Patents by Inventor Arlette Darfeuille-Michaud

Arlette Darfeuille-Michaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating induced inflammatory bowel diseases such as crohn's disease
    Patent number: 10632135
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: April 28, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Julie Bouckaert, Sebastien Gouin, Adeline Sivignon, Arlette Darfeuille-Michaud, Rostyslav Bilyy, Dimitri Alvarez-Dorta, Nao Yamakawa, Tetiana Dumych
  • ORALLY AVAILABLE COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS ANTI-ADHESIVE DRUGS FOR TREATING E. COLI INDUCED INFLAMMATORY BOWEL DISEASES SUCH AS CROHN'S DISEASE
    Publication number: 20190374559
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Inventors: Julie BOUCKAERT, Sebastien GOUIN, Adeline SIVIGNON, Arlette DARFEUILLE-MICHAUD, Rostyslav BILYY, Dimitri ALVAREZ-DORTA, Nao YAMAKAWA, Tetiana DUMYCH
  • Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating induced inflammatory bowel diseases such as crohn's disease
    Patent number: 10485811
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Grant
    Filed: January 23, 2015
    Date of Patent: November 26, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AUVERGNE, UNIVERSITE DES SCIENCES ET TECHNOLOGIES DE LILLE 1, UNIVERSITE DE NANTES, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Julie Bouckaert, Sebastien Gouin, Adeline Sivignon, Arlette Darfeuille-Michaud, Rostyslav Bilyy, Dimitri Alvarez-Dorta, Nao Yamakawa, Tetiana Dumych
  • Multimeric mannosides, a process for preparing the same and their uses as a drug
    Patent number: 10273313
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia coli infections.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: April 30, 2019
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE NANTES, UNIVERSITE DE PICARDIE JULES VERNE, UNIVERSITE LILLE 1-SCIENCES ET TECHNOLOGIES, UNIVERSITE D'AUVERGNE
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • ORALLY AVAILABLE COMPOUNDS, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS ANTI-ADHESIVE DRUGS FOR TREATING E. COLI INDUCED INFLAMMATORY BOWEL DISEASES SUCH AS CROHN'S DISEASE
    Publication number: 20160340445
    Abstract: Orally available compounds, a process for preparing the same and their uses as anti-adhesive drugs for treating E. coli induced inflammatory bowel diseases such as crohn's disease.
    Type: Application
    Filed: January 23, 2015
    Publication date: November 24, 2016
    Inventors: Julie BOUCKAERT, Sebastien GOUIN, Adeline SIVIGNON, Arlette DARFEUILLE-MICHAUD (Deceased), Rostyslav BILYY, Dimitri ALVAREZ-DORTA, Nao YAMAKAWA, Tetiana DUMYCH
  • METHOD FOR DIAGNOSING AND TREATING CROHN'S DISEASE
    Publication number: 20160091501
    Abstract: The present invention relates to an in vitro method for diagnosing Crohn's disease or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk of developing the disease. The invention also relates to preventive or curative treatment for Crohn's disease.
    Type: Application
    Filed: September 30, 2015
    Publication date: March 31, 2016
    Inventors: Nicolas BARNICH, Arlette Darfeuille-Michaud, Anne-Lise Glasser
  • Method for diagnosing and treating Crohn's disease
    Patent number: 9176131
    Abstract: The invention concerns an in vitro method for diagnosing Crohn's disease, or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk. The invention also concerns preventive or curative treatment of Crohn's disease.
    Type: Grant
    Filed: October 13, 2005
    Date of Patent: November 3, 2015
    Assignee: LESAFFRE ET COMPAGNIE
    Inventors: Nicolas Barnich, Arlette Darfeuille-Michaud, Anne-Lise Glasser
  • MULTIMERIC MANNOSIDES, A PROCESS FOR PREPARING THE SAME AND THEIR USES AS A DRUG
    Publication number: 20150210781
    Abstract: The present invention relates to multimeric mannosides, a process for preparing the same and their uses in medicine for treating Escherichia Coli infections.
