Patents by Inventor Aurelio Romeo

Aurelio Romeo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8293312
    Abstract: A tomato composition obtained from tomato juice having the following composition in percentage by weight: dry residue>20% up to 99%, water<80% down to 1%; 100% being the sum of the two components, wherein the among of water insoluble solids in the dry residue ranges in percentage by weight from 18% to 70%.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: October 23, 2012
    Assignee: Zanichelli Ricerche S.R.L.
    Inventor: Aurelio Romeo
  • Publication number: 20100136193
    Abstract: Tomato products obtained from tomato juice or tomato passata having the following composition in percentage by weight: dry residue ?5.5-20%, water 94.5-80%, 100% being the sum of the two components, wherein the amount of water insoluble and water soluble solids in the dry residue ranges in percentage by weight: Water insoluble solids from 18% to 70%, Water soluble solids from 82% to 30%, the sum of the two components being 100% of the dry residue.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 3, 2010
    Inventor: Aurelio ROMEO
  • Patent number: 7709040
    Abstract: A process for treating tomato concentrates obtainable by concentration by evaporation, having a dry residue in percentage by weight higher than 15%, generally at least of about 18%, comprising the following steps: I) mixing of the tomato concentrate (component a)) with water (component b)); II) liquid separation by a separation solid-liquid apparatus, wherein the mass to be filtered is maintained under a slow stirring; III) addition of water and/or serum to the solid mass obtained in II).
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: May 4, 2010
    Assignee: Zanichelli Ricerche S.R.L.
    Inventor: Aurelio Romeo
  • Patent number: 7635496
    Abstract: Tomato products obtained from tomato juice or tomato passata having the following composition in percentage by weight: dry residue 5.5-20%, water 94.5-80%, 100% being the sum of the two components, wherein the amount of water-insoluble and water-soluble solids in the dry residue ranges in percentage by weight: Water-insoluble solids from 18% to 70% Water-soluble solids from 82% to 30%, the sum of the two components being 100% of the dry residue.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: December 22, 2009
    Assignee: Zanichelli Richerche S.R.I.
    Inventor: Aurelio Romeo
  • Publication number: 20080206428
    Abstract: A tomato composition obtained from tomato juice having the following composition in percentage by weight: dry residue >20% up to 99%, water <80% down to 1%; 100% being the sum of the two components, wherein the among of water insoluble solids in the dry residue ranges in percentage by weight from 18% to 70%.
    Type: Application
    Filed: January 25, 2005
    Publication date: August 28, 2008
    Inventor: Aurelio Romeo
  • Publication number: 20080206438
    Abstract: A process for treating tomato concentrates obtainable by concentration by evaporation, having a dry residue in percentage by weight higher than 15%, generally at least of about 18%, comprising the following steps: I) mixing of the tomato concentrate (component a)) with water (component b)); II) liquid separation by a separation solid-liquid apparatus, wherein the mass to be filtered is maintained under a slow stirring; III) addition of water and/or serum to the solid mass obtained in II).
    Type: Application
    Filed: January 25, 2005
    Publication date: August 28, 2008
    Inventor: Aurelio Romeo
  • Publication number: 20060035002
    Abstract: Tomato products obtained from tomato juice or tomato passata having the following, composition in percentage by weight: —dry residue 5.5-20%, —water 94.5-80%, 100% being the sum of the two components, wherein the amount of water insoluble and water soluble solids in the dry residue ranges in percentage by weight: —water insoluble solids from 18% to 70%. —Water soluble solids from 82% to 30% The sum of the two components being 100% of the dry residue.
    Type: Application
    Filed: August 5, 2003
    Publication date: February 16, 2006
    Inventor: Aurelio Romeo
  • Patent number: 6620792
    Abstract: The present invention refers to pharmaceutical compositions containing monosialoganglioside GM1 or a derivative thereof, namely, the inner ester AGF2 and the methyl ester AGF4, suitable for the treatment of Parkinson's disease. A further object of the present invention is a therapy for Parkinson's disease based on the associated administration of the aforesaid compounds and, in addition, the N-dichloroacetyl lyso GM1 (LIGA 20) with known pharmaceuticals active in the aforesaid treatment, in particular with L-dopa and/or BDNF.
