Patents by Inventor Ashok V. Purandare

Ashok V. Purandare has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic toll-like receptor 7 (TLR7) agonists
    Patent number: 11485741
    Abstract: Compounds having a structure according to formula are modulators of TLR7 activity and can be used to treat conditions amenable to treatment by the modulation of TLR7 activity.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: November 1, 2022
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Ashok V. Purandare, Honghe Wan, Liqi He, Sanjeev Gangwar, Shoshana L. Posy, Yam B. Poudel, Prasanna Sivaprakasam, Naidu S. Chowdari
  • MACROCYCLIC TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS
    Publication number: 20210053979
    Abstract: Compounds having a structure according to formula are modulators of TLR7 activity and can be used to treat conditions amenable to treatment by the modulation of TLR7 activity.
    Type: Application
    Filed: April 23, 2019
    Publication date: February 25, 2021
    Inventors: Ashok V. PURANDARE, Honghe WAN, Liqi HE, Sanjeev GANGWAR, Shoshana L. POSY, Yam B. POUDEL, Prasanna SIVAPRAKASAM, Naidu S. CHOWDARI
  • JAK2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer
    Patent number: 8673933
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: March 18, 2014
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ashok V. Purandare, James W. Grebinski, Amy C. Hart, Jennifer Inghrim, Gretchen M. Schroeder, Honghe Wan
  • JAK2 INHIBITORS AND THEIR USE FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND CANCER
    Publication number: 20130225551
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: April 30, 2012
    Publication date: August 29, 2013
    Inventors: Ashok V. Purandare, James W. Grebinski, Amy Hart, Jennifer Inghrim, Gretchen Schroeder, Honghe Wan
  • JAK2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer
    Patent number: 8202881
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Grant
    Filed: September 2, 2010
    Date of Patent: June 19, 2012
    Assignee: Bristol-Meyers Squibb Company
    Inventors: Ashok V. Purandare, James W. Grebinski, Amy Hart, Jennifer Inghrim, Gretchen Schroeder, Honghe Wan
  • JAK2 INHIBITORS AND THEIR USE FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND CANCER
    Publication number: 20110059943
    Abstract: The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases.
    Type: Application
    Filed: September 2, 2010
    Publication date: March 10, 2011
    Inventors: Ashok V. Purandare, James W. Grebinski, Amy Hart, Jennifer Inghrim, Gretchen Schroeder, Honghe Wan
  • Antagonists of chemokine receptors
    Patent number: 7202249
    Abstract: Compounds are provided which are antagonists of chemokine receptor activity.
    Type: Grant
    Filed: August 25, 2003
    Date of Patent: April 10, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventor: Ashok V. Purandare
  • Antagonists of chemokine receptors
    Publication number: 20040048865
    Abstract: Compounds are provided which are antagonists of chemokine receptor activity.
    Type: Application
    Filed: August 25, 2003
    Publication date: March 11, 2004
    Inventor: Ashok V. Purandare
  • 5-HT7 receptor antagonists
    Patent number: 6630469
    Abstract: Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or centrally and peripherally mediated hypertension are provided.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: October 7, 2003
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Ashok V. Purandare, Ronald J. Mattson, Li-Qiang Sun
  • 5-HT7 receptor antagonists
    Publication number: 20020032199
    Abstract: Amino-pyrimidine and amino-triazine derivatives having 5-HT7 antagonist activity for the treatment of sleeping disorders, depression, schizophrenia, anxiety, obsessive compulsive disorders, circadian rhythm disorders, ocular disorders and/or centrally and peripherally mediated hypertension are provided.
    Type: Application
    Filed: April 24, 2001
    Publication date: March 14, 2002
    Inventors: Michael A. Poss, Ashok V. Purandare, Ronald J. Mattson, Li-Qiang Sun