Patents by Inventor Ayelet MAROM

Ayelet MAROM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10611839
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: April 7, 2020
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Ayelet Marom
  • Publication number: 20180327493
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 15, 2018
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Ayelet MAROM
  • Patent number: 10066014
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: September 4, 2018
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Idit Shachar, Inbal Binsky, Ayelet Marom
  • Publication number: 20170260270
    Abstract: An isolated antibody comprising an antigen recognition domain which specifically binds CD84 and (i) down regulates the anti-apoptotic activity of stromal cells on chronic lymphocytic leukemia (CLL) cells; and/or (ii) induces mobilization of CLL cells from the bone marrow. Also provided are antibodies comprising antigen recognition domains comprising complementarity determining regions as indicated and uses thereof.
    Type: Application
    Filed: February 5, 2015
    Publication date: September 14, 2017
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Idit SHACHAR, Inbal BINSKY, Ayelet MAROM