Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.

Abstract: The present invention relates to the use of compounds of formula (I) 1

Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.

Abstract: The present invention relates to the use of compounds of formula (I) 1

Abstract: The instant invention discloses a process for the synthesis of substituted indole cell proliferation inhibitors.

Abstract: The present invention relates to processes for preparing amine substituted benzofurans, and more particularly 4-(2-{2-[(2R)-2-methyl-1-pyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile, and salts thereof. Compounds prepared by the processes of the invention have demonstrated activity as histamine-3 receptor ligands.

Abstract: The present invention is a block oriented control system that allows interoperability between devices made by different manufacturers. A block oriented control system is a system which includes a plurality of field devices incorporating a physical layer, communication stack, and user layer, with the field devices being connected by a transmission medium, such as a bus. The physical layer receives signals from the bus and translates the signals into a message for the communications stack, and receives messages from the communications stack and translates the messages into signals for the bus. The communication stack controls the communications between devices operating in the control system. The user layer is a block oriented approach to the system's control functions, and includes function blocks and system management. The function blocks are standardized encapsulations of control functions, such as analog input or proportional/derivative.

Abstract: The instant invention discloses a process for the synthesis of substituted indole cell proliferation inhibitors.

Abstract: A process for the preparation of neuraminidase inhibitors having structural formula (28) 1

Abstract: The present invention is a block oriented control system that allows interoperability between devices made by different manufacturers. A block oriented control system is a system which includes a plurality of field devices incorporating a physical layer, communication stack, and user layer, with the field devices being connected by a transmission medium, such as a bus. The physical layer receives signals from the bus and translates the signals into a message for the communications stack, and receives messages from the communications stack and translates the messages into signals for the bus. The communication stack controls the communications between devices operating in the control system. The user layer is a block oriented approach to the system's control functions, and includes function blocks and system management. The function blocks are standardized encapsulations of control functions, such as analog input or proportional/derivative.

Abstract: Disclosed is an improved and efficient process for N-desmethylating the 3'-amino nitrogen of erythromycins and for converting the 3'-N-desmethylated erythromycins into 3'-N-substituted derivatives of 8,9-anhydro-erythromycin 6,9-hemiketals.

Abstract: A catalyst comprising 70-99% by wt. of cobaltic salt and 1-30% by wt. of ferric salt, the acid component of the salt being such as acetate; propionate; naphthenate adipate and phthalate; a process for preparing the above catalyst, and a process for the preparation of carboxylic acids by oxidation of a hydrocarbon with oxygen or air in the presence of the above catalyst.

Abstract: A method of making shaped bodies of silicon carbide, of graphite coated with silicon carbide or of a graphite-like material with a silicon carbide surface wherein a graphitic body is assembled from preformed parts in the desired shape and is immersed, under a chemically inert atmosphere, in a silicon melt and after penetration of the melt into gaps between abutting surfaces of the body and after reaction of the silicon with the graphite or the graphite-like material to form silicon carbide at the junctions, the body is removed from the melt and is cooled in a chemically inert atmosphere.

Abstract: Porous silicon carbide bodies are obtained by starting with a powder of particle size falling within a single sieve mesh range fraction and consisting either entirely of carbon particles or a mixture of carbon and silicon carbide particles of the same mesh fraction is mixed or coated with 15 to 30% by weight of a binder, moulded to shape, warmed in the temperature range from 40.degree. to 200.degree. C. to vaporize volatile material and then coked at a temperature rising to 850.degree. C. Then it is siliconized by raising the temperature to the range from 1650.degree. to 1950.degree. C. with gaseous silicon or impregnated with silicon by dipping the body into a silicon melt and convert it to carbide, with the excess silicon thereafter being removed by vaporizing out or by boiling in lye. Sieve mesh fractions in the region of a few hundred .mu.m are preferred, and the density of the porous body after pressing but before siliconizing should lie in the neighborhood of 0.6 to 0.7 g/cm.sup.3.

Abstract: For joining molded parts having silicon carbide surfaces, the surfaces are first roughened to a depth of about 100-500 .mu.m by removal of the free silicon either by vaporization or by etching when treating silicon containing silicon carbide layers containing at least 15% weight of excessive silicon. In the alternative, when no excessive silicon is present, the roughening can be done by laser shots pitting the surface. The pores provided by such a step are then loaded with carbon by (repeated) application of a cokable resin followed by coking, said resin can be soaked into the pores or attached as silicon containing resin wafer of cokable material. The surfaces to be joined are united and are heated, preferably at from 1600.degree. to 1800.degree. C. in the presence of silicon that is either made available at the edges of the joint as a liquid or else has been provided in the joint by a synthetic resin foil in which silicon powder is dispersed.

Abstract: Component bodies of silicon carbide base material, at least in their surface layers, are welded together without the provision of a binder at finely polished joining surfaces by virtue of the fact that at least one of the joint surfaces is of a silicon carbide material containing an excess of silicon (SiSiC). The component bodies are kept closely fitted together especially by an additional pressing force of at least 0.1 kg/cm.sup.2 during a heating stage at atmospheric or lower pressure at a temperature in the range from 1500.degree. C. to 1800.degree. C. for 15 to 100 minutes in an inert atmosphere, the excess of silicon at the boundary making it possible for silicon carbide crystal growth to take place across the boundary.

Abstract: A price-setting control device for a vending machine can be used to set prices for a number of products and to store those prices in a memory. A decimal-type visual display selectively, but simultaneously, displays a "line" number which is assigned to a given product plus the price set for that product. A line-selecting switch, rather than the customer-operated switches of the vending machine, is used to select the desired line number when the price, for the product corresponding to that line number, is to be set. Mode-controlling data for the operation of the vending machine can be stored in selected locations within the memory; and the line-selecting switch plus a price-setting switch can be used to change that data.

Abstract: A significant improvement of the silicon impregnation depth of a carbon precursor body in the siliconizing thereof to make a silicon carbide body is obtained, as well as an accelerated conversion into silicon carbide if activated carbon is used in whole or in part as the carbon powder component of the precursor body. The molding material is preferably 20 to 60% by weight of binder and 20 to 70% activated carbon. This molding material may also usefully contain 10 to 60% by weight of .alpha.-silicon carbide, which may be previously made by siliconizing carbon powder.

Abstract: A control device for a vending machine for setting prices and storing prices in a memory with a price-setting mode, a price verification mode and a product-vending mode. In the product-vending mode, actuation of a selection switch provides a momentary pulse through the vending circuit to enable a price to be loaded into a register for subsequent comparison with accumulated credit. That pulse is so short that a product is not vended; but it is sufficiently large to keep leakage from simulating it. Switches select the locations in memory where prices are stored, and further switches are provided to set the prices in those locations. The control device automatically responds to actuation of any of these switches to shift from the product-vending to the price-setting mode. Coin tube inventory switches are provided which have a dual function, namely, effecting emptying of the coin tubes and also placing the control device in the price verification mode.

Abstract: In the production of shaped silicon-carbide bodies, especially tubes which onsist predominantly of silicon carbide throughout their thickness for use in nuclear-reactor technology, a carbon-containing preform (body of the desired shape) is contacted with elemental silicon powder at a temperature of 1400.degree. C. to 1500.degree. C. and the silicon-contacted carbon-containing body is thereafter treated at a temperature of 1800.degree. C. to 2000.degree. C. to transform at least the major part of the carbon into silicon carbide.