Patents by Inventor Artem Plekhov

Artem Plekhov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibiting G protein coupled receptor 6 kinase polypeptides
    Patent number: 10252984
    Abstract: This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: April 9, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Keith Stewart, Artem Plekhov, Robert Greenhouse
  • Compositions comprising thienopyrimidine and thienopyridine compounds and methods of use thereof
    Patent number: 10160769
    Abstract: The present disclosure relates generally to thienopyrimidine and thienopyridine compounds and methods of use thereof. In particular embodiments, the present disclosure provides compositions comprising thienopyrimidine and thienopyridine compounds of Formula 3: and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: December 25, 2018
    Assignee: The Regents of the University of Michigan
    Inventors: Jolanta Grembecka, Tomasz Cierpicki, Dmitry Borkin, Jay L. Hess, Duxin Sun, Xiaoqin Li, Kevin Greenman, Mohamed Ibrahim, Artem Plekhov
  • Small molecule inhibitors of G protein coupled receptor 6 kinases polypeptides
    Patent number: 9902739
    Abstract: This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: February 27, 2018
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Keith Stewart, Brian Rich, Nikolai Sepetov, Robert Greenhouse, Artem Plekhov, Wen Yang, Zhiwei Tong
  • SMALL MOLECULE INHIBITORS OF G PROTEIN COUPLED RECEPTOR 6 KINASES POLYPEPTIDES
    Publication number: 20170050979
    Abstract: This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.
    Type: Application
    Filed: April 21, 2015
    Publication date: February 23, 2017
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Alexander Keith Stewart, Brian Rich, Nikolai Sepetov, Robert Greenhouse, Artem Plekhov, Wen Yang, Zhiwei Tong
  • Inhibiting G Protein Coupled Receptor 6 Kinase Polypeptides
    Publication number: 20140309185
    Abstract: This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies, inflammation diseases, and autoimmune disorders.
    Type: Application
    Filed: October 26, 2012
    Publication date: October 16, 2014
    Inventors: Alexander Keith Stewart, Artem Plekhov, Robert Greenhouse