Patents by Inventor Axel Wein

Axel Wein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090150315
    Abstract: In one embodiment, the invention provides methods for predicting a clinical outcome of a patient's neoplastic disease comprising: (a) determining a predictor value algorithmically using patient sample values for (1) at least one tumor marker or at least one immune marker, and (2) at least one marker that is (i) an extracellular matrix (ECM) marker (ii) a marker that is indicative of extracellular matrix synthesis (fibrogenesis), or (iii) a marker that is indicative of extracellular matrix degradation (fibrolysis); and (b) predicting the clinical outcome of the neoplastic disease by evaluating the predictor value.
    Type: Application
    Filed: July 28, 2006
    Publication date: June 11, 2009
    Applicant: Siemens Healthcare Diagnostics Inc.
    Inventors: Ralph Wirtz, Manuela Averdick, Wolfgang Bruckl, Axel Wein, Robert P. Thiel
  • Publication number: 20080311567
    Abstract: The invention relates to a method (i) for detecting a carcinoma, especially an adenocarcinoma, preferably a gastrointestinal carcinoma and more preferably a colorectal carcinoma, (ii) for predicting metastases, preferably liver metastases, depending on a primary colon carcinoma and/or (iii) for predicting the response of metastases to a 5-fluorouracil-containing chemotherapy. The inventive method comprises determining a gene expression profile of 120 marker genes or a selection thereof.
    Type: Application
    Filed: July 29, 2005
    Publication date: December 18, 2008
    Inventors: Wolfgang Michael Bruckl, Axel Wein, Marc Munnes, Ralph Markus Wirtz