Patents by Inventor Arul M. Chinnaiyan

Arul M. Chinnaiyan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090047269
    Abstract: The present invention relates to cancer markers. In particular, the present invention provides metabolites that are differentially present in prostate cancer and methods of inhibiting the growth of a cell by altering the level of such metabolites.
    Type: Application
    Filed: August 15, 2008
    Publication date: February 19, 2009
    Applicant: The Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Arun Sreekumar
  • Publication number: 20090012031
    Abstract: The present invention relates to therapeutic targets for cancer. In particular, the present invention relates to small molecules and nucleic acids that target EZH2 expression in prostate cancer.
    Type: Application
    Filed: July 3, 2008
    Publication date: January 8, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Arul M. Chinnaiyan, Sooryanarayana Lnu, Qi Cao
  • Publication number: 20080280771
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of the phosphorylation status of protein samples, including the generation and analysis of protein microarrays.
    Type: Application
    Filed: June 19, 2007
    Publication date: November 13, 2008
    Applicant: Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Manoj Pal, Arun Sreekumar, Stephen P. Ethier
  • Publication number: 20080222741
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of prostate cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
    Type: Application
    Filed: October 25, 2007
    Publication date: September 11, 2008
    Applicant: The Regents of the University of Michigan
    Inventor: Arul M. Chinnaiyan
  • Publication number: 20080153711
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
    Type: Application
    Filed: June 20, 2007
    Publication date: June 26, 2008
    Applicant: Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Manoj Pal, Arun Sreekumar, Stephen P. Ethier
  • Patent number: 7332290
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostate cancers. In particular, the present invention provides methods and compositions for the detection of ?-methylacyl-CoA racemase (AMACR) in the urine as a marker for prostate cancer detection.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: February 19, 2008
    Assignee: The Regents of the University of Michigan
    Inventors: Mark A. Rubin, Arul M. Chinnaiyan, Bharathi Laxman, Arun Sreekumar
  • Patent number: 7229774
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of prostate cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: June 12, 2007
    Assignee: Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Mark A. Rubin, Arun Sreekumar
  • Publication number: 20040214233
    Abstract: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of protein samples. The present invention thus provides improved methods for the separation and analysis of samples containing a plurality of proteins (e.g., cells).
    Type: Application
    Filed: January 13, 2004
    Publication date: October 28, 2004
    Applicant: The Regents of the University of Michigan
    Inventors: David M. Lubman, Arul M. Chinnaiyan, Arun Sreekumar, Bharathi Laxman, Fang Yan
  • Publication number: 20030175736
    Abstract: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. Genes identified as cancer markers using the methods of the present invention find use in the diagnosis and characterization of prostate cancer. In addition, the genes provide targets for cancer drug screens and therapeutic applications.
    Type: Application
    Filed: August 1, 2002
    Publication date: September 18, 2003
    Applicant: The Regents of the University of Michigan
    Inventors: Arul M. Chinnaiyan, Mark A. Rubin, Arun Sreekumar
  • Publication number: 20020122806
    Abstract: The invention provides compositions and methods for imaging cells and tissues in vivo and in situ. Compositions and methods are provided for administration to enhance the imaging of cells and tissues by, e.g., computer assisted tomography (CAT), magnetic resonance spectroscopy (MRS), magnetic resonance imaging (MRI), positron emission tomography (PET), single-photon emission computed tomography (SPECT), or bioluminescence imaging (BLI). Thus, the invention provides compositions and methods for identifying sites of primary and metastatic tumors and tumor neovasculature.
    Type: Application
    Filed: March 5, 2001
    Publication date: September 5, 2002
    Inventors: Arul M. Chinnaiyan, Alnawaz Rehemtulla, Brian D. Ross