Patents by Inventor Arash Soheili

Arash Soheili has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A Method of Treating Cancer
    Publication number: 20090012061
    Abstract: The present invention relates to a method of treating cellular proliferative diseases, in particular cancer, which comprises administering a modulator of the activity of the mitotic kinesin KSP, wherein the activity of the KSP modulator is dependent on the presence of microtubules. It is believed that the KSP modulators utilized in the instant method bind to the KSP protein in a previously unreported manner, since the compounds do not bind competitively with respect to either microtubules or ATP, the substrates of KSP. The modulators useful in the instant methods are furthermore not active against the non-microtubule stimulated activity of KSP. Cellular proliferative diseases that may be treated using the method disclosed herein are, for example cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation.
    Type: Application
    Filed: September 9, 2005
    Publication date: January 8, 2009
    Inventors: Timothy A. Blizzard, Carolyn A. Buser-Doepner, Douglas E. Frantz, Kelly Hamilton, Myle Hoang, Ling Lee, Christopher R. Moyes, Jerry A. Murry, Arash Soheili
  • Method of preparing inhibitors phosphodiesterase-4
    Patent number: 7312334
    Abstract: In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula (V), which are useful in making inhibitors of phosphodiesterase-4: The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula (IX, IXa).
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: December 25, 2007
    Assignee: Merck & Co. Inc.
    Inventors: Jennifer Albaneze-Walker, Jerry Anthony Murry, Arash Soheili, Shawn A. Springfield
  • Method of preparing inhibitors phosphodiesterase-4
    Publication number: 20060019981
    Abstract: In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula (V), which are useful in making inhibitors of phosphodiesterase-4: The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula (IX, IXa)
    Type: Application
    Filed: November 18, 2003
    Publication date: January 26, 2006
    Inventors: Jennifer Albaneze-Walker, Jerry Murry, Arash Soheili, Shawn Springfield
  • Method of preparing inhibitors of phosphodiesterase-4
    Patent number: 6909002
    Abstract: In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula V, which are useful in making inhibitors of phosphodiesterase-4: The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula
    Type: Grant
    Filed: October 21, 2003
    Date of Patent: June 21, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Jennifer Albaneze-Walker, Scott Ceglia, Jerry Anthony Murry, Arash Soheili
  • Method of preparing inhibitors of phosphodiesterase-4
    Publication number: 20040102472
    Abstract: In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula V, which are useful in making inhibitors of phosphodiesterase-4: 1
    Type: Application
    Filed: October 21, 2003
    Publication date: May 27, 2004
    Inventors: Jennifer Albaneze-Walker, Scott Ceglia, Jerry Anthony Murry, Arash Soheili