    Type: Grant
    Filed: September 12, 1994
    Date of Patent: September 16, 2003
    Assignee: Fidia S.p.A.
    Inventors: Gino Toffano, Aurelio Romeo, Stephen Drake Skaper
  • Patent number: 6533820
    Abstract: The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in association with a pharmacologically active compound wherein the molecular weight of the hyaluronic acid is below 250,000 and either artificial or natural bone granules. The present invention further involves a method of promoting the growth or repair of damaged or defective bones in either humans or animals using the compositions of hyaluronic acid derivatives and bone granules.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: March 18, 2003
    Assignee: Fidia S.p.A.
    Inventors: Franco Dorigatti, Lanfranco Callegaro, Aurelio Romeo
  • Patent number: 6407072
    Abstract: Novel N-acyl-lysogangliosides obtained from gangliosides by deacyation of the ceramide group, wherein the acyl group is derived from an aliphatic acid having from 2 to 24 carbon atoms, substituted by one or more polar groups. The N-acyl-lysogangliosides of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.
    Type: Grant
    Filed: June 30, 1994
    Date of Patent: June 18, 2002
    Assignee: Fidia S.p.A.
    Inventors: Francesco Della Valle, Aurelio Romeo
  • Publication number: 20010053938
    Abstract: The present invention involves compositions for use as granular bone replacements. The compositions of the present invention are comprised of hyaluronic acid esters or salts of hyaluronic acid in association with a pharmacologically active compound wherein the molecular weight of the hyaluronic acid is below 250,000 and either artificial or natural bone granules. The present invention further involves a method of promoting the growth or repair of damaged or defective bones in either humans or animals using the compositions of hyaluronic acid derivatives and bone granules.
    Type: Application
    Filed: June 18, 1999
    Publication date: December 20, 2001
    Applicant: RAYMOND C. STEWART
    Inventors: FRANCO DORIGATTI, LANFRANCO CALLEGARO, AURELIO ROMEO
  • Patent number: 6224857
    Abstract: Pharmaceutical preparations are described, comprised of salts of hyaluronic acid with a basic anesthetic containing aliphatics and/or amino groups, particularly salts with benzydamine or bupivacaine.
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: May 1, 2001
    Assignee: Fidia, S.p.A.
    Inventors: Aurelio Romeo, Bruno Silvestrini, Gunter Kirschner
  • Patent number: 6066340
    Abstract: The present invention is directed to a microsphere for the controlled release of a biologically active molecule which comprises a biologically active molecule and an ester of hyaluronic acid or mixtures of said esters of hyaluronic acids, and wherein said biologically active molecule is surrounded by or adhered to said ester of hyaluronic acid, and wherein said microsphere has a diameter of between 1 .mu.m to 100 .mu.m.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: May 23, 2000
    Assignee: Fidia S.p.A.
    Inventors: Lanfranco Callegaro, Aurelio Romeo, Luca Benedetti
  • Patent number: 6039970
    Abstract: The present invention is directed to a microsphere for the controlled release of a biologically active molecule which comprises a biologically active molecule and an ester of hyaluronic acid or mixtures of said esters of hyaluronic acids, and wherein said biologically active molecule is surrounded by or adhered to said ester of hyaluronic acid, and wherein said microsphere has a diameter of between 1 .mu.m to 100 .mu.m.
    Type: Grant
    Filed: January 13, 1999
    Date of Patent: March 21, 2000
    Assignee: Fidia S.p.A.
    Inventors: Lanfranco Callegaro, Aurelio Romeo, Luca Benedetti
  • Patent number: 5925626
    Abstract: Two pharmaceutically useful fractions of hyaluronic acid are obtained comprising a first fraction with a molecular weight between 50,000 and 100,000 which is useful for wound healing, and a second fraction having a molecular weight between 500,000 and 730,000 which is useful for intraocular and intraarticular injections.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 20, 1999
    Assignee: Fidia S.p.A.
