship with one another, and in orthogonal relationship with the first linear members or in parallel with existing wiring channels of the second IC layer. Conductive elements respectively connect the first linear members into a first conductive path, and the second linear members into a second conductive path.
    Type: Application
    Filed: January 30, 2009
    Publication date: May 28, 2009
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Aquilur Rahman, Lloyd Andre Walls
  • Patent number: 7510323
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, a conductive element extending between first and second layers for connecting said first and second conductive paths into a single continuous conductive path having a resistance that varies with temperature. The sensor is responsive to electric current sent through said continuous path for determining temperature proximate to said continuous path from said path resistance.
    Type: Grant
    Filed: March 14, 2006
    Date of Patent: March 31, 2009
    Assignee: International Business Machines Corporation
    Inventors: Aquilur Rahman, Lloyd Andre Walls
  • Patent number: 7442520
    Abstract: A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC-3 such as breast cancer and lung cancer.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: October 28, 2008
    Assignee: Georgetown University
    Inventors: Usha Kasid, Prafulla Gokhale, Deepak Kumar, Howard Boudreau, Imran Ahmad, Anatoly Dritschilo, Aquilur Rahman
  • Patent number: 7390502
    Abstract: The present invention is for novel compositions and methods for treating diseases caused by cellular proliferation, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include SN-38 lipid complexes in which the complexes can contain any of a variety of neutral or charged lipids and, desirably, cardiolipin. The compositions are capable of efficiently incorporating SN-38 into complexes and are capable of solubilizing relatively high concentrations of SN-38.
    Type: Grant
    Filed: April 28, 2003
    Date of Patent: June 24, 2008
    Assignee: NeoPharm, Inc.
    Inventors: Imran Ahmad, Jia-Ai Zhang, Aquilur Rahman
  • Publication number: 20070215973
    Abstract: A compact resistive thermal sensor is provided for an integrated circuit (IC), wherein different sensor components are placed on different layers of the IC. This allows the lateral area needed for the sensor resistance wire on any particular IC layer to be selectively reduced. In a useful embodiment, a plurality of first linear conductive members are positioned in a first IC layer, in spaced-apart parallel relationship with one another. A plurality of second linear conductive members are similarly positioned in a second IC layer in spaced-apart parallel relationship with one another, and in orthogonal relationship with the first linear members or in parallel with existing wiring channels of the second IC layer. Conductive elements respectively connect the first linear members into a first conductive path, and the second linear members into a second conductive path.
    Type: Application
    Filed: March 14, 2006
    Publication date: September 20, 2007
    Inventors: Aquilur Rahman, Lloyd Walls
  • Patent number: 7262173
    Abstract: The invention relates to the use of oligonucleotide containing cationic liposomal formulations to enhance the efficacy of chemotherapy and/or radiotherapy, particularly as a means to sensitize cancerous tumor tissues to the efficiencies of chemotherapy. This is particularly advantageous in the context of treating raf expressing tumors such as breast, lung, pancreatic and prostate tumors.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: August 28, 2007
    Assignees: Georgetown University, NeoPharm, Inc.
    Inventors: Usha Kasid, Prafulla Gokhale, Jin Pei, Rajshree Mewani, Imran Ahmad, Anatoly Dritschilo, Aquilur Rahman
  • Patent number: 7253272
    Abstract: A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC2 such as breast cancer and lung cancer.
    Type: Grant
    Filed: October 6, 2003
    Date of Patent: August 7, 2007
    Assignee: Georgetown University
    Inventors: Usha Kasid, Prafulla Gokhale, Deepak Kumar, Constantinos Broustas, Imran Ahmad, Anatoly Dritschilo, Aquilur Rahman
  • Publication number: 20070104718
    Abstract: A gene that is a modulator of tumor growth and metastasis in certain cancer types is provided. This gene and corresponding polypeptide have diagnostic and therapeutic application for detecting and treating cancers that involve expression of BRCC-1 such as breast cancer and lung cancer.
    Type: Application
    Filed: September 28, 2006
    Publication date: May 10, 2007
    Inventors: Prafulla Gokhale, Anatoly Dritschilo, Aquilur Rahman, Imran Ahmad, Usha Kasid
  • Patent number: 7122553
    Abstract: The present invention is for novel compositions and methods for treating cancer, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include liposome entrapped irinotecan in which the liposome can contain any of a variety of neutral or charged liposome-forming compounds and cardiolipin. The liposomes of the present invention can be either multilamellar vesicles and unilamellar vesicles, as desired.
    Type: Grant
    Filed: November 19, 2003
    Date of Patent: October 17, 2006
    Assignee: NeoPharm, Inc.
    Inventors: Aquilur Rahman, Imran Ahmad
  • Publication number: 20060141020
    Abstract: It is possible to radiosensitize tumor cells by administration of compositions containing the Human antisense c-raf-1 oligodeoxyribonucleotide (ODN/oligo) sequence: 5?-GTGCTCCATTGATGC-3? (SEQ. ID. NO: 1) wherein only the end bases are phosphorothioated is a preferred embodiment. Antisense sequences of up to 40 bases which contain this sequence, such as 5?-CCTGTATGTGCTCCATTGATGCAGC-3? (SEQ ID NO: 2) may be used in accord with the teachings of this disclosure. Compositions comprising a cationic liposome of dimethyldioctadecyl ammonium bromide, phosphatidylcholine and cholesterol may be used as a carrier system. The liposomes provide a new carrier system that is particularly useful for administration of sequences for therapy.
    Type: Application
    Filed: December 10, 2004
    Publication date: June 29, 2006
    Applicant: Georgetown University
    Inventors: Usha Kasid, Prafulla Gokhale, Chuanbo Zhang, Anatoly Dritschilo, Aquilur Rahman
  • Patent number: 6970798
    Abstract: For testing a device under test (“DUT”) a test specification is converted in a computer system by a pin vector generator process, which includes generating test vectors. The DUT has numerous input pins and such a pin vector is for a signal to drive one such pin. The pin vectors are compressed and saved. Ones of the pin vectors are loaded, upon initialization of a test, into a pipeline having a series of memory stages and extending from the computer system to channel cards in a test head. The pipeline is operated in data transfer cycles, delivering W bits per cycle. The pin vectors are decompressed at the respective channel cards in decompressor read cycles. X bits are read per decompressor cycle, W being greater than X, so that the pipeline may perform its data transfer cycles less frequently than the decompressor performs its read cycles.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: November 29, 2005
    Assignee: International Business Machines Corporation
    Inventors: Tai Anh Cao, Khanh Nguyen, Aquilur Rahman
  • Publication number: 20050251359
    Abstract: For testing a device under test (“DUT”) a test specification is converted in a computer system by a pin vector generator process, which includes generating test vectors. The DUT has numerous input pins and such a pin vector is for a signal to drive one such pin. The pin vectors are compressed and saved. Ones of the pin vectors are loaded, upon initialization of a test, into a pipeline having a series of memory stages and extending from the computer system to channel cards in a test head. The pipeline is operated in data transfer cycles, delivering W bits per cycle. The pin vectors are decompressed at the respective channel cards in decompressor read cycles. X bits are read per decompressor cycle, W being greater than X, so that the pipeline may perform its data transfer cycles less frequently than the decompressor performs its read cycles.
    Type: Application
    Filed: May 6, 2004
    Publication date: November 10, 2005
    Applicant: International Business Machines Corporation
    Inventors: Tai Cao, Khanh Nguyen, Aquilur Rahman
  • Publication number: 20050202074
    Abstract: Liposomal-encapsulated taxane or an antineoplastic derivative thereof or a mixture thereof is provided which is used to effect a therapeutically enhanced method of treating cancer. The liposomal encapsulated paclitaxel allows for administration to a patient, particularly a human patient, in less than one hour without substantial toxicity.
    Type: Application
    Filed: October 7, 2002
    Publication date: September 15, 2005
    Applicant: NEOPHARM, INC.
    Inventor: Aquilur Rahman
  • Publication number: 20050019387
    Abstract: The present invention is for novel compositions and methods for treating cancer, particularly, for treating cancer in mammals and more particularly in humans. The therapeutic compositions of the present invention include liposome entrapped irinotecan in which the liposome can contain any of a variety of neutral or charged liposome-forming compounds and cardiolipin. The liposomes of the present invention can be either multilamellar vesicles and unilamellar vesicles, as desired.
    Type: Application
    Filed: November 19, 2003
    Publication date: January 27, 2005
    Applicant: NeoPharm, Inc.
    Inventors: Aquilur Rahman, Imran Ahmad