    Type: Application
    Filed: July 24, 2013
    Publication date: July 30, 2015
    Inventors: Julie Bouckaert, Sebastien Gouin, David Deniaud, Rostyslav Bilyy, Tetiana Dumych, Adeline Sivignon, Arlette Darfeuille-Michaud
  • Antagonists for the prevention or treatment of inflammatory bowel disease, and more particularly of Crohn's disease
    Patent number: 8974789
    Abstract: An antagonist of the interaction between the Gp96 receptor and E. coli AIEC strains, for the prevention or treatment of inflammatory bowel disease. The antagonist is for specifically blocking or reducing the interaction between Gp96 receptor and the outer membrane vesicles (OMVs), typically the outer protein membrane OmpA of E. coli AIEC strains. The inventions provides for pharmaceutical compositions containing such an antagonist, which may be an antibody against gp96 or OmpA, or a gp96 or OmpA polypeptide. It may be combined to an antagonist of the interaction between the CEACAM6 receptor and E. coli AIEC strains, such as an anti-CEACAM6 antibody, a CEACAM6 polypeptide, or a mannoside or particle having a mannose unit. The invention also relates to a method for the diagnosis of inflammatory bowel disease, or of the determination of a predisposition of a person to develop inflammatory bowel disease.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: March 10, 2015
    Assignee: Universite d'Auvergne Clermont I
    Inventors: Arlette Darfeuille-Michaud, Paul Hofman, Nathalie Rolhion
  • Probiotic yeast compositions and methods for inflammatory diseases
    Patent number: 8476058
    Abstract: The invention relates to novel yeast strains, to the yeasts resulting from these strains, to a composition containing at least one Saccharomyces cerevisiae yeast and/or derivatives of a yeast having a particular interest as a food additive and/or probiotic and/or functional food and/or neutraceutic and/or functional ingredient and/or cosmeceutical and/or pharmaceutical active agent. The invention also relates to the use of the same in human and/or animal nutrition, or for the treatment or prevention of inflammatory diseases.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: July 2, 2013
    Assignees: Lesaffre et Compagnie, Universite du Droit et de la Sante Lille 2, Universite d 'Auvergne Clermont 1
    Inventors: Jean-Luc Simon, Georges Pignede, Pascal Vandekerckove, Pierre Desreumaux, Daniel Poulain, Arlette Darfeuille-Michaud, Adeline Sivignon
  • Antagonists for the Prevention of Treatment of Inflammatory Bowel Disease, and More Particularly of Crohn's Disease
    Publication number: 20130084292
    Abstract: An antagonist of the interaction between the Gp96 receptor and E. coli AIEC strains, for the prevention or treatment of inflammatory bowel disease. The antagonist is for specifically blocking or reducing the interaction between Gp96 receptor and the outer membrane vesicles (OMVs), typically the outer protein membrane OmpA of E. coli AIEC strains. The inventions provides for pharmaceutical compositions containing such an antagonist, which may be an antibody against gp96 or OmpA, or a gp96 or OmpA polypeptide. It may be combined to an antagonist of the interaction between the CEACAM6 receptor and E. coli AIEC strains, such as an anti-CEACAM6 antibody, a CEACAM6 polypeptide, or a mannoside or particle having a mannose unit. The invention also relates to a method for the diagnosis of inflammatory bowel disease, or of the determination of a predisposition of a person to develop inflammatory bowel disease.
    Type: Application
    Filed: April 15, 2011
    Publication date: April 4, 2013
    Applicant: UNIVERSITE D'AUVERGNE CLERMONT I
    Inventors: Arlette Darfeuille-Michaud, Paul Hofman, Nathalie Rolhion
  • COMPOSITION FOR HUMAN AND/OR ANIMAL NUTRITION, USES THEREOF AND YEASTS
    Publication number: 20100303778
    Abstract: The invention relates to novel yeast strains, to the yeasts resulting from these strains, to a composition containing at least one Saccharomyces cerevisiae yeast and/or derivatives of a yeast having a particular interest as a food additive and/or probiotic and/or functional food and/or neutraceutic and/or functional ingredient and/or cosmeceutical and/or pharmaceutical active agent. The invention also relates to the use of the same in human and/or animal nutrition, or for the treatment or prevention of inflammatory diseases.
    Type: Application
    Filed: December 12, 2008
    Publication date: December 2, 2010
    Inventors: Jean-Luc Simon, Georges Pignede, Pascal Vandekerckove, Daniel Poulain, Pierre Desreumaux, Arlette Darfeuille-Michaud, Adeline Sivignon
  • METHOD FOR DIAGNOSING AND TREATING CROHN'S DISEASE
    Publication number: 20100015600
    Abstract: The invention concerns an in vitro method for diagnosing Crohn's disease, or for determining predisposition in a person to develop Crohn's disease, by detecting an overexpression of the CD66c receptor in subjects suffering from said disease or at risk. The invention also concerns preventive or curative treatment of Crohn's disease.
    Type: Application
    Filed: October 13, 2005
    Publication date: January 21, 2010
    Inventors: Nicolas Barnich, Arlette Darfeuille-Michaud, Anne-Lise Glasser