    Inventors: Francesco della Valle, Aurelio Romeo
  • Patent number: 5879359
    Abstract: The present invention is drawn to medical devices comprising biodegradable guide channels for use in the repair and regeneration of nerve tissue. The guide channels of the present invention comprise interlaced threads imbedded in a matrix, wherein both the matrix and the threads comprise biocompatible and bioabsorbable esters of hyaluronic acid. The matrix of the present invention further optionally comprises biologically or pharmacologically active factors in association with the guide channels.
    Type: Grant
    Filed: May 13, 1997
    Date of Patent: March 9, 1999
    Assignee: Fidia S.p.A.
    Inventors: Franco Dorigatti, Giorgio Favaro, Lanfranco Callegaro, Aurelio Romeo
  • Patent number: 5849717
    Abstract: Disclosed are derivatives of gangliosides and of N-acyl-N-lyso-gangliosides, of N'-acyl-N'-lyso-gangliosides and N,N'-di- or poly-acyl-N,N'-di-lyso-gangliosides, in which at least one of the hydroxyl groups in the saccharide, sialic or ceramide residues is esterified with sulfuric acid, functional derivatives thereof, and their salts with either inorganic or organic bases and the acid addition salts, except persulfated derivatives at the hydroxyl, sialic and ceramide groups of the GM.sub.1, GD.sub.1a, GD.sub.1b and GT.sub.1b gangliosides. Such compounds have antineurotoxic and neurotogenic activity and may therefore be used in pharmaceutical preparations. Also a marked modulating effect on the expression of the CD.sub.4 molecule in immune system cells has been shown.
    Type: Grant
    Filed: January 31, 1996
    Date of Patent: December 15, 1998
    Assignee: Fidia S.p.A.
    Inventors: Aurelio Romeo, Gunter Kirschner, Carlo Chizzolini, Hari Manev, Laura Facci
  • Patent number: 5824335
    Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable non-woven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric materials constitute threads embedded in a matrix, wherein both the matrix and the threads constitute auto-crosslinked hyaluronic acid.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 20, 1998
    Inventors: Franco Dorigatti, Lanfranco Callegaro, Aurelio Romeo
  • Patent number: 5795869
    Abstract: Semisynthetic analogues of gangliosides selected from the group consisting of N-sulfo-, N-hydrocarbyl-sulfonyl- and N-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N'-acyl derivatives thereof, N'-sulfo-, N'-hydrocarbylsulfonyl- and N'-hydrocarbyloxy-sulfonyl-N,N'-dilyso-gangliosides and the N-acyl derivatives thereof, N,N'-di or polysulfo-N,N'-di- or poly-lyso-gangliosides, N,N'-di- or polyhydrocarbylsulfonyl-N,N'-di- or poly-lyso-gangliosides and N,N'-di- or polyhydrocarbyloxy-N,N'-di- or poly-lyso-gangliosides, and functional derivatives thereof, and salts of these compounds, have protective activity against neurotoxicity induced by excitatory amino acids and are foreseen to be used in therapy in the nervous system and in modulating of the expression of determinants such as CD.sub.4 on the surface of human cells in the immune system.
    Type: Grant
    Filed: November 2, 1995
    Date of Patent: August 18, 1998
    Assignee: Fidia S.p.A.
    Inventors: Aurelio Romeo, Gunter Kirschner, Carlo Chizzolini, Hari Manev, Laura Facci
  • Patent number: 5792858
    Abstract: Novel derivatives of lysophingolipids free from sialic acids which are N-acyllysosphingolipids having one of the two formulae: ##STR1## in which -A- stands for the group --CH.dbd.CH-- or --CH.sub.2 --CH.sub.2 --, n.sub.1 is a whole number of between 6 and 18, n.sub.2 is a whole number of between 11 and 15, X is a hydrogen atom or the residue of a monosaccharide or a disaccharide or phosphorylcholine and R represents an alkyl radical derived from a saturated or unsaturated aliphatic carboxylic acid having from 2 to 24 carbon atoms substituted by one or more polar groups. The lysosphingolipid derivatives of the invention exhibit an inhibiting action on protein-kinase C activation and, thus, can be utilized in therapies for various pathologies of the nervous system.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: August 11, 1998
    Assignee: FIDIA S.p.A.
    Inventors: Francesco Della Valle, Aurelio Romeo