Abstract: An apparatus for treating neonatal jaundice is in the form of a garment (10, 40) which has semiconductor light sources (14, 214, 314) affixed thereto for radiating toward the "inside" of the garment when the infant is dressed in the garment. A portable energy source such as batteries (318) or a fuel cell (360) powers the array of light sources. A method according to the invention vests the infant in the garment, and energizes the light sources by coupling a battery to the light sources, or fueling and starting the fuel cell. The therapy is continued for as long as desired or needed.

Abstract: The invention provides apparatuses for detecting light from, for example, closely spaced detection sites. In one embodiment, the invention provides an apparatus for measuring the amount of light emitted from or transmitted through two or more detection sites of a first set of detection sites on a planar substrate while spatially resolving the measurements for each detection site of the first set, the apparatus comprising: for each detection site of the first set, an addressable source of a light beam directed to that detection site at a first angle; and an array detector comprising a plurality of light responsive pixels, wherein for each detection site of the first set there is at least one light responsive pixel that receives light emitted from or transmitted through that detection site at a second angle that can be the same as the first angle.

Abstract: The invention provides apparatuses for detecting light from, for example, closely spaced detection sites.

Abstract: A medical probe device comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissue. The stylet comprises an electrical central conductor which is enclosed within an insulating or dielectric sleeve surrounded by a conductive layer terminated by an antenna to selectively deliver microwave or radio frequency energy to target tissue. One embodiment includes the electrical conductor being enclosed within a non-conductive sleeve which itself is enclosed within a conductive sleeve in a coaxial cable arrangement to form a microwave transmission line terminated by an antenna. Another embodiment includes a resistive element near the distal end of the stylet which couples the center electrode to an outer conductor to generate joulian heat as electromagnetic energy is applied, such as an RF signal.

Abstract: The catheter sensing and ablation arrangement allows location and cardiac abalation on a patient. The arrangement includes an electrically nonconductive catheter body, with a guide-wire lumen. The guidewire is electrically conductive, and, when the guidewire is assembled with the catheter, extends through the lumen, and is slideable therein. The guidewire has an enlarged distal end which, when retracted, blocks the guidewire lumen. The distal end of the catheter body has an exposed first electrode, which is connected to a terminal located near the proximal end. An action potential sensor is adapted for, in a sensing mode of operation, coupling to the proximal end of the guide wire and to the electrical terminal, for sensing action potentials appearing between the enlarged end of the guide wire and the first electrode, so the end of the guide wire may be moved to a cardiac location identifiable by the action potentials.

Abstract: A medical probe device comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissue. The stylet comprises an electrical central conductor which is enclosed within an insulating or dielectric sleeve surrounded by a conductive layer terminated by an antenna to selectively deliver microwave or radio frequency energy to target tissue. One embodiment includes the electrical conductor being enclosed within a non-conductive sleeve which itself is enclosed within a conductive sleeve in a coaxial cable arrangement to form a microwave transmission line terminated by an antenna. Another embodiment includes a resistive element near the distal end of the stylet which couples the center electrode to an outer conductor to generate joulian heat as electromagnetic energy is applied, such as an RF signal.

Abstract: A medical probe apparatus comprising a catheter having a stylet guide housing with at least one stylet port in a side thereof and stylet guide means for directing a flexible stylet outward through at least one stylet port and through intervening tissue to targeted tissues. The stylet guide has an integrated circuit or semiconductor apparatus at the distal end thereof to generate electromagnetic radiation directly at the point of the desired target tissue. The stylet includes at least one semiconductor or integrated circuit radiation emitter adapted for electromagnetic radiation when electrically energized. An elongated electrical insulator includes proximal and distal ends adapted to be introduced into a body opening, such as the urethra. First and second elongated electrical conductors are electrically isolated by the insulator.

Abstract: An optically coupled FET comprised of bottom layer, a top layer in which FET is formed and an intermediate layer having a waveguide communicating with a grating in registration with the FET.

Abstract: Dental or endodontic instruments such as drills, files, rasps, broaches, reamers, and the like are arranged to allow radiation of electromagnetic energy into a man-made or natural cavity in the tooth under treatment. The energy may be in the form of microwave or radio-frequency (RF) radiation. The energy raises the temperature of the surrounding tooth material, which tends to disinfect the material as a direct consequence of the temperature. Also, if a disinfectant material is additionally introduced into the tooth cavity, the temperature of the disinfectant material itself may be raised, which enhances its activity. In the particular application to the removal of degenerated pulp, the instrument may be introduced, and electrical or electromagnetic power applied to coagulate the pulp about the instrument, allowing more complete removal of the pulp. The dental instrument may be used with an RF energy delivery system for application of particular amounts of energy per unit time (power).

Abstract: An improved assembly for steering and orienting a functional element at the distal end of a catheter tube holds the functional element with its major axis aligned with the axis of the catheter tube for convenient steering to a tissue site. The mechanism can also pivot the functional element in response to an external force to orient the major axis of the functional element generally parallel to the plane of the tissue site, without bending the catheter tube.

Abstract: Fatty tissue involved in a liposuction procedure is treated with microwave energy (also known as RF). In a particular embodiment of the invention, the microwave energy is applied by means of a catheter including a suction lumen, an electromagnetic transmission line, and an antenna coupled to the distal end of the transmission line. A microwave generator coupled to the distal end of the transmission line causes radiation from the antenna into the fatty tissue adjacent to the distal suction port of the suction lumen, which tissue is thereby heated and softened. The softened fatty tissue is more readily detached from the adjacent tissue than in the absence of heat, and less mechanical force is required for removal. In another embodiment of the invention, the transmission line is formed so that the electromagnetic field extends into the suction lumen, so that the fatty tissue being removed therethrough continues to be heated.

Abstract: An angioplasty catheter includes a coaxial transmission line with an elongated center conductor and outer conductor. The transmission line terminates at the distal end in an antenna and a balloon. A longitudinal central bore through the center conductor is dimensioned to accept the guide filament. The center conductor is made from a metallized TEFLON polytetrafluoroethylene fluorocarbon tube.

Abstract: A multipurpose catheter apparatus for microwave aided balloon angioplasty includes a balloon capable of being filled with a lossy dielectric liquid, and bearing a metallization pattern. The catheter includes an electromagnetic transmission line. Radio frequency energy applied to the proximal end of the electromagnetic transmission line is radiated by an antenna within the balloon. The metallization pattern causes a portion of the energy applied to the proximal end of the transmission line to be reflected, which affects a characteristic such as impedance, return loss or time of reflection. A measurement apparatus measures the characteristic, and the distention of the balloon is determined from the measured characteristic. A guide filament may extend through the transmission line.

Abstract: A waveguide having walls defining an opening. An optically transmissive aperture in one wall allows light from an optical illumination source such as a laser diode array to illuminate the opening in which is located a semiconductor slab positioned to be illuminated. When the array illuminates the slab, the propagation characteristics (phase velocity and attenuation constant) of the waveguide changes. A continuous wave signal passing through the waveguide is thus attenuated and phase shifted. The laser array may be pulsed on and off while still maintaining the altered propagation constant.

Abstract: A photon energy activated PIN diode is reverse biased by a continuously supplied direct current voltage. The PIN diode is rendered conductive for passage of a radio frequency input signal when it is illuminated. Continuous illumination of the PIN diode is not required for conduction such that illumination may be pulsed on and off while the diode remains conductive.

Abstract: A catheter includes at least two electrical conductors extending from the proximal to the distal ends. A semiconductor chip generator of electromagnetic radiation is located at the distal end and is energized by electrical power supplied by the electrical conductors. The chip may be a laser or include an oscillator for generating electromagnetic radiation at a selected frequency or frequencies. In one embodiment, two chip radiation generators are located distally, each connected to one of the conductors. A third conductor is connected in common to both chips, whereby they may be energized independently. An axial aperture may be provided for a guide wire. A balloon may surround the distal end of the catheter, and may be inflated by way of another axial aperture.

Abstract: A light-activated PIN diode switch arrangement is coupled to a source of direct voltage and to a load for control of the flow of load current. The PIN diode switch arrangement is connected so as to be electrically reverse-biased, so that no current flows therethrough. A source of light is coupled to the active portion of the PIN diode switch arrangement for rendering it conductive when flooded with light. High power and low inductance is provided by a configuration in which two PIN diode sets are physically and electrically connected together in a physical and electrical stack by a conductive heat sink. Laser diode arrays above and below the diodes of the stack selectively illuminate the intrinsic region of each diode bath through the adjacent doped region and also directly through the side of the diode.

Abstract: An amplifying apparatus has a plurality of series coupled laser diodes that impedance match a signal source impedance and which are optically coupled to at least one PIN diode that impedance matches a load impedance. A high DC voltage is applied to the PIN diode so that gain is obtained and signal power is applied to the load. A plurality of parallel coupled PIN diodes can be used or a series-parallel combination.

Abstract: An electrical short-circuit for alternating-current (ac) microwave signals is physically positionable in direct response to an electrical bias control without an intermediary electromechanical converter. The electrically positionable short circuit includes at least first and second doped regions in a semiconductor, separated by a region in which the short circuit is formed between the doped regions by the bias. A first embodiment comprises discrete diodes connected between conductors at different locations, the discrete diodes having different forward junction voltages, so that varying the common bias voltage varies the number of conducting diodes and thus positions the short circuit in a stepwise manner.

Abstract: A light-activated PIN diode switch arrangement is coupled to a source of direct voltage and to a load for control of the flow of load current. The PIN diode switch arrangement is connected so as to be electrically reverse-biased, so that no current flows therethrough. A source of light is coupled to the active portion of the PIN diode switch arrangement for rendering it conductive when flooded with light. Higher reverse voltage capability, higher operating speed and lower overall forward resistance are simultaneously achieved by a plurality of series-connected PIN diodes by comparison with a single large PIN